Citation Impact
Citing Papers
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B.
2003
Chromosome Abnormalities and Genetic Counseling
2011
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
2013 Standout
Treatment of kidney cancer
2009 StandoutNobel
Fluorescent In Situ Hybridization of DNA Probes in the Interphase and Metaphase Stages of the Cell Cycle
2012
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Effect of Imatinib Mesylate on Chronic Myelogenous Leukemia Hematopoietic Progenitor Cells
2003
Natural products: An evolving role in future drug discovery
2011 Standout
Genetic Evaluation of Cardiomyopathy—A Heart Failure Society of America Practice Guideline
2009
American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants
2011
Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2016 Standout
Neocentromeres: Role in Human Disease, Evolution, and Centromere Study
2002
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
Treatment of Obesity with Celastrol
2015 Standout
The in vitro micronucleus technique
2000 Standout
Heat shock protein 90: The cancer chaperone
2007
Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei
2000
HSP90 and the chaperoning of cancer
2005 Standout
The HUman MicroNucleus Project—An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans
1999
EGF–ERBB signalling: towards the systems level
2006 Standout
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay
2004
Targeting cancer with small molecule kinase inhibitors
2008 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
2007 StandoutNobel
Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents
2015 Standout
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
2013 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
2005 Standout
Targeting multiple signal transduction pathways through inhibition of Hsp90
2004
Cytokinesis-block micronucleus cytome assay
2007 Standout
Chaperoning Oncogenes: Hsp90 as a Target of Geldanamycin
2005
Revealing the world of RNA interference
2004 StandoutNatureNobel
What do human micronuclei contain?
2003
CNV Concordance in 1,097 MZ Twin Pairs
2015
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Health Supervision for Children With Down Syndrome
2011 Standout
CNVs: Harbingers of a Rare Variant Revolution in Psychiatric Genetics
2012
Heat shock protein 90
2003
Telomeres and chromosome instability
2006
Development of novel therapeutic strategies that target HIF-1
2006 StandoutNobel
Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2018 Standout
Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90
2005
Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity
2011 Standout
Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
2013
American College of Medical Genetics and Genomics: standards and guidelines for documenting suspected consanguinity as an incidental finding of genomic testing
2013
Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia
2005
Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma
2015 Standout
Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics – an update
2005
Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells
2004
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
2004
One-pot synthesis of polysubstituted pyrimidines
2005
Cotreatment with the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) enhances imatinib-induced apoptosis of Bcr-Abl–positive human acute leukemia cells
2003
Superior Activity of the Combination of Histone Deacetylase Inhibitor LAQ824 and the FLT-3 Kinase Inhibitor PKC412 against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3
2004
Inhibitors of HSP90 and other chaperones for the treatment of cancer
2004
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
2015 Standout
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells
2007
Histone deacetylase inhibitor LAQ824 both lowers expression and promotes proteasomal degradation of Bcr-Abl and induces apoptosis of imatinib mesylate-sensitive or -refractory chronic myelogenous leukemia-blast crisis cells.
2003
Coadministration of the heat shock protein 90 antagonist 17-allylamino- 17-demethoxygeldanamycin with suberoylanilide hydroxamic acid or sodium butyrate synergistically induces apoptosis in human leukemia cells.
2003
Structural Dynamics of Eukaryotic Chromosome Evolution
2003 StandoutScience
Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3
2004
Works of James Tepperberg being referenced
X chromosome inactivation and micronuclei in normal and Turner individuals
1997
Prenatal molecular cytogenetic diagnosis of partial tetrasomy 10p due to neocentromere formation in an inversion duplication analphoid marker chromosome
2000
College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysis
2011
Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: a susceptibility region for neurological dysfunction including developmental and language delay
2011
UPD detection using homozygosity profiling with a SNP genotyping microarray
2011
Oncogene amplification in transforming myelodysplasia
2005
Variability in interpreting and reporting copy number changes detected by array-based technology in clinical laboratories
2009
Section E9 of the American College of Medical Genetics technical standards and guidelines: Fluorescence in situ hybridization
2011
Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin.
2002