Standout Papers

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation 2011 2026 2016 2021 385
  1. Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation (2011)
    Stuart A. Sievers, John Karanicolas et al. Nature

Citation Impact

Citing Papers

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
2010
Structure-based inhibitors of amyloid beta core suggest a common interface with tau
2019
Gene for Chinese Rhesus Macaque DC-SIGN Predicts the Existence of A But Not B Isoforms of the Protein
2002
Distribution and Immunophenotype of DC-SIGN-Expressing Cells in SIV-Infected and Uninfected Macaques
2002
TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine
2013
Cell type-dependent retention and transmission of HIV-1 by DC-SIGN
2003
gp340 Expressed on Human Genital Epithelia Binds HIV-1 Envelope Protein and Facilitates Viral Transmission
2007 StandoutNobel
Syndecan Captures, Protects, and Transmits HIV to T Lymphocytes
2003
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses
2020
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
Placental expression of DC‐SIGN may mediate intrauterine vertical transmission of HIV
2001
Intrinsic Cellular Defenses against Human Immunodeficiency Viruses
2012
Evolutionary conflicts between viruses and restriction factors shape immunity
2012
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity
2012
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Identification of Different Binding Sites in the Dendritic Cell-specific Receptor DC-SIGN for Intercellular Adhesion Molecule 3 and HIV-1
2002
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
2013 Nature
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
2003 Standout
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
2021
Characterization of Regulatory Elements on the Promoter Region of p16INK4a That Contribute to Overexpression of p16 in Senescent Fibroblasts
2001
Chemokines and chemokine receptors: an overview
2009
Tau in physiology and pathology
2015 Standout
Protein folding and de novo protein design for biotechnological applications
2013
DC-SIGN and DC-SIGNR Bind Ebola Glycoproteins and Enhance Infection of Macrophages and Endothelial Cells
2002
Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN
2001
HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread
2002
The coming of age of de novo protein design
2016 StandoutNatureNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Immunity, Inflammation, and Cancer
2010 Standout
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection
2013 Nature
Glycosylation in health and disease
2019
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
2009
Inhibition of HIV-1 Particle Assembly by 2′,3′-Cyclic-Nucleotide 3′-Phosphodiesterase
2012 StandoutNobel
HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells
2009
The Amyloid State of Proteins in Human Diseases
2012 Standout
Interferon-inducible LY6E Protein Promotes HIV-1 Infection
2017
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
BST-2/tetherin: Structural biology, viral antagonism, and immunobiology of a potent host antiviral factor
2012
Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
2012
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
2016
CXCR3 ligands in disease and therapy
2014
Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2
2009
Diversity of receptors binding HIV on dendritic cell subsets
2002
Autophagy in immunity and inflammation
2011 StandoutNature
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Tau pathology and neurodegeneration
2013
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Simian immunodeficiency virus dramatically alters expression of homeostatic chemokines and dendritic cell markers during infection in vivo
2003
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
A family of multicyclic indolosesquiterpenes from a bacterial endophyte
2011
The Supramolecular Chemistry of β-Sheets
2013
Volitional aspects of achievement motivation and learned helplessness: toward a comprehensive theory of action control.
1984
Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro
2002 StandoutNobel
DC-SIGN (CD209) Expression Is IL-4 Dependent and Is Negatively Regulated by IFN, TGF-β, and Anti-Inflammatory Agents
2002
Expression of DC-SIGN by Dendritic Cells of Intestinal and Genital Mucosae in Humans and Rhesus Macaques
2002
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species Transmission
2009
Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins
2015
Quantitative Expression and Virus Transmission Analysis of DC-SIGN on Monocyte-Derived Dendritic Cells
2002
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
cisExpression of DC-SIGN Allows for More Efficient Entry of Human and Simian Immunodeficiency Viruses via CD4 and a Coreceptor
2001
Constructing arrays of proteins
2013
DC-SIGN and DC-SIGNR: helping hands for HIV
2001
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines
2022
DC-SIGN and DC-SIGNR Interact with the Glycoprotein of Marburg Virus and the S Protein of Severe Acute Respiratory Syndrome Coronavirus
2004
Subset of DC-SIGN+ dendritic cells in human blood transmits HIV-1 to T lymphocytes
2002
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Adaptation to the Interferon-Induced Antiviral State by Human and Simian Immunodeficiency Viruses
2013
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The theory of planned behavior
1991 Standout
Novel Member of the CD209 ( DC-SIGN ) Gene Family in Primates
2002
DC-SIGN from African Green Monkeys Is Expressed in Lymph Nodes and Mediates Infection intransof Simian Immunodeficiency Virus SIVagm
2003 StandoutNobel
β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR
2012
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
HIV-1 Selectively Infects a Subset of Nonmaturing BDCA1-Positive Dendritic Cells in Human Blood
2006 StandoutNobel
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
2009
Capture and Transfer of Simian Immunodeficiency Virus by Macaque Dendritic Cells Is Enhanced by DC-SIGN
2002
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein
2009
Inhibition of Human Immunodeficiency Virus Type 1 Env-Mediated Fusion by DC-SIGN
2003
Breakthrough Infections of SARS-CoV-2 Gamma Variant in Fully Vaccinated Gold Miners, French Guiana, 2021
2021
Binding of Human Immunodeficiency Virus Type 1 to Immature Dendritic Cells Can Occur Independently of DC-SIGN and Mannose Binding C-Type Lectin Receptors via a Cholesterol-Dependent Pathway
2003
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Characterization of the Alpha Interferon-Induced Postentry Block to HIV-1 Infection in Primary Human Macrophages and T Cells
2010
Functional and Antigenic Characterization of Human, Rhesus Macaque, Pigtailed Macaque, and Murine DC-SIGN
2001
Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR
2003 StandoutNobel
Structural Basis for Selective Recognition of Oligosaccharides by DC-SIGN and DC-SIGNR
2001 Science
Simian Immunodeficiency Virus Utilizes Human and Sooty Mangabey but Not Rhesus Macaque STRL33 for Efficient Entry
2000
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Differential Transmission of Human Immunodeficiency Virus Type 1 by Distinct Subsets of Effector Dendritic Cells
2002
CD4-Independent Use of Rhesus CCR5 by Human Immunodeficiency Virus Type 2 Implicates an Electrostatic Interaction between the CCR5 N Terminus and the gp120 C4 Domain
2001
C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans
2002
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2
2021
Functional Evaluation of DC-SIGN Monoclonal Antibodies Reveals DC-SIGN Interactions with ICAM-3 Do Not Promote Human Immunodeficiency Virus Type 1 Transmission
2002
Computational design of a symmetric homodimer using β-strand assembly
2011
The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells
2002
DC-SIGN Interactions with Human Immunodeficiency Virus: Virus Binding and Transfer Are Dissociable Functions
2001
Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN
2002
The Decreased Replicative Capacity of Simian Immunodeficiency Virus SIVmac239ΔnefIs Manifest in Cultures of Immature Dendritic Cells and T Cells
2000 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo
2011
Differential N-Linked Glycosylation of Human Immunodeficiency Virus and Ebola Virus Envelope Glycoproteins Modulates Interactions with DC-SIGN and DC-SIGNR
2002 StandoutNobel
Genetic Dissection of the Host Tropism of Human-Tropic Pathogens
2015
The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120
2002

Works of Jan Münch being referenced

LSECtin interacts with filovirus glycoproteins and the spike protein of SARS coronavirus
2005
SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies
2021
Role of Nef in primate lentiviral immunopathogenesis
2008
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1
2006
Xiamycin, a pentacyclic indolosesquiterpene with selective anti-HIV activity from a bacterial mangrove endophyte
2010
Development of a Self-Inactivating, Minimal Lentivirus Vector Based on Simian Immunodeficiency Virus
2000
Inefficient Nef-Mediated Downmodulation of CD3 and MHC-I Correlates with Loss of CD4+ T Cells in Natural SIV Infection
2008
TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition
2014
Aminoquinoline Surfen Inhibits the Action of SEVI (Semen-derived Enhancer of Viral Infection)
2009
Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen
2014
Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein
2012
Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists
2009
Peptides Released by Physiological Cleavage of Semen Coagulum Proteins Form Amyloids that Enhance HIV Infection
2011
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Analysis of nuclear actin by overexpression of wild-type and actin mutant proteins
2013
Platelet activation suppresses HIV-1 infection of T cells
2013
Co‐receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo
1999
DC-SIGN Interactions with Human Immunodeficiency Virus Type 1 and 2 and Simian Immunodeficiency Virus
2001
Nef Enhances Human Immunodeficiency Virus Type 1 Infectivity and Replication Independently of Viral Coreceptor Tropism
2002
The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection
2008
Contribution of Vpu, Env, and Nef to CD4 Down-Modulation and Resistance of Human Immunodeficiency Virus Type 1-Infected T Cells to Superinfection
2006
Nef-Mediated Enhancement of Virion Infectivity and Stimulation of Viral Replication Are Fundamental Properties of Primate Lentiviruses
2007
SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans
2020
The Human Immunodeficiency Virus Type 1nefGene Can to a Large Extent Replace Simian Immunodeficiency VirusnefIn Vivo
1999
Down-Modulation of Mature Major Histocompatibility Complex Class II and Up-Regulation of Invariant Chain Cell Surface Expression Are Well-Conserved Functions of Human and Simian Immunodeficiency Virus nef Alleles
2003
Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties
2000
Rankless by CCL
2026