Citation Impact
Citing Papers
The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target
2007
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation
2020
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target.
2007
Potent Suppression of HIV Type 1 Infection By a Short Hairpin Anti-CXCR4 siRNA
2003
Anti-idiotypic Antibody to the V3 Domain of gp120 Binds to Vimentin: A Possible Role of Intermediate Filaments in the Early Steps of HIV-1 Infection Cycle
1996
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
Expression, Purification, and Crystallization of the HIV-1 Reverse Transcriptase (RT)
1990
Dynamic personalities of proteins
2007 StandoutNature
Mutagenesis of amino acid residues in the SHV-1 β-lactamase: the premier role of Gly238Ser in penicillin and cephalosporin resistance
2001
Parkinson's disease
2021 Standout
Syntheses of triazole-modified zanamivir analogues via click chemistry and anti-AIV activities
2006
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Protein Structure-Based Drug Design
1994
Substrate requirements of a human rhinoviral 2A proteinase
1991
Structural and biochemical studies of retroviral proteases
2000
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays
1992
Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
2014 StandoutNobel
Altering AAV tropism with mosaic viral capsids
2005
Strategies for containing an emerging influenza pandemic in Southeast Asia
2005 StandoutNature
Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing
2012 StandoutNobel
Intracellular Immunization: Trans -Dominant Mutants of HIV Gene Products as Tools for the Study and Interruption of Viral Replication
1992
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
1996 Standout
The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza viruses
2000
Antiviral chemotherapeutic agents against respiratory viruses
2004
Organic synthesis provides opportunities to transform drug discovery
2018
X-ray Crystallographic Studies of a Series of Penicillin-Derived Asymmetric Inhibitors of HIV-1 Protease
1994
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
Predicting Drug‐Resistant Mutations of HIV Protease
2007 StandoutNobel
Engineering targeted viral vectors for gene therapy
2007
Strategies in the design of antiviral drugs
2002
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
Essential Role of the N-terminal Domain in the Regulation of RIG-I ATPase Activity
2008
Use of the Oral Neuraminidase Inhibitor Oseltamivir in Experimental Human Influenza
1999
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV
2010
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Structure at 2.5-.ANG. resolution of chemically synthesized Human Immunodeficiency Virus Type 1 protease complexed with a hydroxyethylene-based inhibitor
1991
Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2
1999
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Ligand-directed targeting of genes to the site of disease
2003
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
The transmembrane domain in viral fusion: Essential role for a conserved glycine residue in vesicular stomatitis virus G protein
1998
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
Molecular Targets for AIDS Therapy
1990 Science
Sialobiology of Influenza: Molecular Mechanism of Host Range Variation of Influenza Viruses
2005
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Close Is Not Enough
2000 StandoutNobel
Water as an Active Constituent in Cell Biology
2007 Standout
Adeno-Associated Virus Type 2 VP2 Capsid Protein Is Nonessential and Can Tolerate Large Peptide Insertions at Its N Terminus
2004
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
An NMR Perspective on Enzyme Dynamics
2006
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Multiple Mutations in the Human Immunodeficiency Virus Protease Gene Are Responsible for Decreased Susceptibility to Protease Inhibitors
1995
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Synthesis and biological evaluation of a series of HIV-1 protease inhibitors
1993
Constructing Proteins by Dovetailing Unprotected Synthetic Peptides: Backbone-Engineered HIV Protease
1992 Science
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
2003 StandoutNobel
Structure of Complex of Synthetic HIV-1 Protease with a Substrate-Based Inhibitor at 2.3 Å Resolution
1989 Science
Crystal structures of HIV-1 protease-inhibitor complexes
1993
Endogenous reverse transcription of human immunodeficiency virus type 1 in physiological microenviroments: an important stage for viral infection of nondividing cells
1996
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance
1998 StandoutScience
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase
2005
Mechanism for the Noncovalent Chiral Domino Effect: New Paradigm for the Chiral Role of the N-Terminal Segment in a 310-Helix
2003
Structure-Based Strategies for Drug Design and Discovery
1992 Science
Chemoselective Approaches to Glycoprotein Assembly
2001 StandoutNobel
Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors
1996 StandoutNobel
Examining methods for calculations of binding free energies: LRA, LIE, PDLD-LRA, and PDLD/S-LRA calculations of ligands binding to an HIV protease
2000 StandoutNobel
Helical Polymers: Synthesis, Structures, and Functions
2009 Standout
Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.
1996 StandoutNobel
Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors
1994 Science
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Use of a novel human immunodeficiency virus type 1 reporter virus expressing human placental alkaline phosphatase to detect an alternative viral receptor
1995
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
A strategy of exon shuffling for making large peptide repertoires displayed on filamentous bacteriophage.
1996 StandoutNobel
Converting conformational changes to electrostatic energy in molecular motors: The energetics of ATP synthase
2003 StandoutNobel
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
The use of HIV-1 protease structure in inhibitor design
1992
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
1998 Standout
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Synthesis of Proteins by Native Chemical Ligation
1994 StandoutScience
Triple Combination of Oseltamivir, Amantadine, and Ribavirin Displays Synergistic Activity against Multiple Influenza Virus Strains In Vitro
2009
Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase
2001
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of James Merson being referenced
Inhibition of CCR5-Dependent HIV-1 Infection by Hairpin Ribozyme Gene Therapy against CC-Chemokine Receptor 5
2000
Molecular cloning and sequence determination of the fusion protein gene of human parainfluenza virus type 1
1988
Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice
2013
HIV-1 proteinase is required for synthesis of pro-viral DNA
1991
X-ray analysis of HIV-1 proteinase at 2.7 Å resolution confirms structural homology among retroviral enzymes
1989 Nature
Development of Novel Cell Surface CD34-Targeted Recombinant Adenoassociated Virus Vectors for Gene Therapy
1998
Efficacy of GS 4104 in ferrets infected with influenza A virus
1997
Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein.
1999
Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection
1998
Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase
1994
Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071
1998