Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Evolutionary changes in promoter and enhancer activity during human corticogenesis
2015 Science
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Merkel Cells Are Essential for Light-Touch Responses
2009 Science
Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis
2009
Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system
1998
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
1998
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
1996
Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system.
1992
Voltage-activated ion channels and Ca2+-induced Ca2+ release shape Ca2+ signaling in Merkel cells
2008
Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein
1995 Science
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.
1995
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
1999 StandoutNature
A transcription factor controlling development of peripheral sense organs in C. elegans
1995 Nature
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Lethal of Scute requires overexpression of Daughterless to elicit ectopic neuronal development during embryogenesis in Drosophila
1997
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis
2012
Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence
1996
Old and new functions of proneural factors revealed by the genome-wide characterization of their transcriptional targets
2011
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Mammalian Merkel cells are descended from the epidermal lineage
2009
Essential role of Mash-2 in extraembryonic development
1994 Nature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
1990
Developmental diversification of cortical inhibitory interneurons
2018 Nature
NEUROGENIN1 and NEUROGENIN2 control two distinct waves of neurogenesis in developing dorsal root ganglia
1999
Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex
2007
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
2010
Piezo2 is required for Merkel-cell mechanotransduction
2014 StandoutNatureNobel
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
1998 StandoutNobel
The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
1990 Standout
Accelerated Evolution of Nervous System Genes in the Origin of Homo sapiens
2004
Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system
1993
Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development
1996
Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
2009
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
2014
Structure and Promoter Analysis of the Gene Encoding the Mouse Helix-Loop-Helix Factor HES-5
1995
Complete nucleotide sequence of the rabbit β-like globin gene cluster
1989
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice
1997
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
1989
Direct lineage conversions: unnatural but useful?
2011
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
The bHLH Protein NEUROGENIN 2 Is a Determination Factor for Epibranchial Placode–Derived Sensory Neurons
1998
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Cellular and molecular control of neurogenesis in the mammalian telencephalon
2005
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
neurogenin1 Is Essential for the Determination of Neuronal Precursors for Proximal Cranial Sensory Ganglia
1998
Swelling-Activated Ca2+ Channels Trigger Ca2+ Signals in Merkel Cells
2008
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
1989 StandoutNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
2015
Glial cells generate neurons: the role of the transcription factor Pax6
2002
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents
2017 Nature
Friedrich Sigmund Merkel and his “Merkel cell”, morphology, development, and physiology: Review and new results
2003
Homeobox genes and axial patterning
1992 Standout
Neurogenesis and the Cell Cycle
2003
Proneural genes and the specification of neural cell types
2002 Standout
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
1994 Standout
Molecular tuning of electroreception in sharks and skates
2018 StandoutNatureNobel
Basic local alignment search tool
1990 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors
2007 Nature
Identification of neurogenin, a Vertebrate Neuronal Determination Gene
1996
Luminescent and Redox-Active Polynuclear Transition Metal Complexes
1996 Standout
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation
2018
Implantation and the placenta: key pieces of the development puzzle
1994 StandoutScience
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Genetic and epigenetic control in neural crest development
1994
The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development
1991
Protocols for two- and three-color fluorescent RNA in situ hybridization of the main and accessory olfactory epithelia in mouse
2004
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
2011 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
2017
A Single Rostrocaudal Colonization of the Rodent Intestine by Enteric Neuron Precursors Is Revealed by the Expression of Phox2b, Ret, and p75 and by Explants Grown under the Kidney Capsule or in Organ Culture
1998
Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development
1997
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Lineage-specific regulators couple cell lineage asymmetry to the transcription of the Caenorhabditis elegans POU gene unc-86 during neurogenesis.
1996 StandoutNobel
Computation identifies structural features that govern neuronal firing properties in slowly adapting touch receptors
2014
Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees
2005 StandoutScienceNobel
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Molecular profiling reveals synaptic release machinery in Merkel cells
2004
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Expression of the c-ret proto-oncogene during mouse embryogenesis
1993
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis
2000 Standout
Analysis of the Globose Basal Cell Compartment in Rat Olfactory Epithelium Using GBC-1, a New Monoclonal Antibody against Globose Basal Cells
1996
A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.
1989
The Expression Pattern of the Transcription Factor Phox2 Delineates Synaptic Pathways of the Autonomic Nervous System
1996
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Dendrimers of Nanometer Size Based on Metal Complexes: Luminescent and Redox‐Active Polynuclear Metal Complexes Containing up to Twenty‐Two Metal Centers
1995
TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor
1992
Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic mouse heart
1992
Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
2000
Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis.
1997
The Neuron-Restrictive Silencer Factor (NRSF): A Coordinate Repressor of Multiple Neuron-Specific Genes
1995 Science
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.
1992
Selective elimination of mRNAs in vivo: complementary oligodeoxynucleotides promote RNA degradation by an RNase H-like activity.
1987 StandoutNobel
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.
1989
The Regularity of Sustained Firing Reveals Two Populations of Slowly Adapting Touch Receptors in Mouse Hairy Skin
2010
XASH genes promote neurogenesis in Xenopus embryos
1994
In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR
1989 Science
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Body-Wall Muscle Formation in Caenorhabditis elegans Embryos that Lack the MyoD Homolog hlh-1
1992 StandoutScienceNobel
Conservation of the Notch signalling pathway in mammalian neurogenesis
1997 StandoutNobel
RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
2002
Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis
2008
Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.
1991
Evidence for Developmentally Programmed Transdifferentiation in Mouse Esophageal Muscle
1995 StandoutScienceNobel
Notch1 is required for the coordinate segmentation of somites
1995
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy
2017
MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity
1998
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.
1996
Diversity and Pattern in the Developing Spinal Cord
1996 Science
Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts
1996
Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
1993
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor.
1995
Works of Jane E. Johnson being referenced
Synthesis and characterization of bipyridylruthenium(II) complexes bound to the bridging ligand dipyrido(2,3-a; 2′,3′-h)phenazine (dpop)
1993
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.
1991
DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer.
1992
A Role for the Helix-Loop-Helix Protein Id2 in the Control of Oligodendrocyte Development
2001
Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord
2006
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
1993
Math1-driven GFP expression in the developing nervous system of transgenic mice
2003
Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors
1990 Nature
Correct Coordination of Neuronal Differentiation Events in Ventral Forebrain Requires the bHLH Factor MASH1
1999
XATH-1,a Vertebrate Homolog ofDrosophila atonal,Induces Neuronal Differentiation within Ectodermal Progenitors
1997
Mash1 specifies neurons and oligodendrocytes in the postnatal brain
2004
Isolation of neural stem cells from the postnatal cerebellum
2005
Expression of a transfected mouse muscle-creatine kinase gene is induced upon growth factor deprivation of myogenic but not of nonmyogenic cells
1989
Autoregulation of Neurogenesis by GDF11
2003
The Comparative Pathology of Genetically Engineered Mouse Models for Neuroendocrine Carcinomas of the Lung
2015
A nonclassical bHLH–Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling
2008
In Vivo Neuronal Subtype-Specific Targets of Atoh1 (Math1) in Dorsal Spinal Cord
2011
Wnt signalling required for expansion of neural crest and CNS progenitors
1997 Nature
Crossinhibitory Activities of Ngn1 and Math1 Allow Specification of Distinct Dorsal Interneurons
2001
Genetic Fate Mapping Reveals That the Caudal Ganglionic Eminence Produces a Large and Diverse Population of Superficial Cortical Interneurons
2010
Transcription unit of the rabbit beta 1 globin gene.
1985
Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn
2005
The Muscle Creatine Kinase Gene Is Regulated by Multiple Upstream Elements, Including a Muscle-Specific Enhancer
1988
Autoregulation and multiple enhancers control Math1 expression in the developing nervous system
2000
Muscle creatine kinase sequence elements regulating skeletal and cardiac muscle expression in transgenic mice.
1989
Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification
2004
Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neuronal differentiation of P19 embryonal carcinoma cells
1992
Transcriptional Regulation of the Muscle Creatine Kinase Gene and Regulated Expression in Transfected Mouse Myoblasts
1986
Muscle Creatine Kinase Sequence Elements Regulating Skeletal and Cardiac Muscle Expression in Transgenic Mice
1989
Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.
1986
Modulation of the notch signaling byMash1andDlx1/2regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon
2002
The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.
1988