Citation Impact
Citing Papers
What is the total number of protein molecules per cell volume? A call to rethink some published values
2013
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
2006 StandoutScienceNobel
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ
2008 StandoutNobel
Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher
2015
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation?
2007
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards
2014
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
2011 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
An Inhibitory Activity in Human Cells Restricts the Function of an Avian-like Influenza Virus Polymerase
2008 StandoutNobel
A general method to improve fluorophores for live-cell and single-molecule microscopy
2015
Chromosome structure: improved immunolabeling for electron microscopy
2005
Active genes dynamically colocalize to shared sites of ongoing transcription
2004
STRING v9.1: protein-protein interaction networks, with increased coverage and integration
2012 Standout
FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know?
2010
A Cul3-Based E3 Ligase Removes Aurora B from Mitotic Chromosomes, Regulating Mitotic Progression and Completion of Cytokinesis in Human Cells
2007
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Cell type– and brain region–resolved mouse brain proteome
2015
In vivo dynamics of RNA polymerase II transcription
2007
Packaging the Genome: the Structure of Mitotic Chromosomes
2007
Three ways to make a vesicle
2000
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
2008 Nature
The multifunctional nucleolus
2007
Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens
2012 StandoutNobel
Retention of Cytochrome b5 in the Endoplasmic Reticulum Is Transmembrane and Luminal Domain-dependent
1998
Phase separation drives heterochromatin domain formation
2017 Nature
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Folding, Assembly and Subcellular Localization of Hepatitis C Virus Glycoproteins
2000
Automated Image Analysis for High-Content Screening and Analysis
2010
Lifeact: a versatile marker to visualize F-actin
2008 Standout
Mitotic chromosome structure and condensation
2006
Fluorescent labels for proteomics and genomics
2006
Global Proteome Analysis of the NCI-60 Cell Line Panel
2013
Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells
2009
Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat
2011 StandoutNobel
Studying protein dynamics in living cells
2001
Trafficking and localisation of resident Golgi glycosylation enzymes
2001
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Transcription Dynamics
2009
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Regulation of endoplasmic reticulum turnover by selective autophagy
2015 Nature
Single-molecule imaging of transcription factor binding to DNA in live mammalian cells
2013
The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription
2005
Global Identification of Modular Cullin-RING Ligase Substrates
2011
Nucleolar proteome dynamics
2005 Nature
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
A Method for the Acute and Rapid Degradation of Endogenous Proteins
2017
Nucleation of nuclear bodies by RNA
2011
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
2016
Repair of Strand Breaks by Homologous Recombination
2013
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
2015
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Toward automatic phenotyping of developing embryos from videos
2005
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
2015 Standout
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
The Perseus computational platform for comprehensive analysis of (prote)omics data
2016 Standout
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Reducing the Environmental Sensitivity of Yellow Fluorescent Protein
2001 StandoutNobel
Fiji: an open-source platform for biological-image analysis
2012 Standout
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells
2014
Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit
2008
Golgi Membranes Remain Segregated from the Endoplasmic Reticulum during Mitosis in Mammalian Cells
2004
Genome organization in and around the nucleolus
2011
Highway to the inner nuclear membrane: rules for the road
2007 Nobel
Mass spectrometric protein maps for biomarker discovery and clinical research
2013
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly
2011
Concentrative Export from the Endoplasmic Reticulum of the γ-Aminobutyric Acid Transporter 1 Requires Binding to SEC24D
2007
Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
2007
Modular peptide binding: From a comparison of natural binders to designed armadillo repeat proteins
2013
Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor
2018
Deep learning
2015 StandoutNatureNobel
Fluorescent Proteins as Proteomic Probes
2005
Imaging in Systems Biology
2007
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
2013 Nobel
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin
2017
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells
2012
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
Neural stem and progenitor cells shorten S-phase on commitment to neuron production
2011
Expression of fluorescently tagged connexins: a novel approach to rescue function of oligomeric DsRed‐tagged proteins1
2001
The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription
2008
Elongation by RNA polymerase II: the short and long of it
2004
Ligand binding by repeat proteins: natural and designed
2008
Crystal structure of the polymerase PAC–PB1N complex from an avian influenza H5N1 virus
2008 Nature
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Comparative analysis and application of fluorescent protein-tagged connexins
2001
Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
2009
Inter-homologue repair in fertilized human eggs?
2018 Nature
Condensin I binds chromatin early in prophase and displays a highly dynamic association with Drosophila mitotic chromosomes
2007
Role of Cyclin G-associated Kinase in Uncoating Clathrin-coated Vesicles from Non-neuronal Cells
2000
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Cell cycle maintenance and biogenesis of the Golgi complex
2000
Regulating protein degradation by ubiquitination
1997
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
The ER in 3D: a multifunctional dynamic membrane network
2011
Cleavage of the siRNA passenger strand during RISC assembly in human cells
2006
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails
2008
Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy
2006 StandoutNobel
Avian Influenza A Virus Polymerase Association with Nucleoprotein, but Not Polymerase Assembly, Is Impaired in Human Cells during the Course of Infection
2008
BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living Cells
2010
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Micromechanical Studies of Mitotic Chromosomes
2003
Formation of stacked ER cisternae by low affinity protein interactions
2003
Organellar relationships in the Golgi region of the pancreatic beta cell line, HIT-T15, visualized by high resolution electron tomography
2001
Quality Control by DNA Repair
1999 StandoutScienceNobel
Dynamic Sorting of Nuclear Components into Distinct Nucleolar Caps during Transcriptional Inhibition
2005
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins
2004
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Development and Use of Fluorescent Protein Markers in Living Cells
2003 Science
Physical and functional association of glycolipid N -acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus
2001
Partitioning of the Matrix Fraction of the Golgi Apparatus During Mitosis in Animal Cells
2002 Science
Assemblages: Functional units formed by cellular phase separation
2014
An Ordered Inheritance Strategy for the Golgi Apparatus: Visualization of Mitotic Disassembly Reveals a Role for the Mitotic Spindle
1998
Multicolor and Electron Microscopic Imaging of Connexin Trafficking
2002 StandoutScienceNobel
Active recycling of yeast Golgi mannosyltransferase complexes through the endoplasmic reticulum
2000 StandoutNobel
Dynamics of putative raft-associated proteins at the cell surface
2004
Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-dependent Removal from ER Membranes
1998 StandoutNobel
Protein localization studies in the age of ‘Omics’
2005
Adaptive strategies of the influenza virus polymerase for replication in humans
2009 StandoutNobel
3D imaging of Sox2 enhancer clusters in embryonic stem cells
2014 StandoutNobel
UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS
1998
Recycling of Golgi-resident Glycosyltransferases through the ER Reveals a Novel Pathway and Provides an Explanation for Nocodazole-induced Golgi Scattering
1998
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Metal‐dependent assembly of a protein nano‐cage
2019
Movement of Bax from the Cytosol to Mitochondria during Apoptosis
1997 Standout
Action of DNA Repair Endonuclease ERCC1/XPF in Living Cells
1999 Science
Differential Polymerase Activity in Avian and Mammalian Cells Determines Host Range of Influenza Virus
2007
Functional Mapping of the Zebrafish Early Embryo Proteome and Transcriptome
2014
The localization and phosphorylation of p47 are important for Golgi disassembly–assembly during the cell cycle
2003
ProteinN-Glycosylation along the Secretory Pathway: Relationship to Organelle Topography and Function, Protein Quality Control, and Cell Interactions
2002
Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum
2001
Force Generation, Transmission, and Integration during Cell and Tissue Morphogenesis
2011
Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus
2014
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
2002
Identification of Transcription Complexes that Contain the Double Bromodomain Protein Brd2 and Chromatin Remodeling Machines
2006
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
The Dynamics of Golgi Protein Traffic Visualized in Living Yeast Cells
1998
BAF: roles in chromatin, nuclear structure and retrovirus integration
2004
Translocation of C. elegans CED-4 to Nuclear Membranes During Programmed Cell Death
2000 StandoutScienceNobel
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
2016 StandoutNobel
Brd4 Is Required for Recovery from Antimicrotubule Drug-induced Mitotic Arrest: Preservation of Acetylated Chromatin
2005
System wide analyses have underestimated protein abundances and the importance of transcription in mammals
2014
Light Microscopy Techniques for Live Cell Imaging
2003 Science
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Evidence that the entire Golgi apparatus cycles in interphase HeLa cells
2001
Works of Jan Ellenberg being referenced
NuSAP, a Mitotic RanGTP Target That Stabilizes and Cross-links Microtubules
2006
Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells
2004
Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos
2018 Science
High-throughput fluorescence microscopy for systems biology
2006
Nucleocytoplasmic transport: Diffusion channel or phase transition?
2001
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
2012
Kinetic Analysis of Secretory Protein Traffic and Characterization of Golgi to Plasma Membrane Transport Intermediates in Living Cells
1998
Roles of Polo-like Kinase 1 in the Assembly of Functional Mitotic Spindles
2004
Condensin I Stabilizes Chromosomes Mechanically through a Dynamic Interaction in Live Cells
2006
Regulation of Sister Chromatid Cohesion between Chromosome Arms
2004
Self-Organization of MTOCs Replaces Centrosome Function during Acentrosomal Spindle Assembly in Live Mouse Oocytes
2007
Dynamics of nuclear pore complex organization through the cell cycle
2004
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit
2007
Dynamics and retention of misfolded proteins in native ER membranes
2000
Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin
2009
Automated Analysis of the Mitotic Phases of Human Cells in 3D Fluorescence Microscopy Image Sequences
2006
Golgi Membranes Are Absorbed into and Reemerge from the ER during Mitosis
1999
Measuring structural dynamics of chromosomes in living cells by fluorescence microscopy
2006
Dynamics and Mobility of Nuclear Envelope Proteins in Interphase and Mitotic Cells Revealed by Green Fluorescent Protein Chimeras
1999
Mapping the dynamic organization of the nuclear pore complex inside single living cells
2004
Monitoring the permeability of the nuclear envelope during the cell cycle
2005
Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase
2007
The Transmembrane Domain of a Carboxyl-terminal Anchored Protein Determines Localization to the Endoplasmic Reticulum
1997
Dual-colour imaging with GFP variants
1999
Live-Cell Imaging Reveals a Stable Cohesin-Chromatin Interaction after but Not before DNA Replication
2006
Cyclic, Proteasome-Mediated Turnover of Unliganded and Liganded ERα on Responsive Promoters Is an Integral Feature of Estrogen Signaling
2003
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
2009
A New Model for Asymmetric Spindle Positioning in Mouse Oocytes
2008
A fractal model for nuclear organization: current evidence and biological implications
2012
Ki-67 acts as a biological surfactant to disperse mitotic chromosomes
2016 Nature
Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes
2011
Global Chromosome Positions Are Transmitted through Mitosis in Mammalian Cells
2003
Dissecting the Contribution of Diffusion and Interactions to the Mobility of Nuclear Proteins
2005
A contractile nuclear actin network drives chromosome congression in oocytes
2005 Nature
Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes in live cells
2001
Remodelling the walls of the nucleus
2002
Automatic Identification of Subcellular Phenotypes on Human Cell Arrays
2004
Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes
2003
Nuclear Membrane Dynamics and Reassembly in Living Cells: Targeting of an Inner Nuclear Membrane Protein in Interphase and Mitosis
1997
The quantitative proteome of a human cell line
2011
A Bromodomain Protein, MCAP, Associates with Mitotic Chromosomes and Affects G2-to-M Transition
2000
Mechanisms of nuclear pore complex assembly – two different ways of building one molecular machine
2017
Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells
2001
Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei
2004
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization
2003
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells
2001
Retrograde Transport of Golgi-localized Proteins to the ER
1998
ZAP-70 Association with T Cell Receptor ζ (TCRζ): Fluorescence Imaging of Dynamic Changes upon Cellular Stimulation
1998
Distinct functions of condensin I and II in mitotic chromosome assembly
2004
Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein
1999
Two-Color Green Fluorescent Protein Time-Lapse Imaging
1998
The Entire Nup107-160 Complex, Including Three New Members, Is Targeted as One Entity to Kinetochores in Mitosis
2004