Standout Papers
Citation Impact
Citing Papers
Immune Rejection of Mouse Tumors Expressing Mutated Self
2009 StandoutNobel
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Relative Unidirectional Translation in an Artificial Molecular Assembly Fueled by Light
2013 StandoutNobel
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Genes responsible for human hereditary deafness: symphony of a thousand
1996
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
2008 Nature
Genetic Evidence for Selective Transport of Opsin and Arrestin by Kinesin-II in Mammalian Photoreceptors
2000
Mouse models to study inner ear development and hereditary hearing loss
2007
Hearing in Drosophila: Development of Johnston's organ and emerging parallels to vertebrate ear development
2005
Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6
2002
VISTA: computational tools for comparative genomics
2004 Standout
A forward-genetic approach for analysis of the immune system
2003 StandoutNobel
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex
2000
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
2005 StandoutNatureNobel
Mutation screening of USH3 gene (clarin‐1) in Spanish patients with Usher syndrome: low prevalence and phenotypic variability
2004
Retinitis Pigmentosa and Progressive Sensorineural Hearing Loss Caused by a C12258A Mutation in the Mitochondrial MTTS2 Gene
1999
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Mechanosensory hair cells express two molecularly distinct mechanotransduction channels
2016 StandoutNobel
A human homologue of Drosophila kelch associates with myosin‐VIIa in specialized adhesion junctions
2002
Mutations in the myosin VIIA gene cause non-syndromic recessive deafness
1997
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
Genetic approaches to mechanosensory transduction
1995
Linkage Studies of Non-Syndromic Recessive Deafness (NSRD) in a Family Originating from the Mirpur Region of Pakistan Maps DFNB1 Centromeric to D13S175
1996
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
Mouse ENU Mutagenesis
1999
Connexin-26 mutations in sporadic and inherited sensorineural deafness
1998
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
Highly Enantioselective Synthesis of 3‐Substituted Furanones by Palladium‐Catalyzed Kinetic Resolution of Unsymmetrical Allyl Acetates
2012 StandoutNobel
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness
2000
Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses
1999
USH3A transcripts encode clarin-1, a four-transmembrane-domain protein with a possible role in sensory synapses
2002
A genetic approach to understanding auditory function
2001
Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons
2004 StandoutNobel
Microtubule-Microfilament Synergy in the Cytoskeleton
1997
PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23
2003
NEW EMBO MEMBER'S REVIEW: On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention
2002
Reduced climbing and increased slipping adaptation in cochlear hair cells of mice with Myo7a mutations
2001
Molecular basis of mechanosensory transduction
2001 Nature
Mutational spectrum in Usher syndrome type II
2004
Tails of unconventional myosins
1999
Rho GTPases in cell biology
2002 StandoutNature
Mechanically Activated Ion Channels
2015 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk
1999
Sensorineural hearing loss in children
2005 Standout
Unconventional Myosin VIIA Is a Novel A-kinase-anchoring Protein
2000
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals
2004 StandoutNobel
A natural cytotoxic T cell response in a spontaneously regressing human melanoma targets a neoantigen resulting from a somatic point mutation
1999
Retinitis pigmentosa
2006 Standout
Expression of myosin VIIA during mouse embryogenesis
1997
Myosin VIIa as a common component of cilia and microvilli
1998
The elusive mechanotransduction machinery of hair cells
2015
Genetic Analysis of Vertebrate Sensory Hair Cell Mechanosensation: the Zebrafish Circler Mutants
1998 Nobel
Role of Rho family GTPases in epithelial morphogenesis
2002
The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
1995
Mutational Analysis of Motor Proteins
1996
The Deaf Jerker Mouse Has a Mutation in the Gene Encoding the Espin Actin-Bundling Proteins of Hair Cell Stereocilia and Lacks Espins
2000
A class VII unconventional myosin is required for phagocytosis
1999
The mutagenic action of N-ethyl-N-nitrosourea in the mouse
2000
Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D
2001
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
2000
Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor
2000 Standout
The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene
1997
Identification and molecular modelling of a mutation in the motor head domain of myosin VIIA in a family with autosomal dominant hearing impairment (DFNA11)
2004
From deafness genes to hearing mechanisms: harmony and counterpoint
2006
Analysis of Cell–Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer
2021
Adhering Junction Dynamics in the Testis Are Regulated by an Interplay of β1-Integrin and Focal Adhesion Complex-Associated Proteins
2003
Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse
2003
Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
1997 StandoutNature
Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome
2001
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
2001
Interactions in the network of Usher syndrome type 1 proteins
2004
Tonotopic Gradient in the Developmental Acquisition of Sensory Transduction in Outer Hair Cells of the Mouse Cochlea
2009
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Retinopathy induced in mice by targeted disruption of the rhodopsin gene
1997 StandoutNobel
Application of the AAA Reaction to the Synthesis of the Furanoside ofC-2-epi-Hygromycin A: A Total Synthesis ofC-2-epi-Hygromycin A
2002
Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer
2005 StandoutNobel
Probing the Functional Equivalence of Otoferlin and Synaptotagmin 1 in Exocytosis
2011 StandoutNobel
The Human EMAP-like Protein-70 (ELP70) Is a Microtubule Destabilizer That Localizes to the Mitotic Apparatus
2002
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease
2010
Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population
2005
Quiet as a mouse: dissecting the molecular and genetic basis of hearing
2008
Neurosensory mechanotransduction
2008 StandoutNobel
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
2002
Structural characterization of a dynein motor domain
1998 StandoutNobel
Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
2009 StandoutNobel
Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D
2001
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
Adherens Junction Dynamics in the Testis and Spermatogenesis
2003
A catechol- O -methyltransferase that is essential for auditory function in mice and humans
2008 StandoutNobel
THE MOLECULES OF MECHANOSENSATION
1997
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
A Millennial Myosin Census
2001
INHERITED HEARING DEFECTS IN MICE
1995
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
2005 StandoutScience
Gelsolin — evidence for a role in turnover of junction-related actin filaments in Sertoli cells
2002
Adaptation in Hair Cells
2000
Asymmetric Induction of Conduritols via AAA Reactions: Synthesis of the Aminocyclohexitol of Hygromycin A
2001
Correction of Deafness in shaker-2 Mice by an Unconventional Myosin in a BAC Transgene
1998 Science
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Unconventional Myosins in Inner-Ear Sensory Epithelia
1997
The Notch ligand Jagged1 is required for inner ear sensory development
2001
Unique and Multifunctional Adhesion Junctions in the Testis. Ectoplasmic Specializations.
2000
Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes
2004
Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
1995
Mechanoelectrical Transduction and Adaptation in Hair Cells of the Mouse Utricle, a Low-Frequency Vestibular Organ
1997
Molecular Genetics of Hearing Loss
2001
Molecular Genetics of Human Retinal Disease
1999
Deletion Mapping of the Head Tilt (het) Gene in Mice: A Vestibular Mutation Causing Specific Absence of Otoliths
1998
Defective calmodulin-dependent rapid apical endocytosis in zebrafish sensory hair cell mutants
1999
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction
1998 Science
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
2004 Standout
GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
2006 StandoutNobel
Dynein and plus-end microtubule-dependent motors are associated with specialized Sertoli cell junction plaques (ectoplasmic specializations)
2000
Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice.
2003
Regulation of Cell Polarity by Microtubules in Fission Yeast
1998 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions
2002
Asymmetric Transition-Metal-Catalyzed Allylic Alkylations: Applications in Total Synthesis
2003 Standout
Genetics of Sensory Mechanotransduction
2002 StandoutNobel
Structural Mechanism of Muscle Contraction
1999
Cell Junction Dynamics in the Testis: Sertoli-Germ Cell Interactions and Male Contraceptive Development
2002
Works of James Walsh being referenced
Hygromycin A, an antitreponemal substance. I. Screening method and therapeutic effect for Treponema hyodysenteriae-caused infection in CF-1 mice.
1987 StandoutNobel
Hygromycin A, an antitreponemal substance. II. Therapeutic effect for swine dysentery.
1987 StandoutNobel
CetZ tubulin-like proteins control archaeal cell shape
2014 Nature
Mutation analysis of the mouse myosin VIIA deafness gene
1997
A type VII myosin encoded by the mouse deafness gene shaker-1
1995 Nature
Effects of shaker-1 mutations on myosin-VIIa protein and mRNA expression
1997
Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells
1998
Unravelling the genetics of deafness.
1997
Defective myosin VIIA gene responsible for Usher syndrome type IB
1995 Nature
Effects of shaker‐1 mutations on myosin‐VIIa protein and mRNA expression
1997