Citation Impact
Citing Papers
DiarrheagenicEscherichia coli
1998 Standout
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
2013 Standout
Molecular Cloning and Functional Characterization of Psoralen Synthase, the First Committed Monooxygenase of Furanocoumarin Biosynthesis
2006
Evolutionary History of a Specialized P450 Propane Monooxygenase
2008 StandoutNobel
The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells
2008
Characterization of lipid and lipoprotein metabolism in primary human hepatocytes
2012
Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid
2016 StandoutNobel
Methods for Predicting Human Drug Metabolism
2006
Potential therapeutics for obesity and atherosclerosis: Inhibitors of neutral lipid metabolism from microorganisms
2007 StandoutNobel
Recapitulation of the hepatitis C virus life-cycle in engineered murine cell lines
2013 StandoutNobel
Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells
2009
Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis
2007
Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes
2009
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes
2003
Cell-based assays: fuelling drug discovery
2010
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
Organoid Models and Applications in Biomedical Research
2015 Standout
Nuclear receptor PXR, transcriptional circuits and metabolic relevance
2011
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
2008 Standout
Acid–base regulation in fishes: cellular and molecular mechanisms
2002
Immortal Activated Human Hepatic Stellate Cells Generated by Ectopic Telomerase Expression
2002
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
2001
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)
2008
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
2007
Gut microbiome and health: mechanistic insights
2022 Standout
Principles of early drug discovery
2010 Standout
Gut–brain axis: how the microbiome influences anxiety and depression
2013 Standout
Pathogenic Escherichia coli
2004 Standout
Chronic peripheral administration of corticotropin-releasing factor causes colonic barrier dysfunction similar to psychological stress
2008
Effect of ACAT Inhibition on the Progression of Coronary Atherosclerosis
2006
Organocatalytic Asymmetric Hydrolysis of Epoxides
2014 StandoutNobel
The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone MetabolismIn Vitro
2009
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2
2009
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Expression and Regulation of the Na+‐K+‐2Cl− Cotransporter NKCC1 in the Normal and CFTR‐Deficient Murine Colon
2003 StandoutNobel
The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste
2004 Standout
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
The Transcriptional Regulation of the Human CYP2C Genes
2009
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
Evolving concepts in liver tissue modeling and implications forin vitrotoxicology
2008
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases
2019 Standout
Evolution of the mammary gland from the innate immune system?
2006 StandoutNobel
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
REGULATION OF CYP2B6 IN PRIMARY HUMAN HEPATOCYTES BY PROTOTYPICAL INDUCERS
2004
Organotypic liver culture models: Meeting current challenges in toxicity testing
2012
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
A Novel Distal Enhancer Module Regulated by Pregnane X Receptor/Constitutive Androstane Receptor Is Essential for the Maximal Induction of CYP2B6 Gene Expression
2003
Applications of AmpliChip??? CYP450
2005
Rifampicin is only a weak inducer of CYP1A2-mediated presystemic and systemic metabolism: studies with tizanidine and caffeine
2006
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis
2000
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers
2006
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Inhibition of Acyl‐CoA Cholesterol Acyltransferase by F12511 (Eflucimibe): Could it be a New Antiatherosclerotic Therapeutic?
2008
Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes
2004
Expression and membrane localization of MCT isoforms along the length of the human intestine
2005
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells
2016 StandoutNobel
Pluripotent Stem Cell–Derived Hepatocytes: Potential and Challenges in Pharmacology
2013
Cholinergic ion secretion in human colon requires coactivation by cAMP
1998
Cytokinetic analysis of the impaired proliferative response of peripheral lymphocytes from aged humans to phytohemagglutinin.
1979
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
1996
Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions
2004
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Pyripyropene A, an Acyl–Coenzyme A:Cholesterol Acyltransferase 2–Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia
2011 StandoutNobel
The Many Roles for Fluorine in Medicinal Chemistry
2008 Standout
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
Broadly neutralizing antibodies abrogate established hepatitis C virus infection
2014 StandoutNobel
Enterotoxigenic Escherichia coli in Developing Countries: Epidemiology, Microbiology, Clinical Features, Treatment, and Prevention
2005 Standout
Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers
2013 StandoutNobel
In vitro evaluation of the inhibition and induction potential of olaparib, a potent poly(ADP-ribose) polymerase inhibitor, on cytochrome P450
2017
Augmentation of Myocardial Production of 15-Epi-Lipoxin-A 4 by Pioglitazone and Atorvastatin in the Rat
2006
Regulation of intestinal Cl−and HCO 3 − secretion by uroguanylin
1998
Impaired nuclear responsiveness to cytoplasmic signals in lymphocytes from elderly humans with depressed proliferative responses.
1986 StandoutNobel
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Enterochromaffin-Like Cells, a Cellular Source of Uroguanylin in Rat Stomach*
1999
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Janus Kinase 2 (JAK2) Regulates Prolactin-Mediated Chloride Transport in Mouse Mammary Epithelial Cells through Tyrosine Phosphorylation of Na+-K+-2Cl− Cotransporter
2000
Towards a small animal model for hepatitis C
2009 StandoutNobel
Preclinical experimental models of drug metabolism and disposition in drug discovery and development
2012
Total synthesis of pyripyropene A
2011 StandoutNobel
Lung Infections Associated with Cystic Fibrosis
2002 Standout
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Cytochrome P450 and Chemical Toxicology
2007
Works of Jasminder Sahi being referenced
Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical
2008
Calcium regulated chloride permeabilities in primary cultures of rabbit colonocytes
1996
Avasimibe Induces CYP3A4 and Multiple Drug Resistance Protein 1 Gene Expression through Activation of the Pregnane X Receptor
2003
Hepatocytes as a Tool in Drug Metabolism, Transport and Safety Evaluations in Drug Discovery
2010
Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes
2000
EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO
2004
Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization
2001
Chloride transport in primary cultures of rabbit colonocytes at different stages of development
1996
Effects of Bergamottin on Human and Monkey Drug-Metabolizing Enzymes in Primary Cultured Hepatocytes
2002
Escherichia coli heat-stable enterotoxin-mediated colonic Cl− secretion is absent in cystic fibrosis
1994
Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line
2004
Comparative Effects of Thiazolidinediones on in Vitro P450 Enzyme Induction and Inhibition
2003
A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes
2012
Cl− transport in an immortalized human epithelial cell line (NCM460) derived from the normal transverse colon
1998
Use ofin vitrotransporter assays to understand hepatic and renal disposition of new drug candidates
2005
[Reactivity of lymphocytes in the aged].
1971
In vitro ADME phenotyping in drug discovery: current challenges and future solutions.
2005
Hepatobiliary Disposition in Primary Cultures of Dog and Monkey Hepatocytes
2006
Cyclic AMP- and phorbol ester-regulated Cl- permeabilities in primary cultures of human and rabbit colonocytes
1994