Standout Papers
- The cancer glycocalyx mechanically primes integrin-mediated growth and survival (2014)
- Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag (2012)
- Glycotherapy: New Advances Inspire a Reemergence of Glycans in Medicine (2013)
- Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag (2011)
- Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag (2012)
- Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion (2013)
Citation Impact
Citing Papers
Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell–Mediated Tumor Immunity
2018
Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment
2019
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Hydrazino-Pictet-Spengler Ligation as a Biocompatible Method for the Generation of Stable Protein Conjugates
2013
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
2023 Nobel
Targeted glycan degradation potentiates the anticancer immune response in vivo
2020 StandoutNobel
Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins
2018
Siglec-mediated regulation of immune cell function in disease
2014
An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis
2020 StandoutNobel
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Modulation of Siglec-7 Signaling Via In Situ-Created High-Affinity cis-Ligands
2021
Leveraging Formylglycine-Generating Enzyme for Production of Site-Specifically Modified Bioconjugates
2018
Altered Tumor-Cell Glycosylation Promotes Metastasis
2014
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
2016
Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation
2015
Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis
2015 StandoutNobel
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Advances in cell surface glycoengineering reveal biological function
2016
Physical biology of the cancer cell glycocalyx
2018
Biological roles of glycans
2016 Standout
Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics
2016
Revealing the human mucinome
2022 StandoutNobel
Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches
2015
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense
2014
A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells
2016 StandoutNobel
Gut microbiota, metabolites and host immunity
2016 Standout
Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation
2014
Site-specific chemical protein conjugation using genetically encoded aldehyde tags
2012 StandoutNobel
Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligands
2015
Lectin Galactoside-binding Soluble 3 Binding Protein (LGALS3BP) Is a Tumor-associated Immunomodulatory Ligand for CD33-related Siglecs
2014
Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo
2015 StandoutNobel
Integrins as biomechanical sensors of the microenvironment
2019
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
2012
Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
2016
Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx
2019 StandoutNobel
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Siglecs as Immune Cell Checkpoints in Disease
2020
Siglec receptors impact mammalian lifespan by modulating oxidative stress
2015
Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells
2018
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Structural Basis for Copper–Oxygen Mediated C−H Bond Activation by the Formylglycine‐Generating Enzyme
2017
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors
2017
Isotope Targeted Glycoproteomics (IsoTaG) to Characterize Intact, Metabolically Labeled Glycopeptides from Complex Proteomes
2016 StandoutNobel
Visualization of mycobacterial membrane dynamics in live cells
2017 StandoutNobel
O-linked mucin-type glycosylation in breast cancer
2018
Bioorthogonal Chemical Reporters for Selective In Situ Probing of Mycomembrane Components in Mycobacteria
2016
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer
2014
Viewing Siglecs through the lens of tumor immunology
2017
Enhanced Concanavalin A Binding to Preorganized Mannose Nanoarrays in Glycodendrimersomes Revealed Multivalent Interactions
2021
Targeted Delivery of a Sialic Acid-Blocking Glycomimetic to Cancer Cells Inhibits Metastatic Spread
2015
Sequence-Specific Mucins for Glycocalyx Engineering
2019
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
Tumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells
2016
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis
2016
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Targeted methods for quantitative analysis of protein glycosylation
2014
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation
2015 StandoutNobel
Formylglycine, a Post-Translationally Generated Residue with Unique Catalytic Capabilities and Biotechnology Applications
2014 StandoutNobel
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Identification of Siglec Ligands Using a Proximity Labeling Method
2017
Molecular imaging of biological systems with a clickable dye in the broad 800- to 1,700-nm near-infrared window
2017
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
2017 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis
2020 StandoutNobel
Sialic Acids Sweeten a Tumor's Life
2014
Orthogonal bioorthogonal chemistries
2015
Asking more from metabolic oligosaccharide engineering
2018
CalFluors: A Universal Motif for Fluorogenic Azide Probes across the Visible Spectrum
2015 StandoutNobel
In Vitro Reconstitution of Formylglycine‐Generating Enzymes Requires Copper(I)
2015
Steering Siglec–Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry
2017
Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared
2018 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Advances in Chemical Protein Modification
2015
Works of Jason E. Hudak being referenced
Active-Site-Directed Chemical Tools for Profiling Mitochondrial Lon Protease
2011
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion
2013 StandoutNobel
Glycotherapy: New Advances Inspire a Reemergence of Glycans in Medicine
2013 StandoutNobel
Illuminating vital surface molecules of symbionts in health and disease
2017
In vivo imaging and tracking of host–microbiota interactions via metabolic labeling of gut anaerobic bacteria
2015
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Identification of the Proteasome Inhibitor MG262 as a Potent ATP-Dependent Inhibitor of the Salmonella enterica serovar Typhimurium Lon Protease
2006
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel