Citation Impact
Citing Papers
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Cell entry mechanisms of SARS-CoV-2
2020 Standout
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana
2021 StandoutNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex
2020
Assessment of contact predictions in CASP12: Co‐evolution and deep learning coming of age
2017
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors
2016
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
New horizons in hypoxia signaling pathways
2017 StandoutNobel
Structure and Function of Photolyase and in Vivo Enzymology: 50th Anniversary
2008 StandoutNobel
Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
2017
Structural integration in hypoxia-inducible factors
2015 Nature
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Mechanisms of hypoxia signalling: new implications for nephrology
2019 StandoutNobel
In Vivo Generation of Flavoproteins with Modified Cofactors
2008
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Ultrafast spectroscopy of biological photoreceptors
2007
Targeting HIF2 in Clear Cell Renal Cell Carcinoma
2016 StandoutNobel
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
2016
Molecular basis of human CD22 function and therapeutic targeting
2017
Oxygen availability and metabolic adaptations
2016
High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers
2019
Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM
2021
Flavin‐based Blue‐light Photosensors: A Photobiophysics Update
2007
Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes
2022
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
2003 Standout
Fusion of DARPin to Aldolase Enables Visualization of Small Protein by Cryo-EM
2019
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein
2016
Animal Type 1 Cryptochromes
2007 StandoutNobel
Mechanism of Photosignaling by Drosophila Cryptochrome
2013 StandoutNobel
VHL, the story of a tumour suppressor gene
2014
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
2020 Standout
De novo design of buttressed loops for sculpting protein functions
2024 StandoutNobel
Highly Efficient Ultrafast Electron Injection from the Singlet MLCT Excited State of Copper(I) Diimine Complexes to TiO2 Nanoparticles
2012 StandoutNobel
Taking Snapshots of Photoexcited Molecules in Disordered Media by Using Pulsed Synchrotron X‐rays
2004
Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
2014 StandoutNobel
Design and Signaling Mechanism of Light-Regulated Histidine Kinases
2008
Structural characterization of mammalian bHLH-PAS transcription factors
2016
Photochemistry of flavoprotein light sensors
2014
Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome
2017 Nobel
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
2020 Standout
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
SARS-CoV-2 vaccines in development
2020 StandoutNature
Structural basis of receptor recognition by SARS-CoV-2
2020 StandoutNature
Redox Control of Protein Conformation in Flavoproteins
2009
The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice
2016
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
2017
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Structure and Function of Plant Photoreceptors
2010
Momentaufnahmen photoangeregter Moleküle in fehlgeordneten Medien mit gepulster Synchrotron‐Röntgenstrahlung
2004
Emerging Models for the Molecular Basis of Mammalian Circadian Timing
2014
Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein−Protein Interactions
2010
Microsecond Light-Induced Proton Transfer to Flavin in the Blue Light Sensor Plant Cryptochrome
2009
Reaction mechanism of Drosophila cryptochrome
2010 StandoutNobel
LOVely enzymes – towards engineering light‐controllable biocatalysts
2009
The von Hippel-Lindau Tumor Suppressor Gene
2020
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Electron Injection from Copper Diimine Sensitizers into TiO2: Structural Effects and Their Implications for Solar Energy Conversion Devices
2015 StandoutNobel
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
2016 Nature
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
2009
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
Ultrafast Dynamics of Flavins in Five Redox States
2008 StandoutNobel
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Signal transduction in light–oxygen–voltage receptors lacking the adduct-forming cysteine residue
2015
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Protein Structure Prediction Revolution and Its Implications for Medicine
2023 StandoutNobel
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
2015 Science
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS
2019
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
The Evolution of Flavin-Binding Photoreceptors: An Ancient Chromophore Serving Trendy Blue-Light Sensors
2012
PROBING TRANSIENT MOLECULAR STRUCTURES IN PHOTOCHEMICAL PROCESSES USING LASER-INITIATED TIME-RESOLVED X-RAY ABSORPTION SPECTROSCOPY
2005
Structure-based membrane dome mechanism for Piezo mechanosensitivity
2017 Nobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Light-Induced Subunit Dissociation by a Light–Oxygen–Voltage Domain Photoreceptor from Rhodobacter sphaeroides
2012
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Proton-Coupled Electron Transfer
2012 Standout
Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold
2022 Science
Works of Jason Key being referenced
Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules
2012
Photosensing in chemotrophic, non-phototrophic bacteria: let there be light sensing too
2007
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
2013
Extraction of accurate structure-factor amplitudes from Laue data: wavelength normalization with wiggler and undulator X-ray sources
2000
Purification and Initial Characterization of a Putative Blue Light Regulated Phosphodiesterase from Escherichia coli
2004
Collaboration gets the most out of software
2013
Purification and Initial Characterization of a Putative Blue Light–regulated Phosphodiesterase from Escherichia coli¶
2004
Structure of the Redox Sensor Domain of Azotobacter vinelandii NifL at Atomic Resolution: Signaling, Dimerization, and Mechanism,
2007
Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
2013
Hydrogen-bond switching through a radical pair mechanism in a flavin-binding photoreceptor
2006
Crystal Structures of Deoxy and CO-Bound bjFixLH Reveal Details of Ligand Recognition and Signaling
2005
Purification and Initial Characterization of a Putative Blue Light‐regulated Phosphodiesterase from Escherichia coli¶
2004
Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B
2009