Citation Impact
Citing Papers
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Selective Activation of MEK1 but Not MEK2 by A-Raf from Epidermal Growth Factor-stimulated Hela Cells
1996
Identification of a MAP kinase kinase kinase in phaeochromocytoma (PC12) cells
1992
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1
1998
Cloning and Characterization of a Human STE20-like Protein Kinase with Unusual Cofactor Requirements
1997
Interplay between Cdc2 Kinase and the c-Mos/MAPK Pathway between Metaphase I and Metaphase II in Xenopus Oocytes
2001
MAP kinase by any other name smells just as sweet
1992
Dynamic O-Glycosylation of Nuclear and Cytosolic Proteins
2001
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
A homologue of the MAP/ERK family of protein kinase genes is expressed in vegetative and in female reproductive organs of Petunia hybrida
1995
Extracellular signal-regulated kinases in T cells: Characterization of human ERK1 and ERK2 cDNAs
1992
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation
1996
In VivoRegulation of Cytostatic Activity inXenopusMetaphase II-Arrested Oocytes
1997
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
1994
The mitogen-activated protein kinase activator
1992
Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
1996 Nature
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
1991 Standout
The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo
1993 StandoutNobel
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
1996
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
1992
A novel p34cdc2-binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes
1999
Raf meets Ras: completing the framework of a signal transduction pathway
1994
Mesoderm induction in Xenopus caused by activation of MAP kinase
1995 Nature
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Isolation of two members of the rat MAP kinase kinase gene family
1993
Conservation and reiteration of a kinase cascade
1993
Mitogen‐activated protein kinase (MAP kinase) activation in Xenopus oocytes: Roles of MPF and protein synthesis
1993
Complete Nucleotide Sequence, Expression, and Chromosomal Localisation of Human Mixed‐Lineage Kinase 2
1995
What does mos do in oocytes and somatic cells?
1997
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development
1995
Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins
1995
p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast
1995 StandoutNobel
Diversity in function and regulation of MAP kinase pathways
1994
Activation of p42 Mitogen-activated Protein Kinase in Hippocampal Long Term Potentiation
1996
How MAP Kinases Are Regulated
1995 Standout
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
1994
The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets.
1997
T Cell Proliferation in Response to Interleukins 2 and 7 Requires p38MAP Kinase Activation
1997
Identification of c-Jun NH2-terminal Protein Kinase (JNK)-activating Kinase 2 as an Activator of JNK but Not p38
1997
Isolation and characterization of a tobacco cDNA clone encoding a putative MAP kinase
1993
Mos and the cell cycle: the molecular basis of the transformed phenotype
1993
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways
1994
ERKs, extracellular signal-regulated MAP-2 kinases
1991
MMK2, a novel alfalfa MAP kinase, specifically complements the yeast MPK1 function
1995
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Isolation of a cDNA encoding the rat MAP-kinase homolog of human p63mapk
1996
Ordered phosphorylation of p42mapk by MAP kinase kinase
1992
Mitogen-activated protein kinases: versatile transducers for cell signaling
1992
A tobacco protein kinase, NPK2, has a domain homologous to a domain found in activators of mitogen-activated protein kinases (MAPKKs)
1995
Heterogeneous expression of four MAP kinase isoforms in human tissues
1992
Protein Serine/Threonine Kinases of the MAPK Cascade
1995
Kinase cascade conserved
1992
ATMPKs: a gene family of plant MAP kinases in Arabidopsis thaliana
1993
DNA Topoisomerases: Essential Enzymes and Lethal Targets
1994
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Tumor necrosis factor alpha -induced activation of c-jun N-terminal kinase is mediated by TRAF2
1997
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
Alternative Antigen Receptor (TCR) Signaling in T Cells Derived from ZAP-70-deficient Patients Expressing High Levels of Syk
2000
Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF
1993
Growth factor induced MEK activation is primarily mediated by an activator different from c-raf
1994
A conserved kinase cascade for MAP kinase activation in yeast
1993
Developmental expression in the mouse nervous system of the p493F12 SAP kinase
1996
Molecular cloning and sequencing of a carp cDNA encoding mitogen-activated protein kinase kinase
1994
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
The MAP kinase cascade is essential for diverse signal transduction pathways
1993
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation
1998 StandoutNobel
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
1994 Standout
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor
1999
cAMP-mediated Growth Inhibition in Fibroblasts Is Not Mediated via Mitogen-activated Protein (MAP) Kinase (ERK) Inhibition
1996
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1997
Purification and Characterization of REKS from Xenopus Eggs
1995
Fas- or Ceramide-induced Apoptosis Is Mediated by a Rac1-regulated Activation of Jun N-terminal Kinase/p38 Kinases and GADD153
1997
Cloning of a Novel Mitogen-activated Protein Kinase Kinase Kinase, MEKK4, That Selectively Regulates the c-Jun Amino Terminal Kinase Pathway
1997
Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase
1994 StandoutScience
Isolation of MEK5 and Differential Expression of Alternatively Spliced Forms
1995
hemipterous encodes a novel drosophila MAP kinase kinase, required for epithelial cell sheet movement
1995
Xenopus oocyte maturation: new lessons from a good egg
1999
Speedy: a novel cell cycle regulator of the G2/M transition
1999
Fibroblast Growth Factor-2 Suppression of Tumor Necrosis Factor α-Mediated Apoptosis Requires Ras and the Activation of Mitogen-activated Protein Kinase
1996
The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90Rsk
2000
Advances in Malignant Mesothelioma
2005 Standout
A Novel Regulatory Mechanism in the Mitogen-activated Protein (MAP) Kinase Cascade
1997
cPLA2 is phosphorylated and activated by MAP kinase
1993 Standout
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation
1993
MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase
1993 Science
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
The MAP Kinase Cascade
1995 Nobel
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
1994 StandoutNobel
The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product
1992 Science
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase.
1993
Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.
1994
Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.
1993 Standout
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Mechanisms of Xenopus oocyte maturation
1997
A Role for Mitogen-activated Protein Kinase in the Spindle Assembly Checkpoint in XTC Cells
1997
cDNA cloning of MAP kinase kinase reveals kinase cascade pathways in yeasts to vertebrates.
1993
Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro.
1993
Erks: their fifteen minutes has arrived.
1992
Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate
1993 Science
Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.
1993
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Analysis of the early embryonic cell cycles of Xenopus; regulation of cell cycle length by Xe-wee1 and Mos
1998
Growth factor-induced activation of a kinase activity which causes regulatory phosphorylation of p42/microtubule-associated protein kinase.
1992
MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts
1997
Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade.
1992
Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4
1999
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation.
1994
Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system.
1992
MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts.
1992
Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase.
1992
Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1).
1994
Immunological characterization of avian MAP kinases: evidence for nuclear localization.
1992
Functional Characterization of theMKC1Gene ofCandida albicans, Which Encodes a Mitogen-Activated Protein Kinase Homolog Related to Cell Integrity
1995
Two Distinct Mechanisms Control the Accumulation of Cyclin B1 and Mos inXenopusOocytes in Response to Progesterone
1999
MAP kinase regulation — the oncogene connection
1992
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.
1994
Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis.
1993
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase.
1993
Integrin-mediated cell adhesion activates mitogen-activated protein kinases.
1994
FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.
1993
Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases.
1992
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2
1997
cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells.
1994
Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans
1995
Growth Factor-Induced Activation of a Kinase Activity Which Causes Regulatory Phosphorylation of p42/Microtubule-Associated Protein Kinase
1992
Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse
1996 StandoutNobel
Identification and Functional Analysis of a Developmentally Regulated Extracellular Signal-Regulated Kinase Gene in Dictyostelium discoideum
1994
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs.
1993 StandoutNobel
Regulation of the Cyclin B Degradation System by an Inhibitor of Mitotic Proteolysis
1998
Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf.
1994
Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells.
1994
Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.
1995 StandoutNobel
A chemical approach for identifying O -GlcNAc-modified proteins in cells
2003 StandoutNobel
Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase.
1993
Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse.
1994
Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation
1993
Xenopus MAP kinase activator is a serine/threonine/tyrosine kinase activated by threonine phosphorylation.
1992
Lipopolysaccharide Signals Activation of Tumor Necrosis Factor Biosynthesis Through the Ras/Raf-1/MEK/MAPK Pathway
1994 StandoutNobel
Jun N-Terminal Kinase/Stress-Activated Protein Kinase (JNK/SAPK) Is Required for Lipopolysaccharide Stimulation of Tumor Necrosis Factor Alpha (TNF-α) Translation: Glucocorticoids Inhibit TNF-α Translation by Blocking JNK/SAPK
1997
MAP kinase activator from insulin-stimulated skeletal muscle is a protein threonine/tyrosine kinase.
1992
Biochemical and biological analysis of Mek1 phosphorylation site mutants.
1995
Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.
1994
Activation of protein serine/threonine kinases p42, p63, and p87 in Rous sarcoma virus-transformed cells: signal transduction/transformation-dependent MBP kinases.
1992
PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
1992
Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages.
1995
A Dominant-Negative Mutant of mSOS1 Inhibits Insulin-Induced Ras Activation and Reveals Ras-Dependent and -Independent Insulin Signaling Pathways
1995
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.
1994
Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity.
1994
Activation of p42 MAP kinase and the release of oocytes from cell cycle arrest.
1992
Stimulation of mitogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction.
1992
Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus
1993
Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product.
1992
MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
1995
Membrane Localization of Phosphatidylinositol 3-Kinase Is Sufficient To Activate Multiple Signal-Transducing Kinase Pathways
1996
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
A mitogen-activated protein (MAP) kinase activating factor in mammalian mitogen-stimulated cells is homologous to Xenopus M phase MAP kinase activator.
1992
Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII.
1994 Nobel
How Proteolysis Drives the Cell Cycle
1996 Science
Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator.
1994
Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.
1991
Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells.
1992
Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro
1992 StandoutScience
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts
1993
Raf-1 Protein Kinase Is Important for Progesterone-Induced Xenopus Oocyte Maturation and Acts Downstream of mos
1993
Phosphorylation of Xenopus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase.
1993
MsERK1: a mitogen-activated protein kinase from a flowering plant.
1993
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.
1993
Microtubule and chromatin behavior follow MAP kinase activity but not MPF activity during meiosis in mouse oocytes
1994
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Signal transduction via the MAP kinases: proceed at your own RSK.
1993 Standout
Inhibition by cAMP of Ras-Dependent Activation of Raf
1993 Science
Phorbol ester stimulates a protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product.
1992
Reconstitution of p21ras-dependent and -independent mitogen-activated protein kinase activation in a cell-free system.
1993
A purified S6 kinase kinase from Xenopus eggs activates S6 kinase II and autophosphorylates on serine, threonine, and tyrosine residues.
1992
Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells.
1993
The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells.
1995
Molecular cloning and expression of a MAP kinase homologue from pea
1993
Activation of mitogen-activated protein (MAP) kinase by a MAP kinase-kinase.
1992
Insulin signal transduction through protein kinase cascades
1998
Mitogen-activated protein kinase kinase is required for the mos-induced metaphase arrest.
1994
New B-type cyclin synthesis is required between meiosis I and II duringXenopusoocyte maturation
2001 StandoutNobel
An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase.
1992
A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog.
1994
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.
1993
Similarities between somatic cells overexpressing the mos oncogene and oocytes during meiotic interphase.
1994 StandoutNobel
Cloning and characterization of p97MAPK, a novel human homolog of rat ERK-3.
1994
The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.
1994
Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1.
1993
Stress signaling in plants: a mitogen-activated protein kinase pathway is activated by cold and drought.
1996
Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain.
1996
Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
1993
A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum.
1994
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase
1997
Molecular Cloning and Characterization of a Novel Protein Kinase with a Catalytic Domain Homologous to Mitogen-activated Protein Kinase Kinase Kinase
1996
Cell Cycle Arrest and Reversion of Ras-Induced Transformation by a Conditionally Activated Form of Mitogen-Activated Protein Kinase Kinase Kinase 3
1999
Dissociation of MAP kinase activation and MPF activation in hormone-stimulated maturation of Xenopus oocytes
1999
Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.
1992
The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
1995 StandoutNobel
The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras.
1994
ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation.
1996
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
1994
Extracellular signal-regulated kinases: ERKs in progress.
1991
Signal transduction within the nucleus by mitogen-activated protein kinase.
1992
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Whose end is destruction: cell division and the anaphase-promoting complex
1999
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.
1993
A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium.
1995
Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways.
1993
Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase
1993 Science
Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1.
1995
Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein.
1992
Nuclear localization and regulation of erk- and rsk-encoded protein kinases.
1992
The mitogen-activated protein kinase signal transduction pathway
1993 Standout
Oncogenic ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes.
1992
Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.
1994
Works of James Posada being referenced
p42 mitogen-activated protein kinase in brain: Prominent localization in neuronal cell bodies and dendrites
1993
JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells
1996
The Seven-transmembrane-spanning Receptors for Endothelin and Thrombin Cause Proliferation of Airway Smooth Muscle Cells and Activation of the Extracellular Regulated Kinase and c-Jun NH2-terminal Kinase Groups of Mitogen-activated Protein Kinases
1996
Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts.
1991
Molecular signal integration. Interplay between serine, threonine, and tyrosine phosphorylation.
1992
Tyrosine Phosphorylation and Activation of Homologous Protein Kinases during Oocyte Maturation and Mitogenic Activation of Fibroblasts
1991
Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes
1992 Science
Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells.
1992
Phosphorylation of mitogen-activated protein kinases is involved in the epidermal growth factor and phorbol ester, but not in the thyrotropin/cAMP, thyroid mitogenic pathway.
1993
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro.
1993
Mos Stimulates MAP Kinase in Xenopus Oocytes and Activates a MAP Kinase Kinase In Vitro
1993
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor.
1996
Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells.
1989