Jan Grünewald

A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome

Expanding chemistry through in vitro and in vivo biocatalysis

Peptide Macrocyclization:  The Reductase of the Nostocyclopeptide Synthetase Triggers the Self-Assembly of a Macrocyclic Imine

Chemo- and Regioselective Peptide Cyclization Triggered by the N-Terminal Fatty Acid Chain Length:  The Recombinant Cyclase of the Calcium-Dependent Antibiotic from Streptomyces coelicolor