Citation Impact
Citing Papers
Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
2008
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer
2003
Regulation of the breast cancer stem cell phenotype by hypoxia-inducible factors
2015 StandoutNobel
Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17
2005
Structure of the Ubiquitin Hydrolase UCH-L3 Complexed with a Suicide Substrate
2004
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with β-catenin
2003
An overview of enzymatic reagents for the removal of affinity tags
2011
The Deubiquitinating Enzyme USP1 Regulates the Fanconi Anemia Pathway
2005
MAPK pathway contributes to density- and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX
2005
Targeting hypoxia in cancer therapy
2011 Standout
Regulation of cancer cell metabolism by hypoxia-inducible factor 1
2008 StandoutNobel
DNA recognition by an RNA-guided bacterial Argonaute
2017 StandoutNobel
Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients
2003
Tumor Cell Metabolism: Cancer's Achilles' Heel
2008 Standout
Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma
2007 Standout
Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use
2014
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Targeting tumor-associated carbonic anhydrase IX in cancer therapy
2006
Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
2007 Standout
Lessons from 60 years of pharmaceutical innovation
2009 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Recombinant protein expression in Escherichia coli: advances and challenges
2014 Standout
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
2010 Nature
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
Novel approaches in the therapy of metastatic renal cell carcinoma
2005
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
2008 Standout
Caspase Substrates and Inhibitors
2013
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Hypoxia activates the capacity of tumor‐associated carbonic anhydrase IX to acidify extracellular pH
2004
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2
2005
Dysregulated pH: a perfect storm for cancer progression
2011 Standout
Molecular mechanisms of carbonic anhydrase IX‐mediated pH regulation under hypoxia
2008 StandoutNobel
Structural Basis for the Specificity and Catalysis of Human Atg4B Responsible for Mammalian Autophagy
2005 StandoutNobel
Carbonic Anhydrase IX: Regulation and Role in Cancer
2013
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
2020 Standout
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
2010 StandoutScience
Evaluation of HIF-1 inhibitors as anticancer agents
2007 StandoutNobel
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
2016
Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
2014 StandoutNobel
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
2013
Distributed Drug Discovery, Part 1: Linking Academia and Combinatorial Chemistry to Find Drug Leads for Developing World Diseases
2008
Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway.
2003
Role of Hypoxia-Inducible Factors in Breast Cancer Metastasis
2013 StandoutNobel
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
Combination therapy in combating cancer
2017 Standout
Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide‐rich de novo designed peptides
2018 StandoutNobel
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
2009
Role of Carbonic Anhydrase IX in Human Tumor Cell Growth, Survival, and Invasion
2004
Tumor‐associated Carbonic Anhydrases and Their Clinical Significance
2006
Indanesulfonamides as Carbonic Anhydrase Inhibitors. Toward Structure-Based Design of Selective Inhibitors of the Tumor-Associated Isozyme CA IX
2006
The Ubiquitin Code
2012 Standout
HIF‐1α and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome
2007
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Jared Ek being referenced
Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion
2000
Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials
2010
A strategy to profile prime and non-prime proteolytic substrate specificity
2005
Substrate Profiling of Deubiquitin Hydrolases with a Positional Scanning Library and Mass Spectrometry
2004
Purifying the Masses: Integrating Prepurification Quality Control, High-Throughput LC/MS Purification, and Compound Plating To Feed High-Throughput Screening
2005