Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
The Mammary Progenitor Marker CD61/β3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis
2008
Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
2008 StandoutScience
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
2010 Science
Hallmarks of Cancer: The Next Generation
2011 Standout
Activation of Wnt/β-catenin signalling pathway induces chemoresistance to interferon-α/5-fluorouracil combination therapy for hepatocellular carcinoma
2009
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Acute B lymphoblastic leukaemia‐propagating cells are present at high frequency in diverse lymphoblast populations
2012
2018
Thematic review series: Lipid Posttranslational Modifications. Farnesyl transferase inhibitors
2005
CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
2009
β-Catenin Mediates the Establishment and Drug Resistance of MLL Leukemic Stem Cells
2010
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
2008 Nature
JAK2 Exon 12 Mutations in Polycythemia Vera and Idiopathic Erythrocytosis
2007
Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy
2008
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
2010 Nature
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms
2014
Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues
2005
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9
2006 Nature
Neutrophilic leukocytosis in advanced stage polycythemia vera: hematopathologic features and prognostic implications
2015
Chronic myeloid leukaemia as a model of disease evolution in human cancer
2007
Enhanced MAPK signaling is essential for CSF3R-induced leukemia
2016
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized
2010
IgE and mast cells in allergic disease
2012 Standout
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
2007
Post-prenylation-processing enzymes as new targets in oncogenesis
2005
The changing landscape of atherosclerosis
2021 StandoutNature
Cancer stem cells in solid tumors
2007
The therapeutic promise of the cancer stem cell concept
2010
Rationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis
2015
Recent advances in cancer stem cells
2008
Ligand Independence of the T618I Mutation in the Colony-stimulating Factor 3 Receptor (CSF3R) Protein Results from Loss of O-Linked Glycosylation and Increased Receptor Dimerization
2014
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
2006
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia
2013
Loss of β-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo
2007
Angiogenesis in life, disease and medicine
2005 StandoutNature
An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms
2015
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Stems Cells and the Pathways to Aging and Cancer
2008
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
Antigens for cancer immunotherapy
2008
PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
2004
Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate
2010
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Cancer stem cells and oncology therapeutics
2006
Getting to the stem of chronic myeloid leukaemia
2008
Cancer immunotherapy comes of age
2011 StandoutNature
Essential thrombocythemia, polycythemia vera, and myelofibrosis: Current management and the prospect of targeted therapy
2008
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Chronic Eosinophilic Leukemias and the Myeloproliferative Variant of the Hypereosinophilic Syndrome
2007
ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth
2012
Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia
2008
Clonal evolution in cancer
2012 StandoutNature
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
2007 Standout
The Hallmarks of Aging
2013 Standout
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Chronic mast cell leukemia: A novel leukemia-variant with distinct morphological and clinical features
2014
Clonal Hematopoiesis
2019
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Bispecific antibodies: a mechanistic review of the pipeline
2019
Wnt signalling in stem cells and cancer
2005 StandoutNature
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
2010
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Requirement for CD44 in homing and engraftment of BCR-ABL–expressing leukemic stem cells
2006
Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells
2010
Cancer stem cells: an evolving concept
2012
The cancer genome
2009 StandoutNature
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Acute erythroid leukemia: a reassessment using criteria refined in the 2008 WHO classification
2009
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
2007
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Myelodysplastic Syndromes Clinical Practice Guidelines in Oncology
2006
Targeted CML therapy: controlling drug resistance, seeking cure
2005
Tumour stem cells and drug resistance
2005 Standout
Isolating gene-corrected stem cells without drug selection
2005 StandoutNobel
MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients
2006
ASXL1 mutations are frequent and prognostically detrimental in CSF3R‐mutated chronic neutrophilic leukemia
2015
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
2011
Overview of the Generation, Validation, and Application of Phosphosite-Specific Antibodies
2011
Hematopoietic Stem and Progenitor Cells: Clinical and Preclinical Regeneration of the Hematolymphoid System
2002
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Hypomethylating agent combination strategies in myelodysplastic syndromes: hopes and shortcomings
2016
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
2009 Standout
Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
2012
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals
2006
Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph + leukemia in mice
2006
Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study
2006
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Myeloproliferative neoplasms: Morphology and clinical practice
2015
Recent advances in understanding the molecular pathogenesis of myelodysplastic syndromes
2013
Cancer Stem Cells: An Old Idea—A Paradigm Shift
2006
A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas
2005
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
2016
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)
2010
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Stem cell concepts renew cancer research
2008
Diagnosis and management of mastocytosis: an emerging challenge in applied hematology
2015
Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation
2015 StandoutNobel
Genomics of chronic neutrophilic leukemia
2016
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
Leukemia stem cells in a genetically defined murine model of blast-crisis CML
2007
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
2007 Standout
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
2010
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
The Myeloproliferative Disorders
2006
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
The Biology of Cancer Stem Cells
2007
Chemical Glycoproteomics
2016 StandoutNobel
Works of Jason Gotlib being referenced
Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms
2016
The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I
2015
Myeloid neoplasms associated with eosinophilia and rearrangement of PDGFRA ,PDGFRB , and FGFR 1: a review
2013
Effect of treatment with a JAK2-selective inhibitor, fedratinib, on bone marrow fibrosis in patients with myelofibrosis
2015
OncogenicCSF3RMutations in Chronic Neutrophilic Leukemia and Atypical CML
2013
Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors
2008
Soluble TNF receptor fusion protein (etanercept) for the treatment of myelodysplastic syndrome: A pilot study
2002
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens
2009
LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
2010
Granulocyte–Macrophage Progenitors as Candidate Leukemic Stem Cells in Blast-Crisis CML
2004
Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
2005
RNAi screen for rapid therapeutic target identification in leukemia patients
2009
KIT Inhibitor Midostaurin in Patients with Advanced Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global CPKC412D2201 Trial
2012
Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation
2009
Selective Inhibition of JAK2 Driven Erythroid Differentiation of Polycythemia Vera Progenitors
2007
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
2010
A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
2006
Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system
2009
The FIP1L1-PDGFRα fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management
2003
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment
2013
Farnesyltransferase inhibitor therapy in acute myelogenous leukemia.
2005
Trispecific killer engager CD16xIL15xCD33 potently induces NK cell activation and cytotoxicity against neoplastic mast cells
2018
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation
2006
The Platelet-Derived Growth Factor Receptor beta Fuses to Two Distinct Loci at 3p21 in Imatinib Responsive Chronic Eosinophilic Leukemia.
2005
Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors
2008
Sequential azacitidine plus lenalidomide in previously treated elderly patients with acute myeloid leukemia and higher risk myelodysplastic syndrome
2015
A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia
2007