Citation Impact
Citing Papers
The HER-2 Receptor and Breast Cancer: Ten Years of Targeted Anti–HER-2 Therapy and Personalized Medicine
2009
CDK 4/6 Inhibitor Palbociclib (PD0332991) in Rb+ Advanced Breast Cancer: Phase II Activity, Safety, and Predictive Biomarker Assessment
2014
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
2002 StandoutScienceNobel
Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer
2012 Standout
Impact of Common Epidermal Growth Factor Receptor and HER2 Variants on Receptor Activity and Inhibition by Lapatinib
2008
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study
2014 Standout
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Subcellular targeting by membrane lipids
2001
Abiotic Stress Signaling and Responses in Plants
2016 Standout
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
Genetic Analysis of α-Latrotoxin Receptors Reveals Functional Interdependence of CIRL/Latrophilin 1 and Neurexin 1α
2002 StandoutNobel
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein
2012
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Direct Interaction of Alzheimer's Disease-related Presenilin 1 with Armadillo Protein p0071
1999 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Pharmacological and nutritional agents promoting browning of white adipose tissue
2012
The complexity of Raf-1 regulation
1997
Distinct Mechanisms Mediate the Initial and Sustained Phases of Integrin-mediated Activation of the Raf/MEK/Mitogen-activated Protein Kinase Cascade
1998
Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats
2010
Correction: CDK4/ 6 inhibition provides a potent adjunct to Her2- targeted therapies in preclinical breast cancer models
2021
Targeting cell cycle and hormone receptor pathways in cancer
2013
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
Role of Iron (II)-2-Oxoglutarate-dependent Dioxygenases in the Generation of Hypoxia-induced Phosphatidic Acid through HIF-1/2 and von Hippel-Lindau-independent Mechanisms
2004
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
1995 StandoutNature
A CRISPR toolbox to study virus–host interactions
2017
Ceramide: an endogenous regulator of apoptosis and growth suppresion
1995
When Checkpoints Fail
1997 StandoutNobel
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Two Distinct Raf Domains Mediate Interaction with Ras
1995
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
1996 StandoutNature
Negative regulation of inflammation by SIRT1
2012
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes
2009
Enhanced Phagocytosis through Inhibition of de Novo Ceramide Synthesis
2003 StandoutNobel
Cyclin-dependent kinase inhibitor therapy for hematologic malignancies
2013
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The RIM/NIM Family of Neuronal C2 Domain Proteins
2000 StandoutNobel
Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis
1997 StandoutNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
1997
The Hallmarks of Aging
2013 Standout
Identification of the 14.3.3 ζ Domains Important for Self-association and Raf Binding
1995
Postmortem Delay Has Minimal Effect on Brain RNA Integrity
2007
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
1995
JAB1 Interacts with Both the Progesterone Receptor and SRC-1
2000
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
Cellular senescence: from physiology to pathology
2014 Standout
The role of glycosyl–phosphatidylinositol in signal transduction1Dedicated to Dr. Antonio Sanchez-Bueno.1
1998
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Molecular Pathways: CDK4 Inhibitors for Cancer Therapy
2014
A Water-Based Mechanism of Specificity and Resistance for Lapatinib with ErbB Family Kinases
2012
Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)
1999 Science
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Trastuzumab in the management of early and advanced stage breast cancer.
2007
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity.
1995
Transcriptional neoteny in the human brain
2009 StandoutNobel
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
1995
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction
1995 Science
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models
2014
Raf-1 N-Terminal Sequences Necessary for Ras-Raf Interaction and Signal Transduction
1995
Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells
1998
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Integrin Signaling
1999 StandoutScience
Functional association between Arf and RalA in active phospholipase D complex
1998
Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras.
1994
Uncoupling protein 1 expression and high-fat diets
2010
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor
2007 StandoutNobel
Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras.
1996 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Targeting CDK4 and CDK6: From Discovery to Therapy
2015
CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer
2014
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase
1994
Phospholipase Dα1 and Phosphatidic Acid Regulate NADPH Oxidase Activity and Production of Reactive Oxygen Species in ABA-Mediated Stomatal Closure inArabidopsis
2009
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Signal Transduction through MAP Kinase Cascades
1998 Standout
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition
2015
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.
1994
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Jay C. Strum being referenced
Regulation of Survivin by ErbB2 Signaling: Therapeutic Implications for ErbB2-Overexpressing Breast Cancers
2006
Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
2012
A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer
2006
Ceramide Triggers Meiotic Cell Cycle Progression in Xenopus Oocytes.
1995
Recovery and Expression of Messenger RNA from Postmortem Human Brain Tissue
2001
Raf-1 Kinase Possesses Distinct Binding Domains for Phosphatidylserine and Phosphatidic Acid
1996
GSK983: A novel compound with broad-spectrum antiviral activity
2009
Identification of Conditions That Facilitate the Expression of GST Fusions as Soluble, Full-Length Proteins
1995
Adipose Mitochondrial Biogenesis Is Suppressed in db/db and High-Fat Diet–Fed Mice and Improved by Rosiglitazone
2007
Evaluation of targeted bone marrow arrest by G1T28, a CDK4/6 inhibitor in clinical development to reduce chemotherapy-induced myelosuppression.
2015
Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling
1997
1-beta-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells.
1994
The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras
1994
Delineation of molecular mechanisms of sensitivity to lapatinib in breast cancer cell lines using global gene expression profiles
2007
CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury
2013
MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1
2009