Standout Papers
Citation Impact
Citing Papers
Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors
2008
DiffVar: a new method for detecting differential variability with application to methylation in cancer and aging
2014
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice
2003
An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
2014 Science
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Characterization of Melanoma Cells Capable of Propagating Tumors from a Single Cell
2010
Identification of Tumor-Initiating Cells in a p53-Null Mouse Model of Breast Cancer
2008
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
2014 Standout
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
Multipotent CD15+ Cancer Stem Cells in Patched-1 –Deficient Mouse Medulloblastoma
2009
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
1996
ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
2008
Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011
2011 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Purification and Ex Vivo Expansion of Fully Functional Salivary Gland Stem Cells
2014
Triple-Negative Breast Cancer
2010 Standout
Guide: a desktop application for analysing gene expression data
2013
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
2015 Nature
Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone
2011
Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate
2011
Making a tumour's bed: glioblastoma stem cells and the vascular niche
2007
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
1990
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors Following Chemotherapy
2008
Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
2011
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
1999
Hammerhead-mediated processing of satellite pDo500 family transcripts from Dolichopoda cave crickets
2000
Integrins in cancer: biological implications and therapeutic opportunities
2009 Standout
De novo detection of differentially bound regions for ChIP-seq data using peaks and windows: controlling error rates correctly
2014
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
2012 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Detection of Simultaneous Group Effects in MicroRNA Expression and Related Target Gene Sets
2012
Optimizing the noise versus bias trade-off for Illumina whole genome expression BeadChips
2010
Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity
2013
Tumorigenic Cells Are Common in Mouse MPNSTs but Their Frequency Depends upon Tumor Genotype and Assay Conditions
2012
Crystal structure of the heterodimeric bZIP transcription factor c-Fos–c-Jun bound to DNA
1995 Nature
To differentiate or not — routes towards metastasis
2012
Interactions between cancer stem cells and their niche govern metastatic colonization
2011 Nature
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
2010
Unravelling the complexity of metastasis — molecular understanding and targeted therapies
2011
In vitro evolution suggests multiple origins for the hammerhead ribozyme
2001 StandoutNatureNobel
Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer
2007 Standout
GSVA: gene set variation analysis for microarray and RNA-Seq data
2013 Standout
Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland Organogenesis
2013
Cancer stem cells in solid tumors
2007
Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
2010
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
Evolution, development, and plasticity of the human brain: from molecules to bones
2013
Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia
2007
Identification of molecular determinants of primary and metastatic tumour re-initiation in breast cancer
2015
TGFβ: the molecular Jekyll and Hyde of cancer
2006
Recent advances in cancer stem cells
2008
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
2010 Standout
Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures
2008
Forcing cells to change lineages
2009 Nature
Evolution of the neocortex: a perspective from developmental biology
2009
Estimating the proportion of microarray probes expressed in an RNA sample
2010
In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties
2008
Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
2012
Tumor metastasis: moving new biological insights into the clinic
2013
Dclk1 distinguishes between tumor and normal stem cells in the intestine
2012
Leukocytes in Mammary Development and Cancer
2010
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
2010
Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status
2010
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
2011
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
2010 Standout
Mechanisms Governing Metastatic Dormancy and Reactivation
2013
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
2015 Nature
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
A Switch Between Two-, Three-, and Four-stranded Coiled Coils in GCN4 Leucine Zipper Mutants
1993 Science
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
2010 Nature
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
2010 Nature
Parallel progression of primary tumours and metastases
2009
Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
2015
Emerging Biological Principles of Metastasis
2017 Standout
Efficient tumour formation by single human melanoma cells
2008 Nature
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
The cancer stem cell: premises, promises and challenges
2011 Standout
DNA Damage-Mediated Induction of a Chemoresistant Niche
2010
Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB
1990
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
2010
Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia
2014
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
1990
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Cancer stem cells: mirage or reality?
2009
CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis
2009
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
From RNA-seq reads to differential expression results
2010
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
Cell of origin determines clinically relevant subtypes of MLL-rearranged AML
2012
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer
2010
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Crypt stem cells as the cells-of-origin of intestinal cancer
2008 StandoutNature
Genetic variegation of clonal architecture and propagating cells in leukaemia
2010 Nature
Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells
2010
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration
2011
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Human-Specific Transcriptional Networks in the Brain
2012
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Modeling Development and Disease with Organoids
2016 Standout
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition
2009
Deconstructing the molecular portraits of breast cancer
2010
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Epithelial to Mesenchymal Transition Is Mechanistically Linked with Stem Cell Signatures in Prostate Cancer Cells
2010
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
2013
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites
1987
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Aire
2009
Comparative sequence and structure of circular RNAs from two isolates of lucerne transient streak virus
1983
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
2011
Phenotypic characterization of human colorectal cancer stem cells
2007 Standout
Viroids
1983
Viroids and prions.
1982
Sorting mouse jejunal epithelial cells with CD24 yields a population with characteristics of intestinal stem cells
2010
Viroid processing: a model involving the central conserved region and hairpin I.
1986
Viroid RNAs of cadang-cadang disease of coconuts
1982 Nature
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid
1986
Developmental stage‐specific contribution of LGR5 + cells to basal and luminal epithelial lineages in the postnatal mammary gland
2012
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Micrometastatic Disease and Metastatic Outgrowth: Clinical Issues and Experimental Approaches
2009
Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP
1994 StandoutScienceNobel
Structure, sequence and expression of the hepatitis delta (δ) viral genome
1986 StandoutNatureNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Hop stunt viroid: molecular cloning and nucleotide sequence of the complete cDNA copy
1983
What is an adult stem cell?
2015 Science
The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
2012
The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote
2013 Standout
Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture
1993
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
Structure and function of viroids
1983
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Identification of a Protein That Purifies with the Scrapie Prion
1982 StandoutScienceNobel
Human hepatitis delta virus RNA subfragments contain an autocleavage activity.
1989
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
An epigenetically distinct breast cancer cell subpopulation promotes collective invasion
2015
Camera: a competitive gene set test accounting for inter-gene correlation
2012
Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution
2009
TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.
1991
Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants
1987 StandoutNobel
Specific Interactions in RNA Enzyme-Substrate Complexes
1989 StandoutScienceNobel
Chicken vitellogenin gene-binding protein, a leucine zipper transcription factor that binds to an important control element in the chicken vitellogenin II promoter, is related to rat DBP.
1991
Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.
1994
Stem cell concepts renew cancer research
2008
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
2010
Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells
1989 StandoutScienceNobel
Hematopoietic commitment during embryonic stem cell differentiation in culture.
1993
CD133 Expression Defines a Tumor Initiating Cell Population in Primary Human Ovarian Cancer
2009 Standout
Comparative sequence and structure of viroid-like RNAs of two plant viruses
1982
Molecular cloning of potato spindle tuber viroid (PSTV) cDNA synthesized by enzymatic elongation of PSTV-specific DNA primers: A general strategy for viroid cloning
1985
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Circulating Tumor Cells and Bone Marrow Micrometastasis
2008
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
2013 Standout
Activation of fibroblasts in cancer stroma
2010
Quantification of regenerative potential in primary human mammary epithelial cells
2015
Antigenomic RNA of human hepatitis delta virus can undergo self-cleavage
1988
Works of Jane E. Visvader being referenced
Early Asymmetry of Gene Transcription in Embryonic Human Left and Right Cerebral Cortex
2005 Science
The Mammary Progenitor Marker CD61/β3 Integrin Identifies Cancer Stem Cells in Mouse Models of Mammary Tumorigenesis
2008
Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL.
1991
Resident macrophages influence stem cell activity in the mammary gland
2009
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
2010
Steroid Hormone Receptor Status of Mouse Mammary Stem Cells
2006
Citrus exocortis viroid: nucleotide sequence and secondary structure of an Australian isolate
1982
In situ identification of bipotent stem cells in the mammary gland
2014 Nature
Control of mammary stem cell function by steroid hormone signalling
2010 Nature
Global Changes in the Mammary Epigenome Are Induced by Hormonal Cues and Coordinated by Ezh2
2013
Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment
2008
FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation
1997
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
The Ets transcription factor Elf5 specifies mammary alveolar cell fate
2008
Mammary stem cells and the differentiation hierarchy: current status and perspectives
2014
Combined immune checkpoint blockade as a therapeutic strategy for BRCA1 -mutated breast cancer
2017
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
2009
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
2006
Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer
2013
Cells of origin in cancer
2011 Nature
Remodeling of the Lymphatic Vasculature during Mouse Mammary Gland Morphogenesis Is Mediated via Epithelial-Derived Lymphangiogenic Stimuli
2012
Generation of a functional mammary gland from a single stem cell
2006 StandoutNature
Cancer Stem Cells: Current Status and Evolving Complexities
2012
Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
2009
Comparison of multimeric plus and minus forms of viroids and virusoids
1985
The LIM Domain Protein LMO4 Interacts with the Cofactor CtIP and the Tumor Suppressor BRCA1 and Inhibits BRCA1 Activity
2002
ROAST: rotation gene set tests for complex microarray experiments
2010
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line.
1992
Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element.
1988
Helix-loop-helix genes translocated in lymphoid leukemia
1991
Trans-dominant negative mutants of Fos and Jun.
1990
Mammary Stem Cells and Mammopoiesis
2006
Defective Neural Tube Closure and Anteroposterior Patterning in Mice Lacking the LIM Protein LMO4 or Its Interacting Partner Deaf-1
2004
Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14
2011
Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins.
1989
Eleven new sequence variants of citrus exocortis viroid and the correlation of sequence with pathogenicity
1985
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
2006 Standout
Derivation of a robust mouse mammary organoid system for studying tissue dynamics
2016
Infectivity andin vitromutagenesis of monomeric cDNA clones of citrus exocortis viroid indicates the site of processing of viroid precursors
1985