Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
A general-purpose protein design framework based on mining sequence–structure relationships in known protein structures
2019
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds
2020 StandoutNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Perturbing the energy landscape for improved packing during computational protein design
2020 StandoutNobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Recent advances in de novo protein design: Principles, methods, and applications
2021
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Improvements to Robotics-Inspired Conformational Sampling in Rosetta
2013
Highly active enzymes by automated combinatorial backbone assembly and sequence design
2018
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
2014
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Enhancements to the Rosetta Energy Function Enable Improved Identification of Small Molecules that Inhibit Protein-Protein Interactions
2015
Designing protein structures and complexes with the molecular modeling program Rosetta
2019
A Pareto-Optimal Refinement Method for Protein Design Scaffolds
2013 StandoutNobel
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Improved low-resolution crystallographic refinement with Phenix and Rosetta
2013 StandoutNobel
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
2012
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
2016
Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]
1995
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Protein sequence design with a learned potential
2022
Protein Structure Prediction and Design in a Biologically Realistic Implicit Membrane
2020
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Computational design of a homotrimeric metalloprotein with a trisbipyridyl core
2016 StandoutNobel
Relaxation of backbone bond geometry improves protein energy landscape modeling
2013 StandoutNobel
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Why reinvent the wheel? Building new proteins based on ready‐made parts
2016
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules
2016 StandoutNobel
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
De novo design of small beta barrel proteins
2023 StandoutNobel
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein
2019 StandoutNobel
The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
2017 StandoutNobel
Organopalladium intermediates in organic synthesis
1977
Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities
2014
Automating human intuition for protein design
2013 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Combined Covalent-Electrostatic Model of Hydrogen Bonding Improves Structure Prediction with Rosetta
2015 StandoutNobel
Cyclic Carbopalladation. A Versatile Synthetic Methodology for the Construction of Cyclic Organic Compounds
1996 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Works of James Thompson being referenced
Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement
2013 StandoutNobel
Phylogenetic Fate Mapping: Theoretical and Experimental Studies Applied to the Development of Mouse Fibroblasts
2008
Carbonylation reactions of ortho-palladation products of .alpha.-arylnitrogen derivatives
1975 StandoutNobel
The optimal application of forward and ninety‐degree light scatter in flow cytometry for the gating of mononuclear cells
1985