Citation Impact
Citing Papers
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
2008 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management
2002
Hallmarks of Cancer: The Next Generation
2011 Standout
Polymorphisms in Glutathione S-Transferases are Associated with Altered Risk of Nonmelanoma Skin Cancer in Renal Transplant Recipients: A Preliminary Analysis
2001
Physical Interaction with Human Tumor-derived p53 Mutants Inhibits p63 Activities
2002
The accuracy of clinical diagnosis of suspected premalignant and malignant skin lesions in renal transplant recipients
2002
Non-melanoma skin cancer risk in the Queensland renal transplant population
2002
Comparative epidemiologic study of premalignant and malignant epithelial cutaneous lesions developing after kidney and heart transplantation
1995
Chemosensitivity linked to p73 function
2003 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
Transcriptional regulation by p53: one protein, many possibilities
2006
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
2009 Standout
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
p53 polymorphisms: cancer implications
2009
Functional regulation of p73 and p63: development and cancer
2003
Global Cancer Statistics, 2002
2005 Standout
Oncogenic kinase signalling
2001 StandoutNature
Somatic Hypermutation, Transcription, and DNA Mismatch Repair
1998
The Genetics of Sun Sensitivity in Humans
2004
Cancer after Kidney Transplantation in the United States
2004
A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response
2010 Standout
E2F-1 induced apoptosis
2001
p53 codon 72 polymorphism and its association with bladder cancer
2002
Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73
2003
Use of thiopurines in inflammatory bowel disease: Safety issues
2014
p73 is transcriptionally regulated by DNA damage, p53, and p73
2001
Single-nucleotide Polymorphisms in the p53 Signaling Pathway
2009
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72
2007
Quadrivalent Vaccine against Human Papillomavirus to Prevent Anogenital Diseases
2007 Standout
Skin Cancers after Organ Transplantation
2003 Standout
TdT-Accessible Breaks Are Scattered over the Immunoglobulin V Domain in a Constitutively Hypermutating B Cell Line
1998
Skin cancer in kidney and heart transplant recipients and different long-term immunosuppressive therapy regimens
1999
Mismatch Repair Deficiency Interferes with the Accumulation of Mutations in Chronically Stimulated B Cells and Not with the Hypermutation Process
1998
Transactivation-deficient ΔTA-p73 Inhibits p53 by Direct Competition for DNA Binding
2002
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome
2004
Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer
2005 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP
2005 Standout
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
The dark side of a tumor suppressor: anti-apoptotic p53
2008
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional Activity
2001
The causal relation between human papillomavirus and cervical cancer
2002 Standout
p53 codon 72 Pro homozygosity increases the risk of cutaneous melanoma in individuals with dark skin complexion and among noncarriers of melanocortin 1 receptor red hair variants
2006
TP53 mutation, allelism and survival in non-small cell lung cancer
2005
p63 and p73: p53 mimics, menaces and more
2000
Reactivation of mutant p53: molecular mechanisms and therapeutic potential
2007
Apoptosis
2002 Standout
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Common Polymorphisms in the MDM2 and TP53 Genes and the Relationship between TP53 Mutations and Patient Outcomes in Glioblastomas
2008
Live or let die: the cell's response to p53
2002 Standout
Somatic Hypermutation of Immunoglobulin Genes is Linked to Transcription
1998
Renal allograft recipients with high susceptibility to cutaneous malignancy have an increased prevalence of human papillomavirus DNA in skin tumours and a greater risk of anogenital malignancy
1997
Polymorphisms in the p53 pathway
2006
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Defying Ring Strain: New Approaches to Cyclopropanes
2009
Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool
2001
Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in theTP53gene on survival in patients with advanced ovarian carcinoma
2004
p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis
2003
Requirement of clathrin heavy chain for p53-mediated transcription
2006
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
2007
Catalytic Asymmetric Synthesis of Phosphine Boronates
2015 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
A Boron‐Based Synthesis of the Natural Product (+)‐trans‐Dihydrolycoricidine
2011
Role of the newer p53 family proteins in malignancy
2001 StandoutNobel
Mutant p53 Gain-of-Function in Cancer
2009
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
The p53 pathway: positive and negative feedback loops
2005 Standout
Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins
2000
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
The genetics of the p53 pathway, apoptosis and cancer therapy
2008
Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease
2013 Standout
Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
2003 Standout
TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis
2003
TP53 Polymorphism of Exon 4 at Codon 72 in Cutaneous Squamous Cell Carcinoma and Benign Epithelial Lesions of Renal Transplant Recipients and Immunocompetent Individuals: Lack of Correlation with Human Papillomavirus Status11This work was presented in part at the 19th International Papillomavirus Conference in Florianopolis, Brazil, September 1–7, 2001.
2002
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Comparison of the Differential Context-dependence of DNA Deamination by APOBEC Enzymes: Correlation with Mutation Spectra in Vivo
2004
p73: Friend or foe in tumorigenesis
2002
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Retention of the p53 codon 72 arginine allele is associated with a reduction of disease-free and overall survival in arginine/proline heterozygous breast cancer patients.
2003
Lanthanum(III) Triflate-Catalyzed Cyclopropanation via Intramolecular Methylene Transfer
2009
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
ΔNp73, A Dominant-Negative Inhibitor of Wild-type p53 and TAp73, Is Up-regulated in Human Tumors
2002
Human Transcriptome Subtraction by Using Short Sequence Tags To Search for Tumor Viruses in Conjunctival Carcinoma
2007
Transcription, β–like DNA polymerases and hypermutation
2001
Both DNA strands of antibody genes are hypermutation targets
1998 Nobel
Preferential retention of codon 72 arginine p53 in squamous cell carcinomas of the vulva occurs in cancers positive and negative for human papillomavirus.
2000 StandoutNobel
Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora
2002 StandoutScienceNobel
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2
1998
Hypermutation of Immunoglobulin Genes in Memory B Cells of DNA Repair–deficient Mice
1998
Persistence of Human Papillomavirus DNA in Benign and (Pre)malignant Skin Lesions from Renal Transplant Recipients
2000
Role of the p53-homologue p73 in E2F1-induced apoptosis
2000
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Cancer incidence and risk factors after solid organ transplantation
2009
Defect in IgV gene somatic hypermutation in Common Variable Immuno-Deficiency syndrome
1998
A Hypermutable Insert in an Immunoglobulin Transgene Contains Hotspots of Somatic Mutation and Sequences Predicting Highly Stable Structures in the RNA Transcript
1998
Cis‐acting sequences that affect somatic hypermutation of Ig genes
1998
A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain
2001
THE PREVALENCE OF HUMAN PAPILLOMAVIRUS DNA IN BENIGN KERATOTIC SKIN LESIONS OF RENAL TRANSPLANT RECIPIENTS WITH AND WITHOUT A HISTORY OF SKIN CANCER IS EQUALLY HIGH: A CLINICAL STUDY TO ASSESS RISK FACTORS FOR KERATOTIC SKIN LESIONS AND SKIN CANCER 1
2000
Constitutive Expression of AID Leads to Tumorigenesis
2003 StandoutNobel
A Boron‐Based Synthesis of the Natural Product (+)‐trans‐Dihydrolycoricidine
2011
Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.
2000
p53 family update: p73 and p63 develop their own identities.
2001 StandoutNobel
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
DNA Double-Strand Breaks
2002 StandoutNobel
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Evaluation of the Combined Effect of p53 Codon 72 Polymorphism and Hotspot Mutations in Response to Anticancer Drugs
2005
Different Mismatch Repair Deficiencies All Have the Same Effects on Somatic Hypermutation
1999
Quantitative Regulation of Class Switch Recombination by Switch Region Transcription
2001 StandoutNobel
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
Activation-induced Deaminase (AID)-directed Hypermutation in the Immunoglobulin Sμ Region
2002 StandoutNobel
Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73.
2002
The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas.
2002
Works of Jane McGregor being referenced
Posttransplant skin cancer: A possible role for p53 gene mutation but not for oncogenic human papillomaviruses
1994
Virus infection and cancer risk in transplant recipients
1996
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
2000 StandoutNobel
Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals
2000
p53 mutations implicate sunlight in post-transplant skin cancer irrespective of human papillomarivus status
1997
Somatic hypermutation of Ig genes in patients with xeroderma pigmentosum (XP-D)
1996
Detection of Human Papillomavirus DNA in PUVA-Associated Non-Melanoma Skin Cancers
1998
Relationship Between p53 Codon 72 Polymorphism and Susceptibility to Sunburn and Skin Cancer
2002
A sequential stereocontrolled cyclopropane ring formation and semi-pinacol rearrangement
2003
Azathioprine and UVA Light Generate Mutagenic Oxidative DNA Damage
2005 Science
Human papillomavirus and skin cancer
1994
Degenerate and Nested PCR: a Highly Sensitive and Specific Method for Detection of Human Papillomavirus Infection in Cutaneous Warts
1999
Isolation and Structural Modification of 7-Deoxynarciclasine and 7-Deoxy-trans-Dihydronarciclasine,1
2005