Standout Papers
Citation Impact
Citing Papers
H 2 S mediates O 2 sensing in the carotid body
2010
Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel
2004 Science
Abolition of Long-Term Stability of New Hippocampal Place Cell Maps by NMDA Receptor Blockade
1998 StandoutScienceNobel
Inherent variations in CO-H 2 S-mediated carotid body O 2 sensing mediate hypertension and pulmonary edema
2014
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
The selective neuronal NO synthase inhibitor 7-nitro-indazole blocks both long-term potentiation and depotentiation of field EPSPs in rat hippocampal CA1 in vivo
1996
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Calcineurin Inhibitors FK506 and SDZ ASM 981 Alleviate the Outcome of Focal Cerebral Ischemic/Reperfusion Injury
1999
NO Honey, I Don't Remember
1996
The heme synthesis and degradation pathways: role in oxidant sensitivity
2000
The heme oxygenase system and cellular defense mechanisms
2001
Cell Biology of Heme
1999
Identification of Hypoxia-response Element in the Human Endothelial Nitric-oxide Synthase Gene Promoter
2003
Low-dose carbon monoxide reduces airway hyperresponsiveness in mice
2003
Drosophila melanogaster NADPH–cytochrome P450 oxidoreductase: pronounced expression in antennae may be related toodorantclearance
1997
Spatio-temporal dynamics of cyclic AMP signals in an intact neural circuit
1996 StandoutNatureNobel
Synaptic plasticity: hippocampal LTP
1995
Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element
1997
A Molecular Switch for the Consolidation of Long‐Term Memory: cAMP‐Inducible Gene Expression
1995 StandoutNobel
Endogenous carbon monoxide in control of respiration
1998
Corticosterone promotes increased heme oxygenase-2 protein and transcript expression in the newborn rat brain
1996
Molecular Mechanisms of Nitric Oxide Actions in the Braina
1994
Carbon Monoxide Promotes Fas/CD95-induced Apoptosis in Jurkat Cells
2004
Role of carbon monoxide in l-glutamate-induced cardiovascular responses in nucleus tractus solitarius of conscious rats
1999
Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule
2004
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Haem oxygenase-1 prevents cell death by regulating cellular iron
1999
Nitric oxide synthases: Roles, tolls, and controls
1994 Standout
Only ‘de novo’ long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex
1995
Heme oxygenase–carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide?
1999
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
Signalling and Chromatin Fragmentation in Thymocyte Apoptosis
1994
Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice
1995 Nobel
Carbon monoxide and hypertension
2004
Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase
1996
The Immunosuppressant Drug FK506 Ameliorates Secondary Mitochondrial Dysfunction Following Transient Focal Cerebral Ischemia in the Rat
1997
Pitfalls using metalloporphyrins in carbon monoxide research
1997
Carbon monoxide‐induced vasorelaxation and the underlying mechanisms
1997
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Genetic analysis of nitric oxide synthase isoforms: targeted mutation in mice
1996
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity
1995
Cellular and subcellular localization of heme oxygenase-2 in monkey retina
2004
Amyloid Precursor Proteins Inhibit Heme Oxygenase Activity and Augment Neurotoxicity in Alzheimer's Disease
2000
Heme Oxygenase-2 Is a Hemoprotein and Binds Heme through Heme Regulatory Motifs That Are Not Involved in Heme Catalysis
1997
Calcium-induced activation of the mitochondrial permeability transition in hippocampal neurons
1998
Elevation of C-reactive protein in “active” coronary artery disease
1990
Role of carbon monoxide in heme-induced vasodilation
1997
Heme Oxygenase Activity: Current Methods and Applications
2003
Regional measurements of NO formedin vivoduring brain ischemia
1997
Bright and dark sides of nitric oxide in ischemic brain injury
1997
Nitric Oxide in the Nervous System
1995
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
Calcineurin and mitochondrial function in glutamate‐induced neuronal cell death
1996
Heme oxygenase-1 protects against vascular constriction and proliferation
2001
Nitric Oxide Acts Directly in the Presynaptic Neuron to Produce Long-Term Potentiationin Cultured Hippocampal Neurons
1996 StandoutNobel
Sensing hypoxia: physiology, genetics and epigenetics
2013
Atherosclerosis — An Inflammatory Disease
1999 Standout
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
1998
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
Cellular mechanisms of oxygen sensing at the carotid body: heme proteins and ion channels
2000
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal ltp in the range of the θ frequency
1995 StandoutNobel
CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation
1998 StandoutNobel
Carbon Monoxide Controls the Proliferation of Hypoxic Vascular Smooth Muscle Cells
1997
Vascular effects of a heme oxygenase inhibitor are enhanced in the absence of nitric oxide
2002
Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase
1996 StandoutNobel
Carbon monoxide in biology and medicine
2004
NO and CO as second messengers in oxygen sensing in the carotid body
1999
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
2002 Standout
Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body
2012
Heme oxygenase-1 and carbon monoxide in pulmonary medicine
2003
Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor.
1997
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Congenital Deafness and Sinoatrial Node Dysfunction in Mice Lacking Class D L-Type Ca2+ Channels
2000
Heme Oxygenase-2 Interaction with Metalloporphyrins: Function of Heme Regulatory Motifs
2001
Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory
1997 StandoutNobel
Hydrogen sulfide as a gasotransmitter
2010
Carbon Monoxide Neurotransmission Activated by CK2 Phosphorylation of Heme Oxygenase-2
2003
Prognostic Value of Myeloperoxidase in Patients with Chest Pain
2003
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells
2004
Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase
1998
Transgenic approaches to cognition
1995 StandoutNobel
Heme Oxygenase-1: Molecular Mechanisms of Gene Expression in Oxygen-Related Stress
2002
Cerebrovascular Effects of Carbon Monoxide
2002
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway
1999 StandoutNobel
High-Performance Caged Nitric Oxide: A New Molecular Design, Synthesis, and Photochemical Reaction
1997
Carbon Monoxide Dilates Cerebral Arterioles by Enhancing the Coupling of Ca 2+ Sparks to Ca 2+ -Activated K + Channels
2002
Role of Nitric Oxide in the Control of Cardiac Oxygen Consumption in B2-Kinin Receptor Knockout Mice
1999
Differential signaling pathways ofHO-1gene expression in pulmonary and systemic vascular cells
1999
A selective role of calcineurin Aα in synaptic depotentiation in hippocampus
1999 StandoutNobel
Neuronal Nitric Oxide Synthase Activation and Peroxynitrite Formation in Ischemic Stroke Linked to Neural Damage
1999
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP
2002 StandoutNobel
Caveolae compartmentalization of heme oxygenase‐1 in endothelial cells
2004
Heme oxygenase 1 is required for mammalian iron reutilization
1997 Nobel
Mitochondrial Dysfunction Is a Primary Event in Glutamate Neurotoxicity
1996
The Regulation of Heme Turnover and Carbon Monoxide Biosynthesis in Cultured Primary Rat Olfactory Receptor Neurons
1996
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.
1996
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction
2000
Postsynaptic Membrane Fusion and Long-Term Potentiation
1998 StandoutScienceNobel
Molecular mechanisms and therapeutic strategies related to nitric oxide
1995
Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis
1999
Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells
2002 StandoutNobel
Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide
1997 Nobel
Carbon Monoxide Inhibits T Lymphocyte Proliferation via Caspase-Dependent Pathway
2004
All-or-none potentiation at CA3-CA1 synapses
1998 StandoutNobel
Postischemic administration of FK506 reduces infarct volume following transient focal brain ischemia
1996
Carbon monoxide and cerebral microvascular tone in newborn pigs
1999
Pteridine biosynthesis and nitric oxide synthase in Physarum polycephalum
1994
Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets
2001
Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats
1996
XIV. International Union of Pharmacology Nomenclature in Nitric Oxide Research
1997 StandoutNobel
Putative mechanism of hypotensive action of platelet-activating factor in dogs.
1992 StandoutNobel
Signaling by Gasotransmitters
2009
MOLECULAR GENETIC ANALYSIS OF SYNAPTIC PLASTICITY, ACTIVITY-DEPENDENT NEURAL DEVELOPMENT, LEARNING, AND MEMORY IN THE MAMMALIAN BRAIN
1997 Nobel
Regulation of endothelial heme oxygenase activity during hypoxia is dependent on chelatable iron
2000
Interneurons of the hippocampus
1998 Standout
A Redox-triggered Ras-Effector Interaction
1998
Neuroprotective FK506 Does Not Alter In Vivo Nitric Oxide Production During Ischemia and Early Reperfusion in Rats
1999
Cellular and functional defects in a mouse model of heart failure
2000
THE HEME OXYGENASE SYSTEM:A Regulator of Second Messenger Gases
1997 Standout
Isoforms of nitric oxide synthase
1995
Regulation of biosynthesis of nitric oxide.
1994
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Absence of cerebellar long-term depression in mice lacking neuronal nitric oxide synthase.
1997 StandoutNobel
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Reduced stress defense in heme oxygenase 1-deficient cells
1997 Nobel
Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols.
1996
Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death.
1995 StandoutNobel
Direct demonstration of a physiological role for carbon monoxide in olfactory receptor neurons
1995
Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase
1997
Sinoatrial Node Dysfunction and Early Unexpected Death of Mice With a Defect of klotho Gene Expression
2004
Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
2001 StandoutNobel
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Cerebroprotective Effects of Aminoguanidine in a Rodent Model of Stroke
1996
Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide
1997
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
The role of hypoxia‐inducible factors in carotid body (patho) physiology
2018 StandoutNobel
Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury
1999
Nitric Oxide Synthase in Models of Focal Ischemia
1997
PIN: An Associated Protein Inhibitor of Neuronal Nitric Oxide Synthase
1996 Science
Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase
1994 Science
Nitric Oxide Induces Heme Oxygenase-1 Gene Expression and Carbon Monoxide Production in Vascular Smooth Muscle Cells
1997
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels
1999
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
NMDAR1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons.
1998
Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice
1996
The Selective Inhibitor of Neuronal Nitric Oxide Synthase, 7-Nitroindazole, Reduces the Delayed Neuronal Damage Due to Forebrain Ischemia in Rats
1998
Protein kinase G–regulated production of H 2 S governs oxygen sensing
2015 StandoutNobel
Toward a molecular definition of long-term memory storage
1996 StandoutNobel
A biochemist's view of long-term potentiation.
1996
Differential Effects of Heme Oxygenase Isoforms on Heme Mediation of Endothelial Intracellular Adhesion Molecule 1 Expression
1999
The Calmodulin Antagonist Trifluoperazine in Transient Focal Brain Ischemia in Rats
1997
THE REGULATION AND PHARMACOLOGY OF ENDOTHELIAL NITRIC OXIDE SYNTHASE
2005
Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
2002
Structural organization of the human neuronal nitric oxide synthase gene (NOS1)
1994
Retrograde Carbon Monoxide Is Required for Induction of Long-Term Potentiation in Rat Superior Cervical Ganglion
2001
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
1994
Transient up-regulation of P2Y2nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
1997 StandoutNobel
Cell Biology of Heme
1999
Reversing cerebellar long-term depression
2003 StandoutNobel
Oxygen sensing by the carotid body chemoreceptors
2000
Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs
2003
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
NMDAR1 Glutamate Receptor Subunit Isoforms in Neostriatal, Neocortical, and Hippocampal Nitric Oxide Synthase Neurons
1998
Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury
2000
Cerebellar Long-Term Depression: Characterization, Signal Transduction, and Functional Roles
2001
Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme.
1996
C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men
1999 Standout
H 2 S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea
2016 StandoutNobel
Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia
1998
Works of Jay Dinerman being referenced
Regulation of Endothelial Nitric-oxide Synthase during Hypoxia
1996
Increased neutrophil elastase release in unstable angina pectoris and acute myocardial infarction
1990
Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice.
1998
Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity
1994
Systemic and Coronary Hemodynamic Effects of Prostacyclin and Nitroprusside in Conscious Dogs
1988
Carbon monoxide: a role in carotid body chemoreception.
1995
Neutrophil function in ischemic heart disease.
1989
Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity.
1994
Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS
1994 StandoutScienceNobel
Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease.
1993
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity.
1993
Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation.
1996