Citation Impact
Citing Papers
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
2009 Standout
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
2002
Transport of amphipathic anions by human multidrug resistance protein 3.
2000
Promoter Choice Determines Splice Site Selection in Protocadherin α and γ Pre-mRNA Splicing
2002 StandoutNobel
Expression and Localization of Multidrug Resistant Protein mrp2 in Rat Small Intestine
2000
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
2001 Standout
The MRP family of drug efflux pumps
2003
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
2000
Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice
2016
ATP binding cassette transporter gene expression in rat liver progenitor cells
2003
Analysis of the In Vivo Functions of Mrp3
2005
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
2004
cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)1
1998
Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).
2002
Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)
2001
An inventory of the human ABC proteins
1999
Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells
1999
Expression of members of the multidrug resistance protein family in human term placenta
2000
Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines
1999
Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization
2007 StandoutNobel
Molecular Pathogenesis of Cholestasis
1998
Energetics of overall metabolic reactions of thermophilic and hyperthermophilic Archaea and Bacteria
2001
P-glycoprotein: from genomics to mechanism
2003
Archaic chaos: intrinsically disordered proteins in Archaea
2010
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis
1999
Thermophilic Adaptation of Proteins
2001
The first evidence of anaerobic CO oxidation coupled with H2 production by a hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent
2004
Principles of nanoparticle design for overcoming biological barriers to drug delivery
2015 Standout
Molecular characterisation of soft tissue tumours: a gene expression study
2002 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
Integration sites for genetic elements in prokaryotic tRNA and tmRNA genes: sublocation preference of integrase subfamilies
2002
BILE ACID TRANSPORT
1999
Intracellular cholesterol transport
1999
The lipids of archaebacteria
1988
The ABC transporter PGP-2 from Caenorhabditis elegans is expressed in the sensory neuron pair AWA and contributes to lysosome formation and lipid storage within the intestine
2005
Biochemical and molecular aspects of genetic disorders of bilirubin metabolism
1998
Drug-Induced Hepatotoxicity
2003 Standout
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
2009 StandoutNobel
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Nanocarriers as an emerging platform for cancer therapy
2007 Standout
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
2005
PHAST: A Fast Phage Search Tool
2011 Standout
Transport of Bile Acids, Sulfated Steroids, Estradiol 17-β-d-Glucuronide, and Leukotriene C4 by Human Multidrug Resistance Protein 8 (ABCC11)
2004
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
2002 Standout
IgG4-Related Disease
2012 Standout
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Transport of Cyclic Nucleotides and Estradiol 17-β-d-Glucuronide by Multidrug Resistance Protein 4
2001
Extremophiles and their adaptation to hot environments
1999
Targeting multidrug resistance in cancer
2006 Standout
Molecular cloning and characterization of the murine bile salt export pump
2000
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Serologic issues in IgG4-related systemic disease and autoimmune pancreatitis
2010
Biliary lipids and cholesterol gallstone disease
2008
Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery
2012 Standout
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
2001
Sulfur-inhibited Thermosphaera aggregans sp. nov., a new genus of hyperthermophilic archaea isolated after its prediction from environmentally derived 16S rRNA sequences
1998
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
1998
Membrane lipids: where they are and how they behave
2008 Standout
Familial intrahepatic cholestasis 1: Studies of localization and function
2001
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Hyperthermophilic Enzymes: Sources, Uses, and Molecular Mechanisms for Thermostability
2001 Standout
Characterization of the Human Multidrug Resistance Protein Isoform Mrp3 Localized to the Basolateral Hepatocyte Membrane
1999
Recent Advances in Autoimmune Pancreatitis
2015
ABC lipid transporters: Extruders, flippases, or flopless activators?
2005
Microtubules as a target for anticancer drugs
2004 Standout
IgG4-related disease
2014 Standout
Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport
2006
P4 ATPases - Lipid flippases and their role in disease
2009
Archaea predominate among ammonia-oxidizing prokaryotes in soils
2006 StandoutNature
The Complexities of Hepatic Drug Transport: Current Knowledge and Emerging Concepts
2004
Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor
2001
MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
1999
A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion
2004
Hepatobiliary transport
2000
Severe Cholestasis Induced by Cholic Acid Feeding in Knockout Mice of Sister of P–Glycoprotein
2003
Anaerobic respiration with elemental sulfur and with disulfides
1998
Utilization of a right-handed coiled-coil protein from archaebacterium Staphylothermus marinus as a carrier for cisplatin.
2009
Organization of the bacterial chromosome
1990
Hyperthermophilic procaryotes
1996
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
Gut Microbiota in Health and Disease
2010 Standout
Biology, ecology, and biotechnological applications of anaerobic bacteria adapted to environmental stresses in temperature, pH, salinity, or substrates
1993
Tumour stem cells and drug resistance
2005 Standout
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Cloning and Expression of Murine Sister of P-Glycoprotein Reveals a More Discriminating Transporter ThanMDR1/P-Glycoprotein
2000
Novel folded protein domains generated by combinatorial shuffling of polypeptide segments
2000 StandoutNobel
Pyrococcus furiosus sp. nov. represents a novel genus of marine heterotrophic archaebacteria growing optimally at 100�C
1986
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Hyperthermus butylicus, a hyperthermophilic sulfur-reducing archaebacterium that ferments peptides
1990
Targeted inactivation of sister of P-glycoprotein gene ( spgp ) in mice results in nonprogressive but persistent intrahepatic cholestasis
2001
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Pyrobaculum gen. nov., a new genus of neutrophilic, rod-shaped archaebacteria from continental solfataras growing optimally at 100�C
1987
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Bile Salt Transporters: Molecular Characterization, Function, and Regulation
2003
Keratin Degradation by Fervidobacterium pennavorans, a Novel Thermophilic Anaerobic Species of the Order Thermotogales
1996
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Mammalian ABC Transporters in Health and Disease
2002
Extremely Thermophilic Fermentative Archaebacteria of the Genus Desulfurococcus from Deep-Sea Hydrothermal Vents
1988
Palaeococcus ferrophilus gen. nov., sp. nov., a barophilic, hyperthermophilic archaeon from a deep-sea hydrothermal vent chimney.
2000
Microbial Fuel Cells: Methodology and Technology
2006 Standout
Archaea in coastal marine environments.
1992 Standout
Thermococcus stetteri sp. nov., a New Extremely Thermophilic Marine Sulfur-Metabolizing Archaebacterium
1989
Methanogens and the diversity of archaebacteria
1987
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome.
1989
Pyrococcus abyssi sp. nov., a new hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent
1993
The Mononuclear Molybdenum Enzymes
2014 Standout
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Thermococcus profundus sp. nov., A New Hyperthermophilic Archaeon Isolated from a Deep-sea Hydrothermal Vent
1994
Drug–Induced Liver Injury: Mechanisms and Test Systems
2001
Intrahepatic cholestasis of pregnancy
2009
Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis
2001
Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya.
1990 Standout
Molecular Pathogenesis of Cholestasis
2004
Effects of Hydrostatic Pressure on Growth of Hyperthermophilic Archaebacteria from the Juan de Fuca Ridge
1991
Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.
2000
Works of Jerzy Madon being referenced
Transport Function and Hepatocellular Localization of mrp6 in Rat Liver
2000
Functional expression of the rat liver canalicular isoform of the multidrug resistance‐associated protein
1997
Site-specific integration and excision of pMEA100 in Nocardia mediterranei
1987
The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver
1998
Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
2000
DNA-dependent RNA polymerase from the extremely halophilic archaebacterium Halococcus morrhuae
1983
A plasmid from the methylotrophic actinomycete Amycolatopsis methanolica capable of site-specific integration
1994
Transport Function and Hepatocellular Localization of mrp6 in Rat Liver
2000
Staphylothermus marinus sp. nov. Represents a Novel Genus of Extremely Thermophilic Submarine Heterotrophic Archaebacteria Growing up to 98 °C
1986
A Form of the DNA‐Dependent RNA Polymerase of Halobacterium halobium, Containing an Additional Component, Is Able to Transcribe Native DNA
1983
DNA-Dependent RNA Polymerases of the three Orders of Methanogens
1986