Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Antibody Class Switching Mediated by Yeast Endonuclease-Generated DNA Breaks
2006 Science
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development
2008
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
AID from bony fish catalyzes class switch recombination
2005
Programmed Cell Death 1 Suppresses B-1b Cell Expansion and Long-Lived IgG Production in Response to T Cell-Independent Type 2 Antigens
2011
Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory
2007 StandoutNobel
Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair
2007
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
2020 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells
2017 Nature
Glycosylation diseases: Quo vadis?
2008
The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA
2010
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA
2007
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation
2009
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair
2004
Histone Modifications Associated with Somatic Hypermutation
2005
The regulation of immunoglobulin E class-switch recombination
2003
Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
2016 Nature
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
2008
Biological roles of glycans
2016 Standout
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
NHEJ-deficient DT40 cells have increased levels of immunoglobulin gene conversion: evidence for a double strand break intermediate
2006
The development of allergic inflammation
2008 StandoutNature
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists
2011
Regulation of Class-Switch Recombination and Plasma Cell Differentiation by Phosphatidylinositol 3-Kinase Signaling
2006
The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies
2004
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
2021 StandoutNobel
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
2010
Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
2011 StandoutNobel
Membrane lipids: where they are and how they behave
2008 Standout
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
Activation-Induced Cytidine Deaminase Expression in CD4+ T Cells is Associated with a Unique IL-10-Producing Subset that Increases with Age
2011 StandoutNobel
Two distinct but interchangeable mechanisms for flipping of lipid‐linked oligosaccharides
2006
S-S Synapsis during Class Switch Recombination Is Promoted by Distantly Located Transcriptional Elements and Activation-Induced Deaminase
2007
H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations
2006
B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
2009 StandoutNobel
The cellular response to general and programmed DNA double strand breaks
2004
Congenital disorders of glycosylation: review of their molecular bases, clinical presentations and specific therapies
2003
Aid
2004 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc
2004
The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
2010
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
The PI3K Pathway in Human Disease
2017 Standout
In Vivo Analysis of Aicda Gene Regulation: A Critical Balance between Upstream Enhancers and Intronic Silencers Governs Appropriate Expression
2013 StandoutNobel
Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations
2006
Activation-induced deaminase: controversies and open questions
2004
Balancing N-linked glycosylation to avoid disease
2001
Regulation of Immunoglobulin Class-Switch Recombination
2014
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
AID Associates with Single-Stranded DNA with High Affinity and a Long Complex Half-Life in a Sequence-Independent Manner
2006
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
AID Binds Cooperatively with UNG and Msh2-Msh6 to Ig Switch Regions Dependent upon the AID C Terminus
2011
DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
2007
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Fine-Structure Analysis of Activation-Induced Deaminase Accessibility to Class Switch Region R-Loops
2005
Update and perspectives on congenital disorders of glycosylation
2001
Molecular mechanism for generation of antibody memory
2008 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
An Evolutionary View of the Mechanism for Immune and Genome Diversity
2012 StandoutNobel
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
2009 StandoutNobel
Novel Regulators of Bone Formation: Molecular Clones and Activities
1988 StandoutScience
Molecular Mechanisms of Antibody Somatic Hypermutation
2007
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Mechanism and Regulation of Class Switch Recombination
2008
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
APPLICATION OF THE BIOLOGICAL PRINCIPLE OF INDUCED OSTEOGENESIS FOR CRANIOFACIAL DEFECTS
1981
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
2005
AID to overcome the limitations of genomic information
2005 StandoutNobel
Works of James S. Rush being referenced
Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S in Ig class switch recombination
2004
Non‐redundancy of cytidine deaminases in class switch recombination
2004
Mannose supplementation corrects GDP-mannose deficiency in cultured fibroblasts from some patients with Congenital Disorders of Glycosylation (CDG)
2000
Topological studies on the enzymes catalyzing the biosynthesis of Glc-P-dolichol and the triglucosyl cap of Glc3Man9GlcNAc2-P-P-dolichol in microsomal vesicles from pig brain: use of the processing glucosidases I/II as latency markers
1998
The logic of intercellular communication in the immune system
1998
Cross-Linking Surface Ig Delays CD40 Ligand- and IL-4-Induced B Cell Ig Class Switching and Reveals Evidence for Independent Regulation of B Cell Proliferation and Differentiation
2002
OBSERVATIONS ON THE INDUCTION OF BONE IN SOFT TISSUES
1975
Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination
2005