Citation Impact
Citing Papers
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers
2018 StandoutNobel
IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function
2016
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
2009 StandoutNobel
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
2013 StandoutNobel
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
2011
ICOS Mediates the Development of Insulin-Dependent Diabetes Mellitus in Nonobese Diabetic Mice
2008
Regulatory T cells in autoimmune kidney diseases and transplantation
2023 StandoutNobel
Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
2022
Microbiota in health and diseases
2022 Standout
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells
2007
IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5
2007
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes
2017 StandoutNobel
Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family
2016
Genetic susceptibility to type 1 diabetes
2005
Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity
2021 Standout
Etiology of Type 1 Diabetes
2010
Co-stimulatory and Co-inhibitory Pathways in Autoimmunity
2016
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
The Generation of Donor-Specific CD4+CD25++CD45RA+ Naive Regulatory T Cells in Operationally Tolerant Patients After Pediatric Living-Donor Liver Transplantation
2010 StandoutNobel
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation
2011 StandoutNobel
The Vertebrate Genome Annotation (Vega) database
2004
In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines
2017
The interactions of dendritic cells with antigen-specific, regulatory T cells that suppress autoimmunity
2006 StandoutNobel
Genetics, pathogenesis and clinical interventions in type 1 diabetes
2010 Nature
Tolerance and Autoimmunity: Lessons at the Bedside of Primary Immunodeficiencies
2007
Skeletal infections: microbial pathogenesis, immunity and clinical management
2022 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 StandoutNobel
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Inflammation and tumor progression: signaling pathways and targeted intervention
2021 Standout
Emerging possibilities in the development and function of regulatory T cells
2006 StandoutNobel
Regulatory T cells: how do they suppress immune responses?
2009 StandoutNobel
CTLA4 gene polymorphism and autoimmunity
2005
The Stages of Type 1A Diabetes
2005
Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes
2008
Type 1 diabetes
2013 Standout
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
2016 Standout
Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
2009 StandoutNobel
Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice
2009 StandoutNobel
Ensembl BioMarts: a hub for data retrieval across taxonomic space
2011 Standout
Regulatory T cells in the treatment of disease
2018
Premature CD4+ T Cell Aging and Its Contribution to Lymphopenia-Induced Proliferation of Memory Cells in Autoimmune-Prone Non-Obese Diabetic Mice
2014
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression
2020 StandoutNobel
Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)
2010 StandoutNobel
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
The gut–liver axis and the intersection with the microbiome
2018
Checkpoints in lymphocyte development and autoimmune disease
2009
The vertebrate genome annotation (Vega) database
2007
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Pathogenesis of Type 1 Diabetes Mellitus and Rodent Experimental Models
2018
The role of costimulation in antibody deficiencies: ICOS and common variable immunodeficiency
2009
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells
2012 StandoutNobel
Follicular Helper CD4 T Cells (TFH)
2011 Standout
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Altered phenotype and function of dendritic cells in children with type 1 diabetes
2005
Evolution of the immune system in humans from infancy to old age
2015 Standout
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo
2006
THE B7 FAMILY REVISITED
2005 Standout
Population Structure and Eigenanalysis
2006 Standout
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
The Diabetes Susceptibility Locus Idd5.1 on Mouse Chromosome 1 Regulates ICOS Expression and Modulates Murine Experimental Autoimmune Encephalomyelitis
2004
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Low-Dose IL-2 Therapy in Transplantation, Autoimmunity, and Inflammatory Diseases
2019
Innate Immunity to Staphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections
2018
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice
2020
The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function
2011
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Effects of interleukin-2 in immunostimulation and immunosuppression
2019
Sex-Specific Effect of Insulin-Dependent Diabetes 4 on Regulation of Diabetes Pathogenesis in the Nonobese Diabetic Mouse
2005
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
2011
No Alterations in the Frequency of FOXP3+ Regulatory T-Cells in Type 1 Diabetes
2007
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans
2012 StandoutNobel
Hyper-Progressive Disease: The Potential Role and Consequences of T-Regulatory Cells Foiling Anti-PD-1 Cancer Immunotherapy
2020 StandoutNobel
Works of Jan Clark being referenced
Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells
2014
Type 1 diabetes genes and pathways shared by humans and NOD mice
2005
Identification of Cd101 as a Susceptibility Gene for Novosphingobium aromaticivorans-Induced Liver Autoimmunity
2011
Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles
2014
Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses SupportCtla4andNramp1as Candidates forIdd5.1andIdd5.2in the Nonobese Diabetic Mouse
2004