Standout Papers
Citation Impact
Citing Papers
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection
1974
Proteins regulating Ras and its relatives
1993 StandoutNature
Rasburicase (recombinant urate oxidase) for the management of hyperuricemia in patients with cancer
2003
A concomitant ATP-depleting strategy markedly enhances anticancer agent activity
2001
National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications
2012 Standout
Metabolism and action of amino acid analog anti-cancer agents
1990
Cloning and Characterization of Human Guanine Deaminase
1999
Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour
2009
Tumor lysis syndrome
2001
Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect
2016 Standout
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Elitek™–rasburicase: an effective means to prevent and treat hyperuricemia associated with tumor lysis syndrome, a Meeting Report, Dallas, Texas, January 2002
2003
Recombinant urate oxidase (rasburicase) in the prevention and treatment of malignancy-associated hyperuricemia in pediatric and adult patients: results of a compassionate-use trial
2001
Inhibitors and activators of ADP-ribosylation reactions
1994
Acute tumor lysis syndrome in patients with high-grade non-Hodgkin's lymphoma
1993
Nucleoside and nucleobase transport in animal cells
1988
Mutation rates differ among regions of the mammalian genome
1989 StandoutNature
Regulation of the mevalonate pathway
1990 StandoutNature
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
1988 StandoutNature
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
2000 StandoutNature
Efficacy and safety of rasburicase, a recombinant urate oxidase (Elitek™), in the management of malignancy-associated hyperuricemia in pediatric and adult patients: final results of a multicenter compassionate use trial
2004
Effect of Extracellular AMP on Cell Proliferation and Metabolism of Breast Cancer Cell Lines with High and Low Glycolytic Rates
1997
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion
1998
WHO systematic review of randomised controlled trials of routine antenatal care
2001
Molecular and biochemical features of poly (ADP-ribose) metabolism
1993
Tumor lysis syndrome: pathogenesis and management
1995
Patterns of routine antenatal care for low-risk pregnancy
2001
WHO antenatal care randomised trial for the evaluation of a new model of routine antenatal care
2001 Standout
Tumour lysis syndrome: new therapeutic strategies and classification
2004 Standout
Cytochrome c
1966
Partial phenotypic correction of human Lesch-Nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector.
1984
Studies on glutathione S-alkyltransferase of the rat
1966
Availability of 5-Phosphoribosyl 1-Pyrophosphate for Ribonucleotide Synthesis in Ehrlich Ascites Tumor Cells in Vitro
1965
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
8-AZAGUANINE RESISTANCE IN MAMMALIAN CELLS I. HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE
1972
Urinary-Tract Stones Resulting from the Excretion of Oxypurinol
1975
Improved methods for the study of drug effects on purine metabolism and their application to nebularine and 7-deazanebularine
1974
Simple model for hormone-activated adenylate cyclase systems.
1976 StandoutNobel
Inhibition of cell growth and of purine biosynthesis by allopurinol and 4-aminopyrazolo(3,4-d)pyrimidine— a comparative study
1974
Mechanism of allopurinol-mediated increase in enzyme activity in man
1972
Effect of allopurinol and oxipurinol on pyrimidine synthesis in cultured human fibroblasts
1971
Role of antimetabolites in immunosuppression and transplantation
1969 StandoutNobel
Altering Genotype and Phenotype by DNA-Mediated Gene Transfer
1980 StandoutScienceNobel
Regulation of sterol synthesis in 15 tissues of rat. II. Role of rat and human high and low density plasma lipoproteins and of rat chylomicron remnants.
1977
A possible nucleotide-binding domain in the tertiary fold of phosphoribosyltransferases.
1983
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
The Role of Lipoproteins in Steroidogenesis and Cholesterol Metabolism in Steroidogenic Glands*
1982
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Some effects of 4-aminopyrazolo(3:4-d)pyrimidine on purine metabolism
1962
Glutathione S-Transferases
1974 Standout
Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells
1973 StandoutNobel
Activity and Mechanism of Action of 6-Methylthiopurine Ribonucleoside in Cancer Cells Resistant to 6-Mercaptopurine
1965 Nature
Regulation of sterol synthesis in adrenal gland of the rat by both high and low density human plasma lipoproteins
1976
Purification of Adenine Phosphoribosyltransferase by Affinity Chromatography
1978
Femtosecond dynamics of the DNA intercalator ethidium and electron transfer with mononucleotides in water
1999 StandoutNobel
DNA precursor pools and ribonucleotide reductase activity: distribution between the nucleus and cytoplasm of mammalian cells.
1985
Guidelines for the Management of Pediatric and Adult Tumor Lysis Syndrome: An Evidence-Based Review
2008 Standout
Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism.
1983
Carcinogens, Enzyme Induction, and Gene Action
1967
Metal and metal-ATP interactions with brain and cardiac adenylate cyclases.
1975
Ion-exchange chromatography of tissue nucleotides
1969
Recombinant Urate Oxidase for the Prophylaxis or Treatment of Hyperuricemia in Patients With Leukemia or Lymphoma
2001
Regulation of Plasma Cholesterol by Lipoprotein Receptors
1981 StandoutScienceNobel
An Enzymatic Basis for Variation in Response to Allopurinol
1968
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
1986 StandoutNature
Expression of Two X-Linked Genes in Human Hair Follicles of Double Heterozygotes
1971 StandoutNobel
Mechanism of allopurinol-mediated inhibition of pyrimidine biosynthesis.
1971
Reversal of the growth inhibitory effects of 6-methylthiopurine ribonucleoside
1970
The ras oncogene--an important regulatory element in lower eucaryotic organisms
1989
Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat.
1976 StandoutNobel
Postchemotherapy purine excretion in lymphoma patients receiving allopurinol.
1981
EFFECT OF ALLOPURINOL ON PYRIMIDINE METABOLISM IN THE LESCH-NYHAN SYNDROME
1970
A Receptor-Mediated Pathway for Cholesterol Homeostasis
1986 StandoutScienceNobel
The Clonal Evolution of Tumor Cell Populations
1976 StandoutScience
Formation of nucleotides of [6-14C]allopurinol and [6-14C]oxipurinol in rat tissues and effects on uridine nucleotide pools
1973 StandoutNobel
Single-allele expression at an X-linked hyperuricemia locus in heterozygous human cells.
1968
Formation of 5′-nucleotides of 6-methylmercaptopurine ribonucleoside in human tissues in vitro
1974 StandoutNobel
Guanine phosphoribosyltransferase from Escherichia coli. Specificity and properties
1972 StandoutNobel
Metabolism of pyrazolo(3,4-d)pyrimidines in Leishmania braziliensis and Leishmania donovani. Allopurinol, oxipurinol, and 4-aminopyrazolo(3,4-d)pyrimidine.
1979 StandoutNobel
Expression of a Bacterial Gene in Mammalian Cells
1980 StandoutScienceNobel
An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication
1972 StandoutNobel
Biochemical mechanisms for the synergism between 6-thioguanine and 6-(methylmercapto)purine ribonucleoside in sarcoma 180 cells.
1972
X-Linked Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency: Heterozygote Has Two Clonal Populations
1968 Science
The effect of 4-aminopyrazolo(3,4-d)pyrimidine and guanine on ehrlich ascites cells in culture
1967
Human Hypoxanthine Phosphoribosyltransferase
1969 StandoutNobel
Complex formation between ethidium bromide and nucleic acids
1965
Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
1996 StandoutScience
HIGH-RESOLUTION PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY OF CYTOCHROME c
1969 StandoutNobel
A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice
1987 StandoutNatureNobel
Depletion of Erythrocyte Phosphoribosylpyrophosphate in Man
1970
Receptor-Mediated Uptake of Lipoprotein-Cholesterol and Its Utilization for Steroid Synthesis in the Adrenal Cortex
1979 StandoutNobel
Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency: Activity in Normal, Mutant, and Heterozygote-Cultured Human Skin Fibroblasts
1970
ATP depletion + pyrimidine depletion can markedly enhance cancer therapy: fresh insight for a new approach.
2000
Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs
1973
Effects of high sucrose diets and 4-aminopyrazolopyrimidine on serum lipids and lipoproteins in the rat
1971
X-linked hypoxanthine-guanine phosphoribosyl transferase deficiency: Detection of heterozygotes by selective medium
1970
cDNA cloning of the bovine low density lipoprotein receptor: feedback regulation of a receptor mRNA.
1983 StandoutNobel
Preterm labor: One syndrome, many causes
2014 StandoutScience
HPRT: GENE STRUCTURE, EXPRESSION, AND MUTATION
1985
Molecular analysis of spontaneous somatic mutants
1977 StandoutNatureNobel
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Urate-oxidase prophylaxis of uric acid-induced renal damage in childhood leukemia
1982
Purine Metabolism in Human and Chicken Blood, in Vitro
1960
Acute tumor lysis syndrome
1980
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
Purine excretion during tumor lysis in children with acute lymphocytic leukemia receiving allopurinol: Relationship to acute renal failure
1986
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Distribution of purine ribonucleoside kinase and selectivet oxicity of 6-methylthiopurine ribonucleoside
1968
Lesch-Nyhan Syndrome: Rapid Detection of Heterozygotes by Use of Hair Follicles
1971 StandoutScienceNobel
Xanthine phosphoribosyltransferase from Streptococcus faecalis
1974 StandoutNobel
Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat.
1977 StandoutNobel
Cholesterogenesis: Derepression in Extrahepatic Tissues with 4-Aminopyrazolo [3,4- d ]pyrimidine
1976 Science
Isolation of transforming DNA: Cloning the hamster aprt gene
1980 StandoutNobel
Studies on the coordinate activity and lability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administration
1971
Works of Jane Henderson being referenced
Effects of 4-aminopyrazolo (3,4-d)pyrimidine and 1-methyl-4-aminopyrazolo(3,4-d)pyrimidine on nucleic acid purine metabolism in ascites tumors.
1961
The metabolism of 4-aminopyrazolo(3,4-d)pyrimidine in normal and neoplastic tissues.
1961
Studies on fatty liver induction by 4-aminopyrazolopyrimidine
1963
The role of support and other factors in early breastfeeding cessation: an analysis of data from a maternity survey in England
2014
Pushing the boundaries of viability: The economic impact of extreme preterm birth
2006
An Economic Evaluation Comparing Two Schedules of Antenatal Visits
2000
On the relationship between lipid solubility and microsomal metabolism of drugs
1965
The Impact of Preterm Birth on Hospital Inpatient Admissions and Costs During the First 5 Years of Life
2003
LYON HYPOTHESIS AND X-LINKED DISEASE
1967
Studies of the induction of microsomal S-, N- and O-demethylases
1964
Decreased feedback inhibition in a 6-(methylmercapto)purine ribonucleoside-resistant tumor.
1967
Inhibition of ascites tumor growth by 4-aminopyrazolo-(3,4-d)pyrimidine in combination with azaserine, 6-mercaptopurine, and thioguanine.
1960
Inhibition of glycolysis in Ehrlich ascites tumor cells incubated with formimino-L -glutamate
1969
Regulation of purine biosynthesis
1972
Inhibitors of hypoxanthine-guanine phosphoribosyltransferase.
1972
Properties of Adenyl Cyclase from Ehrlich Ascites Cells
1972
Regulation of ribonucleotide reduction by deoxyribonucleotides in intact Chinese hamster ovary cells
1981
Observations on the action of azaserine in mammalian tissues.
1957
Purine Biosynthesis de Novo in Mouse Tissues and a Mouse Tumor
1959
Hypoxanthine–guanine phosphoribosyltransferase: further evidence for the identity of the binding sites for hypoxanthine and guanine
1969
THE ENZYMIC FORMATION OF 6-(METHYLMERCAPTO)PURINE RIBONUCLEOSIDE 5′-PHOSPHATE
1966
Demethylation of purine analogs by microsomal enzymes from mouse liver
1964
Studies of the Binding of Phosphoribosyl Pyrophosphate to Adenine Phosphoribosyltransferase
1970
Kinetic Studies of Adenosine Kinase from Ehrlich Ascites Tumor Cells
1972
A specific enzyme defect in gout associated with overproduction of uric acid.
1967
Adenine phosphoribosyltransferase deficiency: a previously undescribed genetic defect in man
1968
Comparison of purine and pyrimidine metabolism in G1 and S phases of HeLa and Chinese hamster ovary cells
1982
Nitrobenzylthioinosine: an in vivo inhibitor of pig erythrocyte energy metabolism
1986
Inhibition of purine nucleotide metabolism by 6-methylthiopurine ribonucleoside and structurally related compounds.
1973
Kinetic studies of mutant human erythrocyte adenine phosphoribosyltransferases
1968
Xanthine Nephropathy in a Patient with Lymphosarcoma Treated with Allopurinol
1970
Transport of Adenine-8-C14 among Mouse Tissues by Blood Cells
1959
Feedback inhibition of purine biosynthesis in ascites tumor cells by purine analogues
1963
Xanthine phosphoribosyltransferase in man: Relationship to hypoxanthine-guanine phosphoribosyltransferase
1967
Uric acid lithiasis associated with altered kinetics of hypoxanthine-guanine phosphoribosyltranferase
1976
Intracellular differentiation of purine ribonucleotides derived from endogenous and exogenous sources
1962
Rate-limiting steps in the interconversion of purine ribonucleotides in Ehrlich ascites tumor cells in vitro.
1971
Effects of altered ribonucleotide concentrations on ribonucleotide reduction in intact Chinese hamster ovary cells
1981
Biochemistry of Tumors
2015
Specificity of inhibitors of poly(ADP-ribose) synthesis. Effects on nucleotide metabolism in cultured cells.
1985
Kinetic Studies of Hypoxanthine-Guanine Phosphoribosyltransferase
1968
A kinetic analysis of purine nucleotide synthesis and interconversion in intact Ehrlich ascites tumor cells
1973
The metabolism of formycin, an adenosine analogue
1969
Synthesis of 5-Phosphoribosyl 1-Pyrophosphate from Ribonucleosides in Ehrlich Ascites Tumor Cells in Vitro
1965
Determination of deoxyribonucleoside triphosphates using DNA polymerase: a critical evaluation
1981