Citation Impact
Citing Papers
Adipose-specific deletion of autophagy-related gene 7 ( atg7 ) in mice reveals a role in adipogenesis
2009
PPARδ regulates glucose metabolism and insulin sensitivity
2006
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
2007 Standout
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
2005 StandoutScience
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Cold-Activated Brown Adipose Tissue in Healthy Men
2009 Standout
Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors
2014
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
FoxOs Function Synergistically to Promote Glucose Production
2010
FOXO1 Transrepresses Peroxisome Proliferator-activated Receptor γ Transactivation, Coordinating an Insulin-induced Feed-forward Response in Adipocytes
2009
Genetic determinants of hepatic steatosis in man
2011
Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease
2007
Adipose Subtype-Selective Recruitment of TLE3 or Prdm16 by PPARγ Specifies Lipid Storage versus Thermogenic Gene Programs
2013
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age
2007
Thiazolidinediones
2004 Standout
The Many Faces of PPARγ
2005
Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance
2016
Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
2007
Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production
2016
mTOR Signaling in Growth Control and Disease
2012 Standout
A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
2012 Nature
Inflammation and metabolic disorders
2006 StandoutNature
Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
2008
PPARs: Fatty acid sensors controlling metabolism
2012
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
2007
Identification and Importance of Brown Adipose Tissue in Adult Humans
2009 Standout
PPARγ‐dependent regulation of human macrophages in phagocytosis of apoptotic cells
2007
New Insights into the Integrated Physiology of Insulin Action
2004
PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein
2012
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Suppression of PPAR-γ attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes
2007
The Failing Heart — An Engine Out of Fuel
2007 Standout
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer
2016
Peroxisome proliferator-activated receptor γ in diabetes and metabolism
2004
Epigenetic codes of PPARγ in metabolic disease
2011
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
2012
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
2004 Standout
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity
2011
Dissociating fatty liver and diabetes
2012
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
2010 Standout
Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation
2008
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
2015
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Thiazolidinediones and PPARγ agonists: time for a reassessment
2012
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
2004
Lipid‐sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome
2011
Genomic and epigenomic regulation of adipose tissue inflammation in obesity
2013
IKK-β links inflammation to obesity-induced insulin resistance
2005
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
2007
PPAR gamma 2 Prevents Lipotoxicity by Controlling Adipose Tissue Expandability and Peripheral Lipid Metabolism
2007
PPAR and human metabolic disease
2006
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Functional Brown Adipose Tissue in Healthy Adults
2009 Standout
Intestinal‐specific PPARγ deficiency enhances tumorigenesis in ApcMin/+ mice
2006
PPARs and the complex journey to obesity
2004
JNK1 in Hematopoietically Derived Cells Contributes to Diet-Induced Inflammation and Insulin Resistance without Affecting Obesity
2007
STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells
2010
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
PPARγ: A Critical Determinant of Body Fat Distribution in Humans and Mice
2005
Glycemic Durability of Rosiglitazone, Metformin, or Glyburide Monotherapy
2006 Standout
Graves' Ophthalmopathy
2010 Standout
Nonalcoholic Fatty Liver Disease: Cytokine-Adipokine Interplay and Regulation of Insulin Resistance
2006
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity
2004
Unraveling the Regulation of Hepatic Metabolism by Insulin
2017
Insulin action and resistance in obesity and type 2 diabetes
2017
Autophagy in Human Health and Disease
2013 Standout
Cytosolic Phosphoenolpyruvate Carboxykinase Does Not Solely Control the Rate of Hepatic Gluconeogenesis in the Intact Mouse Liver
2007
Adiponectin: a relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity?
2005
PPARγ in the control of brown adipocyte differentiation
2005
Autophagy regulates adipose mass and differentiation in mice
2009
A Dominant Negative Peroxisome Proliferator-activated Receptor-γ Knock-in Mouse Exhibits Features of the Metabolic Syndrome
2005
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
Decreased expression of hepatic glucokinase in type 2 diabetes
2014
PPAR-γ regulates osteoclastogenesis in mice
2007
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
2012
Proteasomal degradation of retinoid X receptor α reprograms transcriptional activity of PPARγ in obese mice and humans
2010
Bone marrow–specific Cap gene deletion protects against high-fat diet–induced insulin resistance
2007
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization
2015
Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice
2008
What We Talk About When We Talk About Fat
2014 Standout
Transcriptional regulation of hepatic lipogenesis
2015
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Desnutrin/ATGL Is Regulated by AMPK and Is Required for a Brown Adipose Phenotype
2011
Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones
2011
AKT/PKB Signaling: Navigating the Network
2017 Standout
Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling
2017
The Hallmarks of Aging
2013 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
Depletion of fat-resident Treg cells prevents age-associated insulin resistance
2015 Nature
Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin
2004
Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene
2011
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
2012 Nature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration
2008
Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice
2009
Forming functional fat: a growing understanding of adipocyte differentiation
2011
Developmental Origin of Fat: Tracking Obesity to Its Source
2007
Insulin signaling to hepatic lipid metabolism in health and disease
2011
Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance
2013
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
Considerations in the Design of Hyperinsulinemic-Euglycemic Clamps in the Conscious Mouse
2006
Regulatory circuits controlling white versus brown adipocyte differentiation
2006
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
2008
A Role for Sphingolipids in Producing the Common Features of Type 2 Diabetes, Metabolic Syndrome X, and Cushing’s Syndrome
2005
Cardiomyocyte-Specific Knockout and Agonist of Peroxisome Proliferator–Activated Receptor-γ Both Induce Cardiac Hypertrophy in Mice
2005
Nuclear Receptor Signaling and Cardiac Energetics
2004
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase
2006
Fat and Beyond: The Diverse Biology of PPARγ
2008 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Lipodystrophy Due to Adipose Tissue–Specific Insulin Receptor Knockout Results in Progressive NAFLD
2016
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Peroxisome Proliferator-Activated Receptor γ and Adipose Tissue—Understanding Obesity-Related Changes in Regulation of Lipid and Glucose Metabolism
2006
PPARγ activation in adipocytes is sufficient for systemic insulin sensitization
2009
Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism
2008
Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse
2004
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Peroxisome Proliferator-Activated Receptor-γ Calls for Activation in Moderation: Lessons from Genetics and Pharmacology
2004
Autophagy and Metabolism
2010 StandoutScience
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
2010
Macrophages, Inflammation, and Insulin Resistance
2010 Standout
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Mitochondrial dysfunction and insulin resistance: an update
2014
Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance
2005
Dysregulation of the Peroxisome Proliferator-Activated Receptor Target Genes by XPD Mutations
2005
Works of Jamie Le being referenced
FoxO1 Regulates Multiple Metabolic Pathways in the Liver
2006
Muscle-specific Pparg deletion causes insulin resistance
2003
Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance
2006
HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle
2013
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
2003
Myeloid-specific estrogen receptor α deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development
2011