Standout Papers

A role for Dicer in immune regulation 2006 2026 2012 2019 446
  1. A role for Dicer in immune regulation (2006)
    Bradley S. Cobb, Arnulf Hertweck et al. The Journal of Experimental Medicine
  2. A role for Dicer in immune regulation (2006)
    Bradley S. Cobb, Arnulf Hertweck et al. The Journal of Cell Biology

Citation Impact

Citing Papers

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Self‐organized developmental patterning and differentiation in cerebral organoids
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Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
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Requirement of bic/microRNA-155 for Normal Immune Function
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Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
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Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
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Mouse models of acute and chronic hepacivirus infection
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A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
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Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
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MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex
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2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size
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POU-III Transcription Factors (Brn1, Brn2, and Oct6) Influence Neurogenesis, Molecular Identity, and Migratory Destination of Upper-Layer Cells of the Cerebral Cortex
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Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein
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Functional Maturation of hPSC-Derived Forebrain Interneurons Requires an Extended Timeline and Mimics Human Neural Development
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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
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IgA Response to Symbiotic Bacteria as a Mediator of Gut Homeostasis
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Regulatory T Cells and Immune Tolerance
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Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
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Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
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MicroRNAs: Target Recognition and Regulatory Functions
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Life beyond cleavage: the case of Ago2 and hematopoiesis
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An intrinsic mechanism of corticogenesis from embryonic stem cells
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In vivo reprogramming of adult pancreatic exocrine cells to β-cells
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Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
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Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
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MicroRNAs: new regulators of immune cell development and function
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Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses
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Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
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Foxp3 occupancy and regulation of key target genes during T-cell stimulation
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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
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Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression
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Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
2011
Neural stem and progenitor cells shorten S-phase on commitment to neuron production
2011
The role of senescent cells in ageing
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Cerebral organoids model human brain development and microcephaly
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Novel IgCAM, MDGA1, Expressed in Unique Cortical Area- and Layer-Specific Patterns and Transiently by Distinct Forebrain Populations of Cajal-Retzius Neurons
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Generation of cerebral organoids from human pluripotent stem cells
2014
Organoid single-cell genomic atlas uncovers human-specific features of brain development
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Hepatitis C Virus RNA Functionally Sequesters miR-122
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MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development
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The amyloid hypothesis of Alzheimer's disease at 25 years
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Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
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Nuclear Reprogramming in Cells
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Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing
2011
Regulatory T Cells: Mechanisms of Differentiation and Function
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Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity
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Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
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CD4+CD25LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
2010
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
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Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
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Interactions Between the Microbiota and the Immune System
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The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
2008
Organogenesis in a dish: Modeling development and disease using organoid technologies
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Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
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Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
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How neuroinflammation contributes to neurodegeneration
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Modeling human cortical development in vitro using induced pluripotent stem cells
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Pcid2 Inactivates Developmental Genes in Human and Mouse Embryonic Stem Cells to Sustain Their Pluripotency by Modulation of EID1 Stability
2013
Emerging Challenges in Regulatory T Cell Function and Biology
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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
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Conditional stability of T cells
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Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
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T cell exclusion, immune privilege, and the tumor microenvironment
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Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
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Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
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Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
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The Long-Term Stability of the Human Gut Microbiota
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A distinct subpopulation of CD25T-follicular regulatory cells localizes in the germinal centers
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Differentiation of Effector CD4 T Cell Populations
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Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
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Works of James Smith being referenced

Reversible Block of Mouse Neural Stem Cell Differentiation in the Absence of Dicer and MicroRNAs
2010
APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex Neurons
2015
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
2012
The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis
2009
Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap
2005
A Human Stem Cell Model of Early Alzheimer’s Disease Pathology in Down Syndrome
2012
A role for Dicer in immune regulation
2006 StandoutNobel
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
2010
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2026