Jens Lachmann

Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory

The Phosphoinositide Kinase PIKfyve Promotes Cathepsin-S-Mediated Major Histocompatibility Complex Class II Antigen Presentation

The Mon1-Ccz1 Complex Is the GEF of the Late Endosomal Rab7 Homolog Ypt7

The NLRP3 inflammasome: molecular activation and regulation to therapeutics

CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity

The molecular machinery of regulated cell death

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3

Fluorescence nanoscopy in cell biology

Differential Regulation of Lipoprotein and Hepatitis C Virus Secretion by Rab1b

Endosome maturation

Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site

Role of Rab GTPases in Membrane Traffic and Cell Physiology

Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity

Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion

Multivalent Rab interactions determine tether-mediated membrane fusion

CORVET and HOPS tethering complexes–coordinators of endosome and lysosome fusion

New insights into autophagosome–lysosome fusion

Autophagy pathway: Cellular and molecular mechanisms

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

Tethering complexes in the endocytic pathway: CORVET and HOPS

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

Defined Subunit Arrangement and Rab Interactions Are Required for Functionality of the HOPS Tethering Complex

Tracking of the dynamic localization of the Rab-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles

Functional Separation of Endosomal Fusion Factors and the Class C Core Vacuole/Endosome Tethering (CORVET) Complex in Endosome Biogenesis

Rab GTPases and tethering in the yeast endocytic pathway

The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles

The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3