Citation Impact
Citing Papers
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA
2004 Science
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
The Somatomedin Hypothesis: 2001
2001
Myofibroblasts and mechano-regulation of connective tissue remodelling
2002 Standout
Genetics of mouse growth
1998
Hallmarks of Cancer: The Next Generation
2011 Standout
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock
2006
The DNA-damage response in human biology and disease
2009 StandoutNature
Minireview: Tissue-SpecificVersusGeneralized Gene Targeting of theigf1andigf1rGenes and Their Roles in Insulin-Like Growth Factor Physiology
2001
Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
2012
Atopic Dermatitis
2008 Standout
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
Signal transduction via platelet-derived growth factor receptors
1998
Endocrine regulation of heat shock protein mRNA levels in long-lived dwarf mice
2009
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
Mutant mice with small amounts of BubR1 display accelerated age-related gliosis
2006
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
2006
Pdgfr-αmediates testis cord organization and fetal Leydig cell development in the XY gonad
2003
PDGF signaling in cells and mice
2004
Neuron-Specific Ablation of PDGF-B Is Compatible with Normal Central Nervous System Development and Astroglial Response to Injury
2003
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development
2006
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Myofibroblasts: Molecular crossdressers
2001
PDGFB Regulates the Development of the Labyrinthine Layer of the Mouse Fetal Placenta
1999
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Insight into the physiological functions of PDGF through genetic studies in mice
2004
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Platelet-derived growth factor is constitutively secreted from neuronal cell bodies but not from axons
2000
Mitochondrial diseases
2012
Cardiac hypertrophy and failure: lessons learned from genetically engineered mice
2001
Tipping the metabolic scales towards increased longevity in mammals
2015
Genetic Association Between an AACC Insertion in the 3′UTR of the Stratum Corneum Chymotryptic Enzyme Gene and Atopic Dermatitis
2004
Axis of ageing: telomeres, p53 and mitochondria
2012
NF-κB inhibition delays DNA damage–induced senescence and aging in mice
2012
Random Point Mutations with Major Effects on Protein-Coding Genes Are the Driving Force behind Premature Aging in mtDNA Mutator Mice
2009
DNA Repair, Genome Stability, and Aging
2005
Mitochondrial longevity pathways
2010
MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis
2008
Mitochondria: In Sickness and in Health
2012 Standout
Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome
2003 Standout
Distribution and Functions of Platelet-Derived Growth Factors and Their Receptors during Embryogenesis
1997
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Regulation of PDGF and its receptors in fibrotic diseases
2004
Mitochondria, Oxidants, and Aging
2005 Standout
Regulated overexpression of interleukin 11 in the lung. Use to dissociate development-dependent and -independent phenotypes.
1997
Paraoxonase, a cardioprotective enzyme: continuing issues
2004
Overexpression of PDGF-A in the Lung Epithelium of Transgenic Mice Produces a Lethal Phenotype Associated with Hyperplasia of Mesenchymal Cells
2001
Mitochondrial fragmentation in neurodegeneration
2008
Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins
2011
Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
2009
An Allelic Series at the PDGFαR Locus Indicates Unequal Contributions of Distinct Signaling Pathways During Development
2002
Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice
2010
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
2006
Not all myofibroblasts are alike
1998
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
The Immunopathogenesis of Sepsis in Elderly Patients
2005
Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro
2000
Structural and functional specificities of PDGF‐C and PDGF‐D, the novel members of the platelet‐derived growth factors family
2005
Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging
2011
Understanding the Odd Science of Aging
2005 Standout
Stems Cells and the Pathways to Aging and Cancer
2008
PDGF‐a/PDGF alpha‐receptor signaling is required for lung growth and the formation of alveoli but not for early lung branching morphogenesis
2001
Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
2010
Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA
2008
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Control of progenitor cell number by mitogen supply and demand
2001
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Platelet‐derived growth factor signaling as a cue of the epithelial–mesenchymal interaction required for anuran skin metamorphosis
2003
Role of the Ubiquitin Conjugation System in the Maintenance of Mitochondrial Homeostasis
2008
Mechanisms of Myofibroblast Activity and Phenotypic Modulation
1999
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Animal Models of Atopic Dermatitis
2008
PDGF and cardiovascular disease
2004
PDGF-D, a new protease-activated growth factor
2001
Minimizing the damage: repair pathways keep mitochondrial DNA intact
2012
Transcription of the platelet-derived growth factor A-chain gene
2003
New perspectives on epidermal barrier dysfunction in atopic dermatitis: Gene–environment interactions
2006
Expression analysis of PDGF-C in adult and developing mouse tissues
2002
PDGF-C is a new protease-activated ligand for the PDGF α-receptor
2000
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
2008
Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice
2005
The Hallmarks of Aging
2013 Standout
Atherosclerosis
2000 StandoutNature
Specific Inhibitors of Platelet-Derived Growth Factor or Epidermal Growth Factor Receptor Tyrosine Kinase Reduce Pulmonary Fibrosis in Rats
1999
The Aging Stress Response
2010
Mitochondrial DNA Polymerase W748S Mutation: A Common Cause of Autosomal Recessive Ataxia with Ancient European Origin
2005
Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
2011
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
2007
Blockade of Platelet-Derived Growth Factor or Its Receptors Transiently Delays but Does Not Prevent Fibrous Cap Formation in ApoE Null Mice
2002
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Nuclear and mitochondrial DNA repair: similar pathways?
2005
Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease
2004 Standout
Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo
1998
Mitochondrial DNA and ageing
2006
Impaired Distal Airway Development in Mice Lacking Elastin
2000
Rapid Activation of PDGF-A and -B Expression at Sites of Lung Injury in Asbestos-exposed Rats
1997
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Platelet-Derived Growth Factor Receptor-α in Ventricular Zone Cells and in Developing Neurons
2001
Proliferation and the Monoclonal Origins of Atherosclerotic Lesions
1998
The Somatomedin Hypothesis: 2001
2001
A specific requirement for PDGF-C in palate formation and PDGFR-α signaling
2004
Inflammaging: disturbed interplay between autophagy and inflammasomes
2012
Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact
1999
Guidance of mesoderm cell migration in theXenopusgastrula requires PDGF signaling
2004
A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine
2005 Standout
Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice
1997 StandoutScience
Partial Deletion of Pten in the Hypothalamus Leads to Growth Defects that Cannot be Rescued by Exogenous Growth Hormone
2008 StandoutNobel
Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus
2000
Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice
2005
Phenotypic consequences of lung-specific inducible expression of FGF-3
2001 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Management of growth hormone deficiency in adults
2007
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Platelet-derived growth factor β receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3′ kinase signaling
1999
Myofibroblasts. I. Paracrine cells important in health and disease
1999
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
2005 StandoutScience
Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction
2009
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus
2001
PDGF α-receptor mediated cellular responses are not dependent on Src family kinases in endothelial cells
1998
Signal transduction by reactive oxygen species
2011 Standout
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease
1997 StandoutNobel
A circadian gene expression atlas in mammals: Implications for biology and medicine
2014 Standout
Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
2012
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
1999
Cilia and Developmental Signaling
2007
The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites
1997
Roles of PDGF in animal development
2003
DNA Repair Defects in Stem Cell Function and Aging
2004
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Leydig Cell Loss and Spermatogenic Arrest in Platelet-Derived Growth Factor (Pdgf)-a–Deficient Mice
2000
Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet
2010
Mouse models of mitochondrial DNA defects and their relevance for human disease
2009
The Fibronectin Domain ED-A Is Crucial for Myofibroblastic Phenotype Induction by Transforming Growth Factor-β1
1998 Standout
Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development
1997
Abnormal gastrointestinal development in PDGF-A and PDGFR-α deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis
2000
FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
1998
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle
1999
Early myotome specification regulates PDGFA expression and axial skeleton development
2000
Mitochondrial DNA mutations in disease and aging
2011
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice
2001
Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli
1998
Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice
1999
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Functional Blockade of Platelet-Derived Growth Factor Receptor-β but Not of Receptor-α Prevents Vascular Smooth Muscle Cell Accumulation in Fibrous Cap Lesions in Apolipoprotein E–Deficient Mice
2001
Works of Jan Törnell being referenced
Liver-Derived IGF-I is of Importance for Normal Carbohydrate and Lipid Metabolism
2001
Premature ageing in mice expressing defective mitochondrial DNA polymerase
2004 StandoutNature
Bovine growth hormone-transgenic mice have major alterations in hepatic expression of metabolic genes
2003
Myocardial hypertrophy in transgenic mice overexpressing the bovine growth hormone (bGH) gene
2000
Phenotypic screening of hepatocyte nuclear factor (HNF) 4-γ receptor knockout mice
2006
Prostate Development and Carcinogenesis in Prolactin Receptor Knockout Mice
2003
Importance of melanin-concentrating hormone receptor for the acute effects of ghrelin
2004
Epidermal Overexpression of Stratum Corneum Chymotryptic Enzyme in Mice: A Model for Chronic Itchy Dermatitis
2002
PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis
1996
Melanin-Concentrating Hormone Receptor 1 Deficiency Increases Insulin Sensitivity in Obese Leptin-Deficient Mice Without Affecting Body Weight
2006
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice
1999