Standout Papers
Citation Impact
Citing Papers
Global Cancer in Women: Burden and Trends
2017
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
2021 StandoutNobel
Limits of long-term selection against Neandertal introgression
2019 StandoutNobel
International Variation in Lung Cancer Mortality Rates and Trends among Women
2014
Model‐based detection and analysis of introgressed Neanderthal ancestry in modern humans
2018
Relation of Smoking With Total Mortality and Cardiovascular Events Among Patients With Diabetes Mellitus
2015
Colorectal cancer statistics, 2020
2020 Standout
Cancer statistics, 2023
2023 Standout
The UK Biobank resource with deep phenotyping and genomic data
2018 StandoutNature
National guidelines for smoking cessation in primary care: a literature review and evidence analysis
2017
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
2010 Standout
Cancer statistics, 2020
2020 Standout
Cancer statistics, 2024
2024 Standout
Cancer statistics, 2019
2019 Standout
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2018 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
The cervical cancer epidemic that screening has prevented in the UK
2004
Benefits and limitations of genome-wide association studies
2019
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Genetic effects on gene expression across human tissues
2017 StandoutNature
Infections and cancer: Established associations and new hypotheses
2008
The effect of lanthanum on nerve terminals in goldfish muscle after paralysis with tetanus toxin
1988
Socioeconomic status and the risk of cervical intraepithelial neoplasia grade 3 among oncogenic human papillomavirus DNA‐positive women with equivocal or mildly abnormal cytology
2005
The Acute Risks of Exercise in Apparently Healthy Adults and Relevance for Prevention of Cardiovascular Events
2016
Foundation models for generalist medical artificial intelligence
2023 StandoutNature
Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank
2019
Multi-omics approaches to disease
2017
Patterns and Trends in Human Papillomavirus-Related Diseases in Central and Eastern Europe and Central Asia
2013
A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans
2020 StandoutNobel
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Interaction of tetanus toxin with lipid vesicles. Effects of pH, surface charge, and transmembrane potential on the kinetics of channel formation
1989
The Contribution of Neanderthals to Phenotypic Variation in Modern Humans
2017
The changing landscape of atherosclerosis
2021 StandoutNature
Quantal Neurotransmitter Release and the Clostridial Neurotoxins’ Targets
1995
Flexible and scalable diagnostic filtering of genomic variants using G2P with Ensembl VEP
2019
Pooled cohort study on height and risk of cancer and cancer death
2013
Worldwide trends in cervical cancer incidence: Impact of screening against changes in disease risk factors
2013
Mechanism of action of tetanus and botulinum neurotoxins
1994
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation
2016
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
1993 StandoutNatureNobel
Global cancer statistics
2011 Standout
Is the recent fall in incidence of post-menopausal breast cancer in UK related to changes in use of hormone replacement therapy?
2009
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Cancer statistics for Hispanics/Latinos, 2012
2012
The “All of Us” Research Program
2019 Standout
Human papillomavirus and cervical cancer
2007 Standout
Identification of an ion channel‐forming motif in the primary structure of tetanus and botulinum neurotoxins
1992
Immunity, Inflammation, and Cancer
2010 Standout
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
2018 Standout
Body Mass Index and Breast Cancer Risk According to Postmenopausal Estrogen-Progestin Use and Hormone Receptor Status
2013
21st-Century Hazards of Smoking and Benefits of Cessation in the United States
2013
Structure and function of tetanus and botulinum neurotoxins
1995
Cancer mortality in Europe, 2005–2009, and an overview of trends since 1980
2013
Chapter 1: HPV in the etiology of human cancer
2006
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
2020 StandoutNatureNobel
Genetic predisposition to colorectal cancer
2004
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
2008 Standout
American Cancer Society guidelines on nutrition and physical activity for cancer prevention
2012
Internalization and Proteolytic Action of Botulinum Toxins in CNS Neurons and Astrocytes
1999
Cervical carcinoma and reproductive factors: Collaborative reanalysis of individual data on 16,563 women with cervical carcinoma and 33,542 women without cervical carcinoma from 25 epidemiological studies
2006
Global cancer patterns: causes and prevention
2013
Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies
2009 Standout
Risk of all-cause mortality and cardiovascular disease associated with secondhand smoke exposure: A systematic review and meta-analysis
2015
The Preventable Causes of Death in the United States: Comparative Risk Assessment of Dietary, Lifestyle, and Metabolic Risk Factors
2009 Standout
Field-resolved infrared spectroscopy of biological systems
2020 StandoutNatureNobel
Tetanus toxin produces neuronal loss and a reduction in GABAA but not GABAB binding sites in rat hippocampus
1990
Molecular mechanisms of action of bacterial protein toxins
1994
Blocking effects of tetanus toxin and its fragment [A-B] on the excitatory and inhibitory synapses of the spinal motoneurone of the cat
1989
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
2015 Standout
Action of diphtheria toxin does not depend on the induction of large, stable pores across biological membranes
1990
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Height as an Explanatory Factor for Sex Differences in Human Cancer
2013
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association
2021 Standout
Trends in incidence and mortality rates of squamous cell carcinoma and adenocarcinoma of cervix--worldwide.
2009
Trends in Cervical Squamous Cell Carcinoma Incidence in 13 European Countries: Changing Risk and the Effects of Screening
2005
Interaction of tetanus toxin with lipid vesicles at low pH. Protection of specific polypeptides against proteolysis.
1985
Tetanus toxin receptors on nerve cells contain a trypsin-sensitive component
1986
How many cancer cases and deaths are potentially preventable? Estimates for Australia in 2013
2017
Memory deficits in an experimental hippocampal epileptiform syndrome in rats
1982
Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins
1982 Nature
Tetanus toxin: convulsant action on mouse spinal cord neurons in culture
1983
Tetanus toxin fragment forms channels in lipid vesicles at low pH.
1982
HPV Vaccination and the Risk of Invasive Cervical Cancer
2020
Effect of Body Mass Index on Recurrences in Tamoxifen and Anastrozole Treated Women: An Exploratory Analysis From the ATAC Trial
2010
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Heterologous combinations of heavy and light chains from botulinum neurotoxin A and tetanus toxin inhibit neurotransmitter release in Aplysia
1991
Glass Formation of a Coordination Polymer Crystal for Enhanced Proton Conductivity and Material Flexibility
2016 StandoutNobel
Tetanus toxin is labeled with photoactivatable phospholipids at low pH
1986
Comparative activities of tetanus and botulinum toxins
1984
Partial Defect in the Cholesterol Side-Chain Cleavage Enzyme P450scc (CYP11A1) Resembling Nonclassic Congenital Lipoid Adrenal Hyperplasia
2010
Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease
2020
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Tetanus neurotoxin
1982
Binding of Tetanus Toxin to Somatic Neural Hybrid Cells with Varying Ganglioside Composition
1984
Transmitter release in tetanus and botulinum A toxin-poisoned mammalian motor endplates and its dependence on nerve stimulation and temperature
1983
Human Papillomavirus and Cervical Cancer
2003 Standout
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders
2011 Standout
Clostridial Neurotoxins: Handling and Action at the Cellular and Molecular Level
1986
Prevalence of Subclinical Coronary Artery Disease in Masters Endurance Athletes With a Low Atherosclerotic Risk Profile
2017
Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells
1986 StandoutNatureNobel
Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population
2017 Standout
Intraspinal distribution and reaction in the grey matter with tetanus toxin of intracisternally injected anti-tetanus toxoid F (ab′)2 fragments
1981
Complex ganglioside expression and tetanus toxin binding by PC12 pheochromocytoma cells.
1988
Clinical, Genetic, and Functional Characterization of Four Patients Carrying Partial Loss-of-Function Mutations in the Steroidogenic Acute Regulatory Protein (StAR)
2010
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses
1997 StandoutNobel
A study of the action of tetanus toxin at rat soleus neuromuscular junctions.
1984
Different effects of botulinum A toxin and tetanus toxin on the transmitter releasing process at the mammalian neuromuscular junction
1981
Assembly of SNARE Core Complexes Prior to Neurotransmitter Release Sets the Readily Releasable Pool of Synaptic Vesicles
2000 StandoutNobel
Interaction Between Tetanus Toxin and Rabbit Kidney: A Comparison with Rat Brain Preparations
1986
How do tetanus and botulinum toxins bind to neuronal membranes?
1986
Incidence Trends of Adenocarcinoma of the Cervix in 13 European Countries
2005
Characterization of the channel properties of tetanus toxin in planar lipid bilayers
1988
Colorectal cancer screening: a global overview of existing programmes
2015
Characterization of tetanus toxin binding to rat brain membranes. Evidence for a high-affinity proteinase-sensitive receptor
1986
Fate of tetanus toxin bound to the surface of primary neurons in culture: evidence for rapid internalization.
1985
Global cancer statistics, 2012
2015 Standout
A Study of the Mechanism of Internalisation of Tetanus Toxin by Primary Mouse Spinal Cord Cultures
1987
Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk
2020
Differential effects of various secretagogues on quantal transmitter release from mouse motor nerve terminals treated with botulinum A and tetanus toxin
1987
Selective inhibition of cytokine-induced lysozyme activity by tetanus toxin in the GG2EE macrophage cell line
1989
Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons
1996
Endometrial cancer: Not your grandmother's cancer
2016
Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum a toxin
1980
Tetanus toxin binds with high affinity to neuroblastoma × glioma hybrid cells NG 108-15 and impairs their stimulated acetylcholine release.
1987
Neurotoxins Affecting Neuroexocytosis
2000 Standout
Effect of tetanus toxin on the monosynaptic reflex
1983
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Botulinum A toxin and tetanus toxin do not affect presynaptic membrane currents in mammalian motor nerve endings
1983
Potential Causality and Emerging Medical Therapies for Lipoprotein(a) and Its Associated Oxidized Phospholipids in Calcific Aortic Valve Stenosis
2019
Works of Jane Green being referenced
Nonclassic Lipoid Congenital Adrenal Hyperplasia Masquerading as Familial Glucocorticoid Deficiency
2009
Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk
2011
Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study
2007
Gynecologic Cancer as a “Sentinel Cancer” for Women With Hereditary Nonpolyposis Colorectal Cancer Syndrome
2005
Impact of Gender and Parent of Origin on the Phenotypic Expression of Hereditary Nonpolyposis Colorectal Cancer in a Large Newfoundland Kindred With a Common MSH2 Mutation
2002
Cervical cancer and use of hormonal contraceptives: a systematic review
2003
The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK
2012
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
2015 Standout
Prescribing of hormone therapy for menopause, tibolone, and bisphosphonates in women in the UK between 1991 and 2005
2007
Toward standardizing and reporting colorectal cancer screening indicators on an international level: The international colorectal cancer screening network
2011
Diabetes and modifiable risk factors for cardiovascular disease: the prospective Million Women Study
2008
A Replicated, Genome-Wide Significant Association of Aortic Stenosis With a Genetic Variant for Lipoprotein(a)
2017
Heterogeneity of colorectal cancer risk by tumour characteristics: Large prospective study of UK women
2016
Passive smoking and breast cancer in never smokers: prospective study and meta-analysis
2008
How does tetanus toxin act?
1981
Cervical cancer and hormonal contraceptives: collaborative reanalysis of individual data for 16 573 women with cervical cancer and 35 509 women without cervical cancer from 24 epidemiological studies
2007
Adiposity and ischemic and hemorrhagic stroke
2016
Is there retrograde axonal transport of tetanus toxin in both α and γ fibres?
1977 Nature
Coronary heart disease incidence in women by waist circumference within categories of body mass index
2013
Frequent Physical Activity May Not Reduce Vascular Disease Risk as Much as Moderate Activity
2015