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Citing Papers
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Sequence and expression of a frog brain complementary DNA encoding a kainate-binding protein
1989 Nature
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
1986
A 3-Mb Map of a Large Segmental Duplication Overlapping the α7-Nicotinic Acetylcholine Receptor Gene (CHRNA7) at Human 15q13–q14
2002
Myasthenia Gravis
1988
Mouse genetic models for prepulse inhibition: an early review
2002
Specific immunotherapeutic strategy for myasthenia gravis: targeted antigen-presenting cells
1992
Strategies for Treatment of Myasthenia Gravisa
1993
Functional Architecture of the Nicotinic Acetylcholine Receptor: From Electric Organ to Brain
1991
Functional architecture of the nicotinic acetylcholine receptor: A prototype of ligand-gated ion channels
1993
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels
2000
Hydrogen peroxide mediates amyloid β protein toxicity
1994 Standout
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
2002 StandoutNature
The expression of amyloid beta protein precursor protects nerve cells from β-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix
1993
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Rat α3/β4 Subtype of Neuronal Nicotinic Acetylcholine Receptor Stably Expressed in a Transfected Cell Line: Pharmacology of Ligand Binding and Function
1998
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit
1999
The T‐Cell Repertoire in Myasthenia Gravis Involves Multiple Cholinergic Receptor Epitopes
1992
Ligand‐gated ion channels in the enteric nervous system
2002
P2X receptors in peripheral neurons
2001
Myasthenia Gravis
1994 Standout
Spatial and temporal expression of acetylcholine receptor RNAs in innervated and denervated rat soleus muscle
1989
Increased levels of acetylcholine receptor α‐subunit mRNA in experimental autoimmune myasthenia gravis
1988
Acetylcholine receptor α-, β-, γ-, and δ-subunit mRNA levels are regulated by muscle activity
1988
T‐Helper Epitopes on Human Nicotinic Acetylcholine Receptor in Myasthenia Gravisa
1993
Molecular physiology of p2x receptors and atp signalling at synapses
2001
T cells from normal and myasthenic individuals recognize the human acetylcholine receptor: Heterogeneity of antigenic sites on the α‐subunit
1992
Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function
2000
Developmental regulation of five subunit specific mRNAs encoding acetylcholine receptor subtypes in rat muscle
1989 StandoutNobel
State-dependent cross-inhibition between transmitter-gated cation channels
2000 Nature
Neural regulation of mRNA for the α-subunit of acetylcholine receptors: Role of neuromuscular transmission
1989
Quantitative analysis of both protein expression and serine / threonine post‐translational modifications through stable isotope labeling with dithiothreitol
2005
Human muscle acetylcholine receptor reactive T and B lymphocytes in the peripheral blood of patients with myasthenia growth
1993
Neuronal nicotinic receptors: from structure to pathology
2004
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Expression of the genes coding for glutamic acid decarboxylase in pluripotent cell lines
1993
Protein kinase C and F‐actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G‐proteins and amyloid beta protein
1996
Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
1995
Molecular Neurobiology and Genetics: Investigation of Neural Function and Dysfunction
1998
Non‐additive interaction between nicotinic cholinergic and P2X purine receptors in guinea‐pig enteric neurons in culture
1998
Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)
2010
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Cloning by functional expression of a member of the glutamate receptor family
1989 Nature
Immunophilins in the Nervous System
1998
Distinct GABAA receptor α subunit mRNAs show differential patterns of expression in bovine brain
1988
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
β3: A New Member of Nicotinic Acetylcholine Receptor Gene Family Is Expressed in Brain
1989
Acetylcholine Receptor‐Specific Human T‐Lymphocyte Linesa
1987
Multiple differentiation of clonal teratocarcinoma stem cells following embryoid body formation in vitro
1975 StandoutNobel
Topographic organization of sensory projections to the olfactory bulb
1994 StandoutNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Negative Cross Talk between Anionic GABAAand Cationic P2X Ionotropic Receptors of Rat Dorsal Root Ganglion Neurons
2001
The primary structure of NG2, a novel membrane-spanning proteoglycan.
1991
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation
1986 StandoutNobel
Molecular Physiology of P2X Receptors
2002 Standout
Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.
1989
Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor.
1979 StandoutNobel
Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts
1981 Nature
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Point mutant mice with hypersensitive α4 nicotinic receptors show dopaminergic deficits and increased anxiety
2001
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
An assay for antibodies to human acetylcholine receptor in serum from patients with myasthenia gravis
1977
New cell surface antigens in rat defined by tumors of the nervous system.
1975
Neuronal α-Bungarotoxin Receptors Are α7 Subunit Homomers
2000
Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface.
1993
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxins
1998 Standout
Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes
1990 Science
Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.
1996
Cholinergic and GABAergic Inputs Drive Patterned Spontaneous Motoneuron Activity before Target Contact
1999
Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.
2003
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Localization of nicotinic acetylcholine receptor alpha-subunit transcripts during myogenesis and motor endplate development in the chick.
1989
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
1985
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Sox10, a Novel Transcriptional Modulator in Glial Cells
1998 Standout
Steps Toward Computer Analysis of Nucleotide Sequences
1980 StandoutScienceNobel
Free cytoplasmic Ca2+ and neurotransmitter release: studies on PC12 cells and synaptosomes exposed to alpha-latrotoxin.
1984 StandoutNobel
Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium
1993
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Neural Science
2000 StandoutNobel
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids
1986 StandoutNobel
Molecular probes for the development and plasticity of neural crest derivatives
1985 StandoutNobel
Neuronal nicotinic receptors: from structure to function
2001
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen
1984 Nature
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.
1976 Standout
[6] The growth of cells in serum-free hormone-supplemented media
1979
Myasthenia Gravis
1977
Growth factors and vitamin E modify neuronal glutamate toxicity.
1992
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.
1986
The neu oncogene encodes an epidermal growth factor receptor-related protein
1986 Nature
Induction of muscle genes in neural cells.
1984
Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings
2000 StandoutNobel
Putative neurotransmitters in clonal cell lines
1975 Nature
Growth of a rat neuroblastoma cell line in serum-free supplemented medium.
1979 Standout
Contact-Mediated Myogenesis and Increased Acetylcholinesterase Activity in Primary Cultures of Mouse Teratocarcinoma Cells
1974
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Cell surface antigens of clonal teratocarcinoma cells at various stages of differentiation
1975 StandoutNobel
Two functionally dependent acetylcholine subunits are encoded in a single Caenorhabditis elegans operon
1998 StandoutNobel
Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene
1982 Nature
Two dimensional gel electrophoresis and computer analysis of proteins synthesized by clonal cell lines.
1979
ATP Stimulates Sympathetic Transmitter Release via Presynaptic P2X Purinoceptors
1999
Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.
1988
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen.
1990
Acetylcholinesterase — new roles for an old actor
2001
Acetylcholine receptor-inducing factor from chicken brain increases the level of mRNA encoding the receptor alpha subunit.
1988
Synaptic Vesicle Depletion Correlates with Attenuated Synaptic Responses to Prolonged Repetitive Stimulation in Mice Lacking α-Synuclein
2002
Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro.
1975 StandoutNobel
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Molecular biology of GABA A receptors
1990
Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
1993
Localization of a novel v-erbB-related gene, c-erbB-2, on human chromosome 17 and its amplification in a gastric cancer cell line.
1986
Chemical Glycoproteomics
2016 StandoutNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Cytoskeletal Reorganization Induced by Engagement of the NG2 Proteoglycan Leads to Cell Spreading and Migration
1999
Cleft palate in mice with a targeted mutation in the γ-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67
1997 StandoutNobel
Works of James W. Patrick being referenced
Muscle acetylcholine receptor biosynthesis. Regulation by transcript availability.
1987
Altered baroreflex responses in α7 deficient mice
2000
Pharmacology of Neuronal Nicotinic Acetylcholine Receptor Subtypes
1997
Mice Homozygous for the L250T Mutation in the α7 Nicotinic Acetylcholine Receptor Show Increased Neuronal Apoptosis and Die Within 1 Day of Birth
2000
Amino Acid Determinants of α7 Nicotinic Acetylcholine Receptor Surface Expression
2000
The α-Bungarotoxin-binding Nicotinic Acetylcholine Receptor from Rat Brain Contains Only the α7 Subunit
1997
Contributions of N‐Linked Glycosylation to the Expression of a Functional α7‐Nicotinic Receptor in Xenopus Oocytes
1998
Increased Sensitivity to Nicotine-Induced Seizures in Mice Expressing the L250T α7 Nicotinic Acetylcholine Receptor Mutation
2002
Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area
1997
Excess “read-through” acetylcholinesterase attenuates but the “synaptic” variant intensifies neurodeterioration correlates
2000
Protein synthesis and secretion in a myogenic cell line
1973
Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents
1997
Cellular immunity to acetylcholine receptor in myasthenia gravis
1979
Multiorgan Autonomic Dysfunction in Mice Lacking the β2 and the β4 Subunits of Neuronal Nicotinic Acetylcholine Receptors
1999
Cellular Immunity in Myasthenia Gravis
1976
Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.
1987
Megacystis, mydriasis, and ion channel defect in mice lacking the α3 neuronal nicotinic acetylcholine receptor
1999
Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors
1991
α7 Nicotinic Receptor Subunits Are Not Necessary for Hippocampal-Dependent Learning or Sensorimotor Gating: A Behavioral Characterization of Acra7-Deficient Mice
1998
Clonal cell lines from the rat central nervous system
1974 Nature
Neuronal localization of the cyclophilin A protein in the adult rat brain
1996
Calcium Flux Through Predominantly Independent Purinergic ATP and Nicotinic Acetylcholine Receptors
1997