Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2012 StandoutScienceNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
2020 StandoutScience
Mechanism of auxin perception by the TIR1 ubiquitin ligase
2007 Nature
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin
2017
The Structure of the 26S Proteasome Subunit Rpn2 Reveals Its PC Repeat Domain as a Closed Toroid of Two Concentric α-Helical Rings
2012
Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran
2007
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
2011 Nature
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)
2011
The dynamic disulphide relay of quiescin sulphydryl oxidase
2012 StandoutNatureNobel
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition
2006
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
The JAZ family of repressors is the missing link in jasmonate signalling
2007 StandoutNature
JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
2007 StandoutNature
Principles for designing ideal protein structures
2012 StandoutNatureNobel
A Helical RGD Motif Promoting Cell Adhesion: Crystal Structures of the Helicobacter pylori Type IV Secretion System Pilus Protein CagL
2013
Towards automated crystallographic structure refinement with phenix.refine
2012 Standout
Crystal structure and association behaviour of the GluR2 amino‐terminal domain
2009
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Structure of the Human MutSα DNA Lesion Recognition Complex
2007 StandoutNobel
REFMAC5 for the refinement of macromolecular crystal structures
2011 Standout
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Structural and energetic basis of folded-protein transport by the FimD usher
2013 StandoutNatureNobel
Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme
2009 Nature
The coming of age of de novo protein design
2016 StandoutNatureNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection
2012
Molecular Basis for the Unique Role of the AAA+ Chaperone ClpV in Type VI Protein Secretion
2011
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope
2010 StandoutNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
De novo design of buttressed loops for sculpting protein functions
2024 StandoutNobel
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
The active conformation of human glucokinase is not altered by allosteric activators
2011
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs
2010 StandoutNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
2016
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing
2013
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes
2014 Science
Structural and Thermodynamic Analysis of a Conformationally Strained Circular Permutant of Barnase
2009
Self-Assembling 2D Arrays with de Novo Protein Building Blocks
2019 StandoutNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
2012
The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
2009 StandoutNature
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors
2011
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Atomic structure of the 75 MDa extremophile Sulfolobus turreted icosahedral virus determined by CryoEM and X-ray crystallography
2013
Works of Jay Painter being referenced
A molecular viewer for the analysis of TLS rigid-body motion in macromolecules
2005
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion
2006
TLSMDweb server for the generation of multi-group TLS models
2006