Citation Impact
Citing Papers
Selective Activation of Adenosine A 2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis
2012
2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease
2010 Standout
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
2007 Standout
Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis
2007
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
2009
Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production
2011
Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis
2009
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
Differentiation Stage-Specific Requirement in Hypoxia-Inducible Factor-1α–Regulated Glycolytic Pathway during Murine B Cell Development in Bone Marrow
2009 StandoutNobel
1,3,7-Trimethylxanthine (Caffeine) May Exacerbate Acute Inflammatory Liver Injury by Weakening the Physiological Immunosuppressive Mechanism
2007
NKT Cell Activation Mediates Neutrophil IFN-γ Production and Renal Ischemia-Reperfusion Injury
2007
SP1-Dependent Induction of CD39 Facilitates Hepatic Ischemic Preconditioning
2010
Systematic Comparison of Gene Expression between Murine Memory and Naive B Cells Demonstrates That Memory B Cells Have Unique Signaling Capabilities
2008
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions
2014
Characterization of human and rodent native and recombinant adenosine A2B receptors by radioligand binding studies
2006
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Cl-IB-MECA [2-Chloro-N6-(3-iodobenzyl)adenosine-5′-N-methylcarboxamide] Reduces Ischemia/Reperfusion Injury in Mice by Activating the A Adenosine Receptor
2006
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation
2012
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Adenosine, adenosine A2A antagonists, and Parkinson's disease
2009
Adenosine A2A receptors and brain injury: Broad spectrum of neuroprotection, multifaceted actions and “fine tuning” modulation
2007
Delayed graft function in kidney transplantation
2004 Standout
2-Dialkynyl derivatives of (N)-methanocarba nucleosides: ‘Clickable’ A3 adenosine receptor-selective agonists
2009
A3adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis
2006
The ‘danger’ sensors that STOP the immune response: the A2 adenosine receptors?
2005
Regadenoson: A New Myocardial Stress Agent
2009
Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
2007
Nucleotide signalling during inflammation
2014 StandoutNature
Adenosine A2A receptor activation reduces inflammation and preserves pulmonary function in an in vivo model of lung transplantation
2005
Extracellular adenosine triphosphate and adenosine in cancer
2010
Adenosine in the spinal cord and periphery: release and regulation of pain
2003
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow–derived cells
2003
A2B Adenosine Receptor Gene Deletion Attenuates Murine Colitis
2008
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
2011
Analysis of A2a receptor-deficient mice reveals no significant compensatory increases in the expression of A2b, A1, and A3 adenosine receptors in lymphoid organs
2003
Hypoxia and Inflammation
2011 Standout
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Cellular pathophysiology of ischemic acute kidney injury
2011 Standout
Animal models for the study of adenosine receptor function
2004
Adenosine receptors as therapeutic targets
2006 Standout
Purinergic receptors in gastrointestinal inflammation
2007
Targeting iNKT cells for the treatment of sickle cell disease
2011
Purinergic regulation of the immune system
2016
Pathological pain and the neuroimmune interface
2014
CD73: a potent suppressor of antitumor immune responses
2012
Aspects of the general biology of adenosine A2A signaling
2007
Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury
2009
A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG-64Cu
2009
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
2011 Standout
Kidney ischemic preconditioning
2002
Synergistic Up-Regulation of Vascular Endothelial Growth Factor Expression in Murine Macrophages by Adenosine A2A Receptor Agonists and Endotoxin
2002
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion
2007
Adenosine Inhibits Tumor Necrosis Factor-α Release from Mouse Peritoneal Macrophages via A2A and A2B but Not the A3 Adenosine Receptor
2006
Functional effects of enhancing or silencing adenosine A2breceptors in cardiac fibroblasts
2004
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
2013
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney
2006
Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model
2008
Adenosine A2Areceptor activation reduces infarct size in the isolated, perfused mouse heart by inhibiting resident cardiac mast cell degranulation
2008
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
Adenosine A2AReceptors in Bone Marrow-Derived Cells But Not in Forebrain Neurons Are Important Contributors to 3-Nitropropionic Acid-Induced Striatal Damage as Revealed by Cell-Type-Selective Inactivation
2006
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
The immunology of stroke: from mechanisms to translation
2011 Standout
Activation of A2A Adenosine Receptor Attenuates Intestinal Inflammation in Animal Models of Inflammatory Bowel Disease
2005
Regulation of immune cells by local-tissue oxygen tension: HIF1α and adenosine receptors
2005
Adenosine receptor agonists: from basic medicinal chemistry to clinical development
2003
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
The role of the immune system in the generation of neuropathic pain
2012
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
The birth and postnatal development of purinergic signalling
2010
Adenosine, an endogenous distress signal, modulates tissue damage and repair
2007
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Use of a hanging-weight system for liver ischemic preconditioning in mice
2008
New potent and selective A1 adenosine receptor agonists
2004
Autocrine Adenosine Signaling Promotes Regulatory T Cell–Mediated Renal Protection
2012
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Monitoring changes in gene expression in renal ischemia-reperfusion in the rat
2002
Adenosine receptors as drug targets — what are the challenges?
2013
Blocking Striatal Adenosine A2A Receptors: A New Strategy for Basal Ganglia Disorders
2007
Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor
2015
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Adenosine
2014
Monocytes/Macrophages Control Resolution of Transient Inflammatory Pain
2014
Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)
2016
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Characterization of the A2B Adenosine Receptor from Mouse, Rabbit, and Dog
2009
A2AAdenosine Receptor Activation Improves Survival in Mouse Models of Endotoxemia and Sepsis
2004
G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions
2012
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
2006
The A3 Adenosine Receptor Agonist CP-532,903 [N6-(2,5-Dichlorobenzyl)-3′-aminoadenosine-5′-N-methylcarboxamide] Protects against Myocardial Ischemia/Reperfusion Injury via the Sarcolemmal ATP-Sensitive Potassium Channel
2007
Microglia: biology and pathology
2009
Exploring the full spectrum of macrophage activation
2008 Standout
Functional and cytoarchitectural spinal cord protection by ATL-146e after ischemia/reperfusion is mediated by adenosine receptor agonism
2006
Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure
2001
Shaping of monocyte and macrophage function by adenosine receptors
2006
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
2016
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages
2004
Recent advances in Sonogashira reactions
2011 Standout
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Therapeutic Anti-Inflammatory Effects of Myeloid Cell Adenosine Receptor A2a Stimulation in Lipopolysaccharide-Induced Lung Injury
2007
N6-Methoxy-2-alkynyladenosine Derivatives as Highly Potent and Selective Ligands at the Human A3Adenosine Receptor
2007
Strategies for Spinal Cord Protection during Descending Thoracic and Thoracoabdominal Aortic Surgery: Up-to-date Experimental and Clinical Results - A review
2002
Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility
2008
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Practical synthesis of biaryl colchicinoids containing 3′,4′-catechol ether-based A-rings via Suzuki cross-coupling with ligandless palladium in water
2003
Regulatory T Cells and Human Disease
2020 StandoutNobel
Cutting Edge: Critical Role for A2A Adenosine Receptors in the T Cell-Mediated Regulation of Colitis
2006
Physiological Control of Immune Response and Inflammatory Tissue Damage by Hypoxia -Inducible Factors and Adenosine A2AReceptors
2004 Nobel
The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs
2006
Structure of the adenosine A2A receptor bound to an engineered G protein
2016 Nature
Prediction of cytochrome P450 isoform responsible for metabolizing a drug molecule
2010
Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
2011 StandoutNobel
Catalytic Enantioselective Conversion of Epoxides to Thiiranes
2016 StandoutNobel
Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation
2006
Cutting Edge: Hypoxia-Inducible Factor 1α and Its Activation-Inducible Short Isoform I.1 Negatively Regulate Functions of CD4+ and CD8+ T Lymphocytes
2006
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Adenosine A2A Receptor Inactivation Increases Survival in Polymicrobial Sepsis
2006
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
2007
The subendothelial extracellular matrix modulates NF-κB activation by flow
2005
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Cardiac effects of adenosine in A2Areceptor knockout hearts: uncovering A2Breceptors
2002
Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors
2011
Endothelial Cell PECAM-1 Promotes Atherosclerotic Lesions in Areas of Disturbed Flow in ApoE-Deficient Mice
2008
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Decreased Capacity of Immune Cells to Cause Tissue Injury Mediates Kidney Ischemic Preconditioning
2006
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease
2010
A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice
2011
Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure
2001
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Blockade of A 2A receptors potently suppresses the metastasis of CD73 + tumors
2013
Boronic acids in medicinal chemistry: anticancer, antibacterial and antiviral applications
2010
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
A2A adenosine receptors and C/EBPβ are crucially required for IL-10 production by macrophages exposed to Escherichia coli
2007
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-κB in A2A adenosine receptor induction
2005
Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
2011
Both MC5r and A2Ar Are Required for Protective Regulatory Immunity in the Spleen of Post–Experimental Autoimmune Uveitis in Mice
2013
Molecular Approach to Adenosine Receptors: Receptor-Mediated Mechanisms of Tissue Protection
2001
Renal Ischemia-Reperfusion Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4+ T Cells and IFN-γ
2006
Myocardial Infarct–Sparing Effect of Adenosine A2AReceptor Activation Is due to Its Action on CD4+T Lymphocytes
2006
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
2016
Activation of Adenosine 2A Receptors Attenuates Allograft Rejection and Alloantigen Recognition
2007
Infarct-Sparing Effect of A 2A -Adenosine Receptor Activation Is Due Primarily to Its Action on Lymphocytes
2005
Antimetastatic Effects of Blocking PD-1 and the Adenosine A2A Receptor
2014
Synthesis of combretastatins A-1 and B-1
2005
T Regulatory and Primed Uncommitted CD4 T Cells Express CD73, Which Suppresses Effector CD4 T Cells by Converting 5′-Adenosine Monophosphate to Adenosine
2006
Adenosine A 2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function
2008
The A2b adenosine receptor protects against vascular injury
2008
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Activation of A2A adenosine receptors inhibits expression of α4/β1 integrin (very late antigen-4) on stimulated human neutrophils
2003
Physiology of Microglia
2011 Standout
Works of Jayson Rieger being referenced
The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells
2009
Adenosine A2A Analogue Improves Neurologic Outcome after Spinal Cord Trauma in the Rabbit
2002
Systemic adenosine A2A agonist ameliorates ischemic reperfusion injury in the rabbit spinal cord
2001
Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling
2013
Cardioprotection by adenosine A2Aagonists in a canine model of myocardial stunning produced by multiple episodes of transient ischemia
2007
Adenosine A2A analogue ATL-146e reduces systemic tumor necrosing factor-α and spinal cord capillary platelet-endothelial cell adhesion molecule-1 expression after spinal cord ischemia
2002
An adenosine A2A agonist, ATL-146e, reduces paralysis and apoptosis during rabbit spinal cord reperfusion
2001
Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A2A-receptor–mediated coronary vasodilation
2002
Structure-Based Discovery of a Boronic Acid Bioisostere of Combretastatin A-4
2005
Enduring Reversal of Neuropathic Pain by a Single Intrathecal Injection of Adenosine 2A Receptor Agonists: A Novel Therapy for Neuropathic Pain
2009
Adenosine A2A agonist reduces paralysis after spinal cord ischemia: correlation with A2A receptor expression on motor neurons
2002
Comparative molecular field analysis of colchicine inhibition and tubulin polymerization for combretastatins binding to the colchicine binding site on β-tubulin
2000
Comparative molecular field analysis and QSAR on substrates binding to cytochrome P450 2D6
2003
Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion
2001
Cyclic AMP‐dependent inhibition of human neutrophil oxidative activity by substituted 2‐propynylcyclohexyl adenosine A2A receptor agonists
2001
Adenosine A2A receptor activation decreases reperfusion injury associated with high-flow reperfusion
2002
Human A2AAdenosine Receptors: High-Affinity Agonist Binding to Receptor-G Protein Complexes Containing Gβ4
2002
Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A2Areceptor agonist, in reperfused canine myocardium
2004
A2A adenosine receptor (AR) activation inhibits pro-inflammatory cytokine production by human CD4+ helper T cells and regulates Helicobacter-induced gastritis and bacterial persistence
2009
A2A Adenosine Receptor Induction Inhibits IFN-γ Production in Murine CD4+ T Cells
2005
Selective A2Aadenosine receptor activation reduces skin pressure ulcer formation and inflammation
2001
A2A Adenosine Receptors on Bone Marrow-Derived Cells Protect Liver from Ischemia-Reperfusion Injury
2005
Design, Synthesis, and Evaluation of Novel A2A Adenosine Receptor Agonists
2001
A2Aadenosine receptor-mediated inhibition of renal injury and neutrophil adhesion
2000
Effect of Novel A2AAdenosine Receptor Agonist ATL 313 onClostridium difficileToxin A-Induced Murine Ileal Enteritis
2006
Pharmacological Stress Myocardial Perfusion Imaging With the Potent and Selective A2AAdenosine Receptor Agonists ATL193 and ATL146e Administered by Either Intravenous Infusion or Bolus Injection
2001
Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow–derived cells or deletion of the A2A receptor on non-bone marrow–derived cells
2006
Adenosine A2AReceptor Stimulation Reduces Inflammation and Neointimal Growth in a Murine Carotid Ligation Model
2001