Citation Impact
Citing Papers
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
2007 Standout
Sirtuins as regulators of metabolism and healthspan
2012 Standout
Analysis of Hypoxia-Induced Metabolic Reprogramming
2014 StandoutNobel
Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance
2008
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
2007
Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels
2010
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
2006 Standout
Oncogenic kinase signalling
2001 StandoutNature
The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function
2005
Computational Enzyme Design
2013 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Regulation of the pyruvate dehydrogenase complex
2006
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-α transgenic mice
2003
Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony
2006
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Hormonal Regulation of Hepatic Glucose Production in Health and Disease
2011
Phytochromes and light signal perception by plants—an emerging synthesis
2000 StandoutNature
Photomorphogenesis: Light receptor kinases in plants!
1999
Energy Metabolism in the Normal and Failing Heart: Potential for Therapeutic Interventions
2002
Mitochondria: More Than Just a Powerhouse
2006 Standout
Control of pyruvate dehydrogenase kinase gene expression
2001
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Reactivation of Peroxisome Proliferator-activated Receptor α Is Associated with Contractile Dysfunction in Hypertrophied Rat Heart
2001
Constructing Azide-Labeled Cell Surfaces Using Polysaccharide Biosynthetic Pathways
2003 StandoutNobel
Hypoxia in Vivo Decreases Peroxisome Proliferator-Activated Receptor α-Regulated Gene Expression in Rat Heart
2001
Partial fatty acid oxidation inhibitors for stable angina
2002
Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway
2002 StandoutNobel
Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
2015
Regulation of cancer cell metabolism
2011 Standout
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
2021
Diverging regulation of pyruvate dehydrogenase kinase isoform gene expression in cultured human muscle cells
2005
Role of Peroxisome Proliferator-Activated Receptor-α in the Mechanism Underlying Changes in Renal Pyruvate Dehydrogenase Kinase Isoform 4 Protein Expression in Starvation and after Refeeding
2001
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Alterations in energy metabolism in cardiomyopathies
2007
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
2002
Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms
2001
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Branched-chain amino acids in metabolic signalling and insulin resistance
2014
Ethylene Biosynthesis and Signaling Networks
2002 Standout
Signaling—2000 and Beyond
2000 Standout
Mechanisms and structures of crotonase superfamily enzymes – How nature controls enolate and oxyanion reactivity
2008
Identification of ERRα as a specific partner of PGC‐1α for the activation of PDK4 gene expression in muscle
2006
Metabolic control through the PGC-1 family of transcription coactivators
2005 Standout
Regulation of hepatic fat and glucose oxidation in rats with lipid-induced hepatic insulin resistance
2011
Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment
2019
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Involvement of a Mitochondrial Phosphatase in the Regulation of ATP Production and Insulin Secretion in Pancreatic β Cells
2005
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization
2015
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons
2010
Glycolysis and pyruvate oxidation in cardiac hypertrophy—Why so unbalanced?
2003
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
2013
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Energy Metabolism in the Hypertrophied Heart
2002
Adaptive Increase in Pyruvate Dehydrogenase Kinase 4 during Starvation Is Mediated by Peroxisome Proliferator-Activated Receptor α
2001
Energy Metabolism in the Liver
2014 Standout
Genetic engineering of recombinant glycoproteins and glycosylation pathway in mammalian host cells
1999
Role of changes in cardiac metabolism in development of diabetic cardiomyopathy
2006
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
2011 Standout
The intrinsic circadian clock within the cardiomyocyte
2005
Obstructive sleep apnoea and its cardiovascular consequences
2008 Standout
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts
2002
Cryptochrome: The Second Photoactive Pigment in the Eye and Its Role in Circadian Photoreception
2000 StandoutNobel
Selective Modification of Pyruvate Dehydrogenase Kinase Isoform Expression in Rat Pancreatic Islets Elicited by Starvation and Activation of Peroxisome Proliferator–Activated Receptor-α
2001
Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs
2003
Effect of Short-Term Fasting and Refeeding on Transcriptional Regulation of Metabolic Genes in Human Skeletal Muscle
2003
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Peroxisome-proliferator-activated receptor-α (PPARα) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
2002
The protein kinases of Caenorhabditis elegans : A model for signal transduction in multicellular organisms
1999
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression
2000
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone
2003
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Mammalian Hibernation: Cellular and Molecular Responses to Depressed Metabolism and Low Temperature
2003
Evaluation of the role of peroxisome-proliferator-activated receptor α in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism
2002
The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes
2004
Mitochondrial-Nuclear Communications
2007
Peroxisome Proliferator-Activated Receptor-α Regulates Fatty Acid Utilization in Primary Human Skeletal Muscle Cells
2002
Diabetic Cardiomyopathy
2018 Standout
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
PKS1, a Substrate Phosphorylated by Phytochrome That Modulates Light Signaling in Arabidopsis
1999 Science
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Uncoupling protein 3 transcription is regulated by peroxisome proliferator‐activated receptor α in the adult rodent heart
2001
Two-Component Signal Transduction
2000 Standout
Insulin Regulation of Skeletal Muscle PDK4 mRNA Expression Is Impaired in Acute Insulin-Resistant States
2006
New Directions in Glycoprotein Engineering
2000 StandoutNobel
Muscle fiber type comparison of PDH kinase activity and isoform expression in fed and fasted rats
2001
Chemoselective Approaches to Glycoprotein Assembly
2001 StandoutNobel
Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
2003
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation
2013 Standout
Divergent Evolution of Enzymatic Function: Mechanistically Diverse Superfamilies and Functionally Distinct Suprafamilies
2001
Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance
2014
Metal–Organic Frameworks in Biomedicine
2011 Standout
The Microbial Engines That Drive Earth's Biogeochemical Cycles
2008 StandoutScience
Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism
2004
Light: an indicator of time and place
2000
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Regulation of Pyruvate Dehydrogenase Kinase Expression by Peroxisome Proliferator–Activated Receptor-α Ligands, Glucocorticoids, and Insulin
2002
Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex
1998
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Regulation of the pyruvate dehydrogenase complex
2006
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
2002
Patterns of gene expression in atrophying skeletal muscles: response to food deprivation
2002
Works of Jerzy Jaśkiewicz being referenced
Expression of metalloproteinases (MMP-2 and MMP-9) in basal-cell carcinoma
2016
Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms
2002
Primary Structure and Tissue-specific Expression of Human β-Hydroxyisobutyryl-coenzyme A Hydrolase
1996
Ethanol and oleate inhibition of α-ketoisovalerate and 3-hydroxyisobutyrate metabolism by isolated hepatocytes
1992
Effect of Dietary Protein on the Liver Content and Subunit Composition of the Branched-Chain α-Ketoacid Dehydrogenase Complex
1994
Dietary Control and Tissue Specific Expression of Branched-Chain α-Ketoacid Dehydrogenase Kinase
1995
Coordinated Expression of Valine Catabolic Enzymes During Adipogenesis: Analysis of Activity, mRNA, Protein Levels, and Metabolic Consequences
1994
Starvation Increases the Amount of Pyruvate Dehydrogenase Kinase in Several Mammalian Tissues
2000
Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart
1998
Studies on the regulation of the mitochondrial α-ketoacid dehydrogenase complexes and their kinases
1997
Site-directed mutagenesis of phosphorylation sites of the branched chain alpha-ketoacid dehydrogenase complex
1994
Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation
2006