Citation Impact
Citing Papers
Prospective identification of tumorigenic breast cancer cells
2003 Standout
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
2003 Standout
Gene Expression Profiling of Gliomas Strongly Predicts Survival
2004
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.
1998
Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma
1999
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors
2001
IDH1andIDH2Mutations in Gliomas
2009 Standout
Molecular genetic alterations in glioblastomas with oligodendroglial component
2001
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
The WHO Classification of Tumors of the Nervous System
2002 Standout
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
Frequent Co‐Alterations of TP53, p16/CDKN2A, p14ARF, PTEN Tumor Suppressor Genes in Human Glioma Cell Lines.
1999
Allelic losses on chromosome arm 10q and mutation of the PTEN ( MMAC1 ) tumour suppressor gene in primary and metastatic malignant melanomas
2000
Ovarian cancer
2014 Standout
Epidemiology and etiology of meningioma
2010
Hypermethylation and Transcriptional Downregulation of the Carboxyl-Terminal Modulator Protein Gene in Glioblastomas
2004
Analysis of the IDH1 codon 132 mutation in brain tumors
2008
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Genetic Alterations and Aberrant Expression of Genes Related to the Phosphatidyl‐lnositol‐3′‐Kinase/Protein Kinase B (Akt) Signal Transduction Pathway in Glioblastomas
2003
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Primary and secondary glioblastomas: From concept to clinicaldiagnosis
1999
The Hallmarks of Cancer
2000 Standout
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
1998 StandoutNobel
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
The 1p-Encoded Protein Stathmin and Resistance of Malignant Gliomas to Nitrosoureas
2007
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis
2012
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Mechanisms of Disease: genetic predictors of response to treatment in brain tumors
2007
Functions of MDMX in the Modulation of the p53‐Response
2011
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers
2000
?Malignancy? in meningiomas
1999
Epidemiology of Brain Tumors
2007
Modulation of cellular apoptotic potential: contributions to oncogenesis
1999
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
2000 StandoutNature
Malignant Gliomas in Adults
2008 Standout
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
Mutations of the human PTEN gene
2000
Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas
1999
PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells
2008 StandoutNobel
Oligodendroglioma: Toward Molecular Definitions in Diagnostic Neuro-Oncology
2003
Neuroblastoma
2007 Standout
MicroRNA signatures in human cancers
2006 Standout
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
2006 StandoutNobel
Primary brain tumours in adults
2012 Standout
Glioblastomas with an Oligodendroglial Component: A Pathological and Molecular Study
2001
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
2006
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract
1999
Identification of human brain tumour initiating cells
2004 StandoutNature
MdmX Is a RING Finger Ubiquitin Ligase Capable of Synergistically Enhancing Mdm2 Ubiquitination
2002
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
2010
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Characterization of Gene Expression Profiles Associated with Glioma Progression Using Oligonucleotide-Based Microarray Analysis and Real-Time Reverse Transcription-Polymerase Chain Reaction
2003
Sirolimus for Kaposi's Sarcoma in Renal-Transplant Recipients
2005 Standout
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance
2001 StandoutNobel
The RASSF proteins in cancer; from epigenetic silencing to functional characterization
2009
Heterogeneity in Breast Cancer and the Problem of Relevance of Findings
1999
Muscle-Specific Pten Deletion Protects against Insulin Resistance and Diabetes
2005 StandoutNobel
PPM1D is a potential target for 17q gain in neuroblastoma.
2003
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
1999 Standout
Mutational analysis of the PTEN gene in gliomas: Molecular and pathological correlations
1999
MDMX: from bench to bedside
2007
Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.
2001
CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010
2013 Standout
Targeting Mdm2 and Mdmx in Cancer Therapy: Better Living through Medicinal Chemistry?
2009
Critical Roles of Pten in B Cell Homeostasis and Immunoglobulin Class Switch Recombination
2003 StandoutNobel
Quantitative analyses reveal the importance of regulated Hdmx degradation for P53 activation
2007
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
2013
Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
2003
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression
2001
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
1999
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
2007 Standout
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Cancerous stem cells can arise from pediatric brain tumors
2003 Standout
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
2014
Phenotype vs Genotype in the Evolution of Astrocytic Brain Tumors
2000
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
The Pten/PI3K pathway governs the homeostasis of Vα14iNKT cells
2006 StandoutNobel
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.
2000 StandoutNobel
Works of Jan Boström being referenced
Identification of Two Distinct Deleted Regions on the Short Arm of Chromosome 1 and Rare Mutation of theCDKN2CGene from 1p32 in Oligodendroglial Tumors
1999
Deletion mapping of the short arm of chromosome 1 identifies a common region of deletion distal to D1S496 in human meningiomas
1997
Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q.
1998
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification.
1999
Analysis of genomic alterations in benign, atypical, and anaplastic meningiomas: Toward a genetic model of meningioma progression
1997
MOLECULAR GENETICS OF MENINGIOMAS
2007
Molecular genetic analysis of giant cell glioblastomas.
1997