Citation Impact
Citing Papers
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
2003 Standout
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer
2009 Standout
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
BRAF alterations are associated with complex mutational profiles in malignant melanoma
2004
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies
1999
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
1998
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
The management of advanced thyroid cancer
2004
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis
2005 StandoutNobel
Targeted Next-Generation Sequencing Panel (ThyroSeq) for Detection of Mutations in Thyroid Cancer
2013
Familial non-medullary thyroid carcinoma displays the features of clinical anticipation suggestive of a distinct biological entity
2008
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
1997 Standout
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Applicability of Intraoperative Parathyroid Hormone Assay During Thyroidectomy
2002
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
The pressure rises: update on the genetics of phaeochromocytoma
2002
A multicenter cohort study of total thyroidectomy and routine central lymph node dissection for cN0 papillary thyroid cancer
2011
The Thyroid Nodule
2004 Standout
Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C
2000
Inherited Mutations in PTEN That Are Associated with Breast Cancer, Cowden Disease, and Juvenile Polyposis
1997
Influence of prophylactic central lymph node dissection on postoperative thyroglobulin levels and radioiodine treatment in papillary thyroid cancer
2010
Head and neck cancer
2008 Standout
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
An Updated Systematic Review and Commentary Examining the Effectiveness of Radioactive Iodine Remnant Ablation in Well-Differentiated Thyroid Cancer
2008
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Oncogenic role of miR‐17‐92 cluster in anaplastic thyroid cancer cells
2008
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Current State and Future Perspective of Molecular Diagnosis of Fine-Needle Aspiration Biopsy of Thyroid Nodules
2011
Medullary Thyroid Carcinoma
2007
The Hallmarks of Cancer
2000 Standout
BRAF Mutation in Papillary Thyroid Cancer and Its Value in Tailoring Initial Treatment
2012
A novel classification system for patients with PTC: addition of the new variables of large (3 cm or greater) nodal metastases and reclassification during the follow-up period
2004
PTEN: One Gene, Many Syndromes
2003
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
2011
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein
1999 StandoutNobel
BRAF V600E Mutation Independently Predicts Central Compartment Lymph Node Metastasis in Patients with Papillary Thyroid Cancer
2012
Influence of age and primary tumor size on the risk for residual/recurrent well‐differentiated thyroid carcinoma
2009
Beyond the Suspicious Thyroid Fine Needle Aspirate
2003
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Differentiated thyroid carcinomas with vascular invasion: a comparative study of follicular, Hürthle cell and papillary thyroid carcinoma
2002
Systematic review and meta‐analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy alone
2009
Identification of PTEN mutations in metastatic melanoma specimens
2000
BRAF mutations in papillary carcinomas of the thyroid
2003
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Epigenetic PTEN Silencing in Malignant Melanomas without PTEN Mutation
2000
Staging systems for follicular thyroid carcinoma: application to 171 consecutive patients treated in a tertiary referral centre
2007
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns
2010
Survival and Death Causes in Differentiated Thyroid Carcinoma
2006
Validation of the QTNM staging system for cancer-specific survival in patients with differentiated thyroid cancer
2013
Sonographically‐Directed Neck Dissection for Recurrent Thyroid Carcinoma
2008
Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer
2015 Standout
Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
2012 Standout
Hereditary Colorectal Cancer
2003 Standout
Breast-Cancer Stromal Cells with TP53 Mutations and Nodal Metastases
2007
Mutations of the human PTEN gene
2000
Central Compartment Reoperation for Recurrent/Persistent Differentiated Thyroid Cancer: Patterns of Recurrence, Morbidity, and Prediction of Postoperative Hypocalcemia
2010
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Cloning and characterization of a novel human gene related to vascular endothelial growth factor.
1996
Total Thyroidectomy Plus Neck Dissection in Differentiated Papillary Thyroid Carcinoma Patients
2007 Standout
Thyroid pathologic findings in patients with Cowden disease
1999
Routine ipsilateral level VI lymphadenectomy reduces postoperative thyroglobulin levels in papillary thyroid cancer
2006
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
Protein Tyrosine Phosphatases in the Human Genome
2004 Standout
RET/PTC Rearrangement in Thyroid Tumors
2002
Central cervical lymph node metastases in papillary thyroid cancer: a systematic review of imaging‐guided and prophylactic removal of the central compartment
2011
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract
1999
Somatic mutations of thePTEN tumor suppressor gene in sporadic follicular thyroid tumors
1998
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
Molecular genetics and diagnosis of thyroid cancer
2011
Lymph Node Ratio of the Central Compartment is a Significant Predictor for Locoregional Recurrence After Prophylactic Central Neck Dissection in Patients with Thyroid Papillary Carcinoma
2013
Staging Systems for Papillary Thyroid Carcinoma
2007
Long-term outcomes of injection laryngoplasty in patients with potentially recoverable vocal fold paralysis1
2010
Hamartomatous Polyposis Syndromes: Molecular Genetics, Neoplastic Risk, and Surveillance Recommendations
2001
Sirolimus for Kaposi's Sarcoma in Renal-Transplant Recipients
2005 Standout
Thyroid pathology in four patients with Cowden’s disease
2003
Tumours of familial origin in the head and neck
2006
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
2001 StandoutNobel
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
The RASSF proteins in cancer; from epigenetic silencing to functional characterization
2009
Controversies in the Surgical Management of Newly Diagnosed and Recurrent/Residual Thyroid Cancer
2009
Pattern of Spread to the Lateral Neck in Metastatic Well-Differentiated Thyroid Cancer: A Systematic Review and Meta-Analysis
2012
The Benefits and Risks of I-131 Therapy in Patients with Well-Differentiated Thyroid Cancer
2009
Considerations for Personalized Surgery in Patients with Papillary Thyroid Cancer
2010
Lessons from Mouse Models of Thyroid Cancer
2009
Poorly Differentiated Follicular Thyroid Carcinoma: Prognostic Factors and Relevance of Histological Classification
2007
In Papillary Thyroid Cancer, Preoperative Central Neck Ultrasound Detects Only Macroscopic Surgical Disease, But Negative Findings Predict Excellent Long-Term Regional Control and Survival
2012
BRAF : A Tool in the Decision to Perform Elective Neck Dissection?
2012
Molecular Alterations in Partially-Encapsulated or Well-Circumscribed Follicular Variant of Papillary Thyroid Carcinoma
2013
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
1999 Standout
Management of Simple Nodular Goiter: Current Status and Future Perspectives
2003
Complications of Neck Dissection for Thyroid Cancer
2002
Hyperplasia of Lymphatic Vessels in VEGF-C Transgenic Mice
1997 StandoutScience
TERTPromoter Mutations and Their Association withBRAFV600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer
2014
Surgery of Well-Differentiated Thyroid Carcinoma: The Pendulum Swings Back in the Central Neck
2010
Central Lymph Node Dissection in Differentiated Thyroid Cancer
2007
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.
1999
BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence
2014
Role of prophylactic central neck dissection in cN0 papillary thyroid cancer.
2009
Genomic Dissection of Hurthle Cell Carcinoma Reveals a Unique Class of Thyroid Malignancy
2013
AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation
1999
RAS Mutations Are the Predominant Molecular Alteration in Poorly Differentiated Thyroid Carcinomas and Bear Prognostic Impact
2009
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Prophylactic Central Neck Dissection and Local Recurrence in Papillary Thyroid Cancer: A Meta-analysis
2010
The role of microRNA genes in papillary thyroid carcinoma
2005 Standout
The Biology and Clinical Relevance of the PTEN Tumor Suppressor Pathway
2004
Critical Roles of Pten in B Cell Homeostasis and Immunoglobulin Class Switch Recombination
2003 StandoutNobel
Preablation 131-I Scans With SPECT/CT in Postoperative Thyroid Cancer Patients: What Is the Impact on Staging?
2013
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis
1996
Germline PTEN mutations in Cowden syndrome-like families.
1998
Hamartomatous Polyposis Syndromes: Molecular Genetics, Neoplastic Risk, and Surveillance Recommendations
2001
Survival and Therapeutic Modalities in Patients with Bone Metastases of Differentiated Thyroid Carcinomas
2001
Evaluation of Postoperative Radioactive Iodine Scans in Patients who Underwent Prophylactic Central Lymph Node Dissection
2012
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Simplifying the TNM System for Clinical Use in Differentiated Thyroid Cancer
2009
Allelic imbalance and mutations of thePTEN gene in ovarian cancer
2000
Prophylactic central neck dissection for papillary thyroid cancer
2012
Papillary Thyroid Carcinoma Associated with Papillary Renal Neoplasia: Genetic Linkage Analysis of a Distinct Heritable Tumor Syndrome*
2000
Lateral cervical lymph node metastases in papillary thyroid cancer: a systematic review of imaging‐guided and prophylactic removal of the lateral compartment
2012
Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary.
2000
PTEN mutations and microsatellite instability in complex atypical hyperplasia, a precursor lesion to uterine endometrioid carcinoma.
1998
Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas.
1995
Guidelines for the management of thyroid cancer
2014 Standout
Lateral and Mediastinal Lymph Node Dissection in Differentiated Thyroid Carcinoma: Indications, Benefits, and Risks
2007
PTEN Gene Alterations in Lymphoid Neoplasms
1998
Genetics of Cowden syndrome: through the looking glass of oncology.
1998
Papillary thyroid carcinoma nodal surgery directed by a preoperative radiographic map utilizing CT scan and ultrasound in all primary and reoperative patients
2013
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p.
2000
Angiogenesis in Endocrine Tumors
2003
Dissecting the roles of TRBP and PACT in double‐stranded RNA recognition and processing of noncoding RNAs
2015
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Overexpression and overactivation of Akt in thyroid carcinoma.
2001
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
The Pten/PI3K pathway governs the homeostasis of Vα14iNKT cells
2006 StandoutNobel
A human homolog of the Schizosaccharomyces pombe rad9 + checkpoint control gene
1996
Extent of Routine Central Lymph Node Dissection With Small Papillary Thyroid Carcinoma
2007
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.
2000 StandoutNobel
Works of Jan Zedenius being referenced
Genotype‐phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium
1995
The Ras EffectorNORE1AIs Suppressed in Follicular Thyroid Carcinomas with aPAX8-PPARγ Fusion
2006
Silencing of the PTEN tumor‐suppressor gene in anaplastic thyroid cancer
2002
Incidence and survival of Swedish patients with differentiated thyroid cancer
2003
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
2013
Involvement of the PAX8/Peroxisome Proliferator-Activated Receptor γ Rearrangement in Follicular Thyroid Tumors
2003
MULTINODULAR GOITRE PRESENTING AS A CLINICAL SINGLE NODULE: HOW EFFECTIVE IS HEMITHYROIDECTOMY?
1999
Clinically significant prognostic factors for differentiated thyroid carcinoma
2005
ROUTINE AUTOTRANSPLANTATION OF AT LEAST ONE PARATHYROID GLAND DURING TOTAL THYROIDECTOMY MAY REDUCE PERMANENT HYPOPARATHYROIDISM TO ZERO
1999
The phospholipase C β3 gene located in the MEN1 region shows loss of expression in endocrine tumours
1994
Thymic Carcinoids in Multiple Endocrine Neoplasia Type 1
1998
RET/PTCandRETTyrosine Kinase Expression in Adult Papillary Thyroid Carcinomas1
1998
Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors
1996
Loss of heterozygosity in sporadic parathyroid tumours: involvement of chromosome 1 and the MEN1 gene locus in 11q13.
2000
Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma
2013
Diagnosis and Prognosis of Iatrogenic Injury of the Recurrent Laryngeal Nerve
2009
Predictors of outcome in patients with papillary thyroid carcinoma
2006
A PCR-based expression signature of malignancy in follicular thyroid tumors
2007
Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas.
1995
Expression of the RET proto-oncogene in papillary thyroid carcinoma and its correlation with clinical outcome
2001
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.
1997
Molecular Genetics of Thyroid Tumors and Surgical Decision‐making
2000
Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas.
1997
Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas
1995
Influence of surgical and postoperative treatment on survival in differentiated thyroid cancer
2007
Anaplastic Giant Cell Carcinoma of the Thyroid Gland: Treatment and Survival Over a 25‐Year Period
1998
Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization
1999