Citation Impact
Citing Papers
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Improvement of a Potential Anthrax Therapeutic by Computational Protein Design
2011 StandoutNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Chemical genetics: tailoring tools for cell biology
2003
Clinical translation of angiogenesis inhibitors
2002 Standout
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
2001 StandoutNature
Amide bond formation: beyond the myth of coupling reagents
2008 Standout
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
From epoxomicin to carfilzomib: chemistry, biology, and medical outcomes
2013
Imaging in the era of molecular oncology
2008 StandoutNature
Syntheses of Fumagillin and Ovalicin
2010
Chemical Genetics
2003
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
Inhibition of tumor growth in a human neuroblastoma xenograft model with TNP-470
2000
HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
2005 StandoutNobel
The Hallmarks of Cancer
2000 Standout
The biology of VEGF and its receptors
2003 Standout
Pyrrolidinyl‐Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents
2007 Standout
Cancer genes and the pathways they control
2004 Standout
Protein‐Reactive Natural Products
2005
Efficient Solid‐Phase Synthesis of Peptide‐Based Phosphine Ligands: Towards Combinatorial Libraries of Selective Transition Metal Catalysts
2005 StandoutNobel
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Sequence and Analysis of Chromosome I of the Amitochondriate Intracellular Parasite Encephalitozoon cuniculi (Microspora)
2001
Inhibition of Angiogenesis by the Antifungal Drug Itraconazole
2007
Inflammation in atherosclerosis
2002 StandoutNature
Neuroblastoma
2007 Standout
Display cloning: functional identification of natural product receptors using cDNA-phage display
1999
Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools
2000
What We Talk About When We Talk About Fat
2014 Standout
Design and synthesis of highly potent fumagillin analogues from homology modeling for a human MetAP-2
2000
Structure and function of the methionine aminopeptidases
2000
The search for orally active medications through combinatorial chemistry
1998
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Atherosclerosis
2001 Standout
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
Structure–activity studies of cyclic ketone inhibitors of the serine protease plasmin: Design, synthesis, and biological activity
2006
In the Golden Age of Organocatalysis
2004 Standout
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Chemical Genetics
2006
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
2000 StandoutNobel
The allenic Alder-ene reaction: constitutional group selectivity and its application to the synthesis of ovalicin
2006
Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin
1998 Science
Chemistry of Polyvalent Iodine
2008 Standout
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Angiogenesis Inhibitors Endostatin or TNP-470 Reduce Intimal Neovascularization and Plaque Growth in Apolipoprotein E–Deficient Mice
1999
The antiangiogenic agent TNP-470 requires p53 and p21 CIP/WAF for endothelial cell growth arrest
2000
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters
2014 StandoutNobel
Addition of HOAt dramatically improves the effectiveness of pentafluorophenyl-based coupling reagents
1999
Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice
2004
Ascending dose‐controlled trial of beloranib, a novel obesity treatment for safety, tolerability, and weight loss in obese women
2013
Target Identification by Diazirine Photo‐Cross‐Linking and Click Chemistry
2009
The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase
1998
Synthesis of (−)-Fumagillin
1999
Mass spectrometry-based proteomics
2003 StandoutNature
An Essential Role of N-Terminal Arginylation in Cardiovascular Development
2002 Science
An efficient approach for monosulfide bridge formation in solid-phase peptide synthesis
2004
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
A Mechanism-Based Combination Therapy Reduces Local Tumor Growth and Metastasis in an Orthotopic Model of Prostate Cancer
2006
An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis–Hillman reaction
2001
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Microwave-Assisted Synthesis in Water as Solvent
2007 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470.
2003
Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice
1999 Science
Natural product and natural product derived drugs in clinical trials
2014 Standout
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
Printing Proteins as Microarrays for High-Throughput Function Determination
2000 StandoutScience
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Solid-Phase Library Synthesis, Screening, and Selection of Tight-Binding Reduced Peptide Bond Inhibitors of a RecombinantLeishmaniamexicanaCysteine Protease B
2002 StandoutNobel
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Transition Metal Catalyzed Cycloisomerizations of 1,n-Allenynes and -Allenenes
2011 Standout
DMSO‐Aided o‐Iodoxybenzoic Acid (IBX) Oxidation of Fmoc‐Protected Amino Alcohols
2007
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
2001 Standout
RGS4 and RGS5 are in vivo substrates of the N-end rule pathway
2005
A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold
2002 StandoutNobel
Synthesis and reactivity of N‐protected‐α‐amino aldehydes
2003
Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes
2002
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Works of James Wen being referenced
A systematic approach to the solid‐phase synthesis of linear and cyclic pseudopeptide libraries containing ψ[CH2NH] amide bond surrogates
1997
Synthesis and characterization of cyclic pseudopeptide libraries containing thiomethylene and thiomethylene-sulfoxide amide bond surrogates
1997
Synthesis of 9-fluorenylmethoxycarbonyl-protected amino aldehydes
1998
The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
1997
Towards the semi-synthesis of didemnin M. Solution and solid phase synthese of the pseudotetrapeptide: pGlu-Glnψ[COO]Ala-Pro-OH
1998