Janelle M. Wright

Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity

A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia

Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis

The efficacy of an oral treatment with paromomycin against an experimental infection with Giardia in calves

Analysis of nucleotide variation within the triose‐phosphate isomerase gene of Giardia duodenalis from sheep and its zoonotic implications

Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia

4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum

Microvesicles and intercellular communication in the context of parasitism

Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2)

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

Persistent and recurrentTrichomonas vaginalisinfections: epidemiology, treatment and management considerations

Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds

Characterization, Kinetics, and Crystal Structures of Fructose-1,6-bisphosphate Aldolase from the Human Parasite, Giardia lamblia

Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole

A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro

Validation of in-vitro bioassay methods: Application in herbal drug research

Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia

Zoonotic Potential and Molecular Epidemiology ofGiardiaSpecies and Giardiasis

Sexually Transmitted Infections Treatment Guidelines, 2021

Hsp90 Inhibitors as New Leads To Target Parasitic Diarrheal Diseases

Symptomatic Trichomonas vaginalis infection in the setting of severe nitroimidazole allergy: successful treatment with boric acid

Sexually Transmitted Diseases Treatment Guidelines, 2010

Synthesis and Electrochemistry of 2-Ethenyl and 2-Ethanyl Derivatives of 5-Nitroimidazole and Antimicrobial Activity against Giardia lamblia

Impaired Parasite Attachment as Fitness Cost of Metronidazole Resistance in Giardia lamblia

Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia

Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia

The biology , function , and biomedical applications of exosomes

Extracellular vesicles in parasitic diseases

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

Exploring the Fasciola hepatica tegument proteome

Susceptibility in vitro of clinically metronidazole-resistant Trichomonas vaginalis to nitazoxanide, toyocamycin, and 2-fluoro-2′-deoxyadenosine

The activity of protease inhibitors against Giardia duodenalis and metronidazole-resistant Trichomonas vaginalis

Hydrogenosomes of Laboratory‐Induced Metronidazole‐Resistant Trichomonas vaginalis Lines are Downsized While Those from Clinically Metronidazole‐Resistant Isolates Are Not

Efficacy of antigiardial drugs

5-Nitroimidazole Drugs Effective against Metronidazole-Resistant Trichomonas vaginalis and Giardia duodenalis