Citation Impact
Citing Papers
Physical Activity and Public Health
2007 Standout
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
Tumor-targeting peptides from combinatorial libraries
2016
Making new contacts: the mTOR network in metabolism and signalling crosstalk
2014
mTOR Signaling in Growth Control and Disease
2012 Standout
The Tuberous Sclerosis Complex
2006 Standout
mTOR and autophagy: A dynamic relationship governed by nutrients and energy
2014
Exercise Type and Intensity in Relation to Coronary Heart Disease in Men
2002
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Genotype/phenotype correlation in 325 individuals referred for a diagnosis of tuberous sclerosis complex in the United States
2007
Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease
2005
Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells
2016
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer
2016
Cell Cycle-regulated Phosphorylation of Hamartin, the Product of the Tuberous Sclerosis Complex 1 Gene, by Cyclin-dependent Kinase 1/Cyclin B
2003
Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary Report
2007 Standout
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Tuberin Regulates p70 S6 Kinase Activation and Ribosomal Protein S6 Phosphorylation
2002
Hallmarks of aging: An expanding universe
2023 Standout
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
2003 Standout
Plasma Adiponectin Levels and Risk of Myocardial Infarction in Men
2004 Standout
Rapamycin: One Drug, Many Effects
2014 Standout
SIRT5 regulation of ammonia-induced autophagy and mitophagy
2015
Renal angiomyolipomata
2004
The multifaceted functions of sirtuins in cancer
2015
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis
2008 Standout
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
2017
Mutational analysis of the TSC1 and TSC2 genes in a diagnostic setting: genotype – phenotype correlations and comparison of diagnostic DNA techniques in Tuberous Sclerosis Complex
2005
Sirtuins and the Metabolic Hurdles in Cancer
2015
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Physical Activity and Television Watching in Relation to Risk for Type 2 Diabetes Mellitus in Men
2001
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
Lymphangioleiomyomatosis — a wolf in sheep’s clothing
2012
Deconvoluting the context-dependent role for autophagy in cancer
2012
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
2012
Autophagy in Human Health and Disease
2013 Standout
Tuberous sclerosis
2008 Standout
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration
2002
Pathogenesis of Tuberous Sclerosis Subependymal Giant Cell Astrocytomas: Biallelic Inactivation ofTSC1orTSC2Leads to mTOR Activation
2004
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
Embolization of Renal Angiomyolipomata in Patients With Tuberous Sclerosis Complex
2005
Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review
2020
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway
2009
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
COVID-19: consider cytokine storm syndromes and immunosuppression
2020 Standout
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part A: Renal, Penile, and Testicular Tumours
2016 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
A Study of Sexuality and Health among Older Adults in the United States
2007 Standout
Regulation of B-Raf Kinase Activity by Tuberin and Rheb Is Mammalian Target of Rapamycin (mTOR)-independent
2004
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
The PI3K Pathway in Human Disease
2017 Standout
A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome
2017
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
2012
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
2020 Standout
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Television Watching and Other Sedentary Behaviors in Relation to Risk of Obesity and Type 2 Diabetes Mellitus in Women
2003 Standout
Alternative splicing in aging and longevity
2019
Recurrent Lymphangiomyomatosis after Transplantation
2003
Modulation of Cell Migration and Invasiveness by Tumor Suppressor TSC2 in Lymphangioleiomyomatosis
2005
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
2014
The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
2004 Standout
Coactivator SRC-2–dependent metabolic reprogramming mediates prostate cancer survival and metastasis
2015
Lymphatic vascular morphogenesis in development, physiology, and disease
2011
Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
2016
Reproducibility of Metabolomic Profiles among Men and Women in 2 Large Cohort Studies
2013
Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
2015
Tuberous sclerosis
2006
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
2015
Exercise type and intensity in relation to coronary heart disease in men
2003
Recommendations for Treatment of Child and Adolescent Overweight and Obesity
2007
Autophagy in Idiopathic Pulmonary Fibrosis
2012
Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi
2015
Metabolic reprogramming and cancer progression
2020 StandoutScience
The TSC1–TSC2 complex: a molecular switchboard controlling cell growth
2008 Standout
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex
2014
Trends in Obesity Prevalence Among Children and Adolescents in the United States, 1988-1994 Through 2013-2014
2016 Standout
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment
2015
New developments in the genetics and pathogenesis of tumours in tuberous sclerosis complex
2016
Sexual Function in Men Older Than 50 Years of Age: Results from the Health Professionals Follow-up Study
2003
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Works of Jane Yu being referenced
Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide
2013
Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent
2011
High-Throughput Drug Screen Identifies Chelerythrine as a Selective Inducer of Death in a TSC2-null Setting
2014
Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells
2009
IL‐10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF‐κB/Notch1 pathway in non‐small cell lung cancer
2019
mTOR Activation, Lymphangiogenesis, and Estrogen-Mediated Cell Survival: The “Perfect Storm” of Pro-Metastatic Factors in LAM Pathogenesis
2010
Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus
2016
The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development
2010
Renal Cell Carcinoma in Tuberous Sclerosis Complex
2014
The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4
2013
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
2017
Leisure-Time Physical Activity, Television Watching, and Plasma Biomarkers of Obesity and Cardiovascular Disease Risk
2000
Plasma leptin concentrations and four-year weight gain among US men
2001
Renal Angiomyolipomas from Patients with Sporadic Lymphangiomyomatosis Contain Both Neoplastic and Non-Neoplastic Vascular Structures
2003
Phage display discovery of novel molecular targets in glioblastoma-initiating cells
2014
Autophagy
2011
Mammalian Target of Rapamycin Signaling and Autophagy: Roles in Lymphangioleiomyomatosis Therapy
2010
Chromosome 16 Loss of Heterozygosity in Tuberous Sclerosis and Sporadic Lymphangiomyomatosis
2001
Tuberous Sclerosis Complex 2 Loss Increases Lysophosphatidylcholine Synthesis in Lymphangioleiomyomatosis
2015
Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways
2004