Standout Papers

Construction of a genetic toggle switch in Escherichia coli 1993 2026 2004 2015 2.9k
  1. Construction of a genetic toggle switch in Escherichia coli (2000)
    Timothy S. Gardner, Charles R. Cantor et al. Nature
  2. Nucleic acid detection with CRISPR-Cas13a/C2c2 (2017)
    Jonathan S. Gootenberg, Omar O. Abudayyeh et al. Science
  3. A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics (2007)
    Michael A. Kohanski, Daniel J. Dwyer et al. Cell
  4. A practical method for calculating largest Lyapunov exponents from small data sets (1993)
    Michael T. Rosenstein, James J. Collins et al. Physica D Nonlinear Phenomena
  5. Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA (2010)
    Luigi Warren, Philip D. Manos et al. Cell stem cell
  6. Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 (2018)
    Jonathan S. Gootenberg, Omar O. Abudayyeh et al. Science
  7. Stochasticity in gene expression: from theories to phenotypes (2005)
    Mads Kærn, Timothy C. Elston et al. Nature Reviews Genetics
  8. How antibiotics kill bacteria: from targets to networks (2010)
    Michael A. Kohanski, Daniel J. Dwyer et al. Nature Reviews Microbiology
  9. Noise in eukaryotic gene expression (2003)
    William J. Blake, Mads Kærn et al. Nature
  10. A Deep Learning Approach to Antibiotic Discovery (2020)
    Jonathan Stokes, Kevin Yang et al. Cell
  11. Highly efficient Cas9-mediated transcriptional programming (2015)
    Alejandro Chavez, Jonathan Scheiman et al. Nature Methods
  12. Wisdom of crowds for robust gene network inference (2012)
    Daniel Marbach, James C. Costello et al. Nature Methods
  13. Large-Scale Mapping and Validation of Escherichia coli Transcriptional Regulation from a Compendium of Expression Profiles (2007)
    Jeremiah J. Faith, Boris Hayete et al. PLoS Biology
  14. Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components (2016)
    Keith Pardee, Alexander A. Green et al. Cell
  15. Synthetic biology: applications come of age (2010)
    Ahmad S. Khalil, James J. Collins Nature Reviews Genetics
  16. Open-loop and closed-loop control of posture: A random-walk analysis of center-of-pressure trajectories (1993)
    James J. Collins, Carlo J. De Luca Experimental Brain Research
  17. Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling (2003)
    Timothy S. Gardner, Diego di Bernardo et al. Science
  18. CRISPR-based diagnostics (2021)
    Michael M. Kaminski, Omar O. Abudayyeh et al. Nature Biomedical Engineering
  19. Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis (2010)
    Michael A. Kohanski, Mark A. DePristo et al. Molecular Cell
  20. Metabolite-enabled eradication of bacterial persisters by aminoglycosides (2011)
    Kyle R. Allison, Mark P. Brynildsen et al. Nature
  21. Cellular Decision Making and Biological Noise: From Microbes to Mammals (2011)
    Gábor Balázsi, Alexander van Oudenaarden et al. Cell
  22. End-to-end design of wearable sensors (2022)
    H. Ceren Ates, Peter Q. Nguyen et al. Nature Reviews Materials
  23. Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip (2015)
    Hyun Jung Kim, Hu Li et al. Proceedings of the National Academy of Sciences
  24. Antibiotics induce redox-related physiological alterations as part of their lethality (2014)
    Daniel J. Dwyer, Peter Belenky et al. Proceedings of the National Academy of Sciences
  25. Dispersing biofilms with engineered enzymatic bacteriophage (2007)
    Timothy K. Lu, James J. Collins Proceedings of the National Academy of Sciences
  26. Stochastic resonance without tuning (1995)
    James J. Collins, Carson C. Chow et al. Nature
  27. Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria (2013)
    José Rubén Morones‐Ramírez, Jonathan Winkler et al. Science Translational Medicine
  28. Toehold Switches: De-Novo-Designed Regulators of Gene Expression (2014)
    Alexander A. Green, Pamela A. Silver et al. Cell
  29. Next-Generation Machine Learning for Biological Networks (2018)
    Diogo M. Camacho, Katherine M. Collins et al. Cell
  30. A brief history of synthetic biology (2014)
    D. Ewen Cameron, Caleb J. Bashor et al. Nature Reviews Microbiology
  31. Antibiotic efficacy is linked to bacterial cellular respiration (2015)
    Michael A. Lobritz, Peter Belenky et al. Proceedings of the National Academy of Sciences
  32. Engineered gene circuits (2002)
    Jeff Hasty, David R. McMillen et al. Nature
  33. Paper-Based Synthetic Gene Networks (2014)
    Keith Pardee, Alexander A. Green et al. Cell
  34. Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses (2018)
    Jang Hwan Cho, James J. Collins et al. Cell
  35. Antibiotics and the gut microbiota (2014)
    James J. Collins, David A. Relman et al. Journal of Clinical Investigation
  36. Syntrophic exchange in synthetic microbial communities (2014)
    Michael T. Mee, James J. Collins et al. Proceedings of the National Academy of Sciences
  37. Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome (2013)
    Henry H. Lee, Catherine S. Spina et al. Nature
  38. Bacterial Metabolism and Antibiotic Efficacy (2019)
    Jonathan Stokes, Allison J. Lopatkin et al. Cell Metabolism
  39. Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage (2015)
    Peter Belenky, Caroline Porter et al. Cell Reports
  40. Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production (2013)
    Mark P. Brynildsen, Jonathan Winkler et al. Nature Biotechnology
  41. Wearable materials with embedded synthetic biology sensors for biomolecule detection (2021)
    Peter Q. Nguyen, Luis R. Soenksen et al. Nature Biotechnology
  42. Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants (2021)
    Helena de Puig, Rose Lee et al. Science Advances
  43. Clinically relevant mutations in core metabolic genes confer antibiotic resistance (2021)
    Allison J. Lopatkin, Abigail L. Manson et al. Science
  44. Engineering living therapeutics with synthetic biology (2021)
    Andrés Cubillos-Ruiz, Tingxi Guo et al. Nature Reviews Drug Discovery
  45. A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma (2022)
    Devora Najjar, Joshua Rainbow et al. Nature Biomedical Engineering
  46. Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii (2023)
    Gary Liu, Denise B. Catacutan et al. Nature Chemical Biology
  47. Nanozyme-catalysed CRISPR assay for preamplification-free detection of non-coding RNAs (2022)
    Marta Broto, Michael M. Kaminski et al. Nature Nanotechnology
  48. Benchmarking AlphaFold ‐enabled molecular docking predictions for antibiotic discovery (2022)
    Felix Wong, Aarti Krishnan et al. Molecular Systems Biology
  49. Leveraging artificial intelligence in the fight against infectious diseases (2023)
    Felix Wong, César de la Fuente‐Núñez et al. Science
  50. Machine learning for antimicrobial peptide identification and design (2024)
    Fangping Wan, Felix Wong et al. Nature Reviews Bioengineering

Immediate Impact

17 by Nobel laureates 66 from Science/Nature 98 standout
Sub-graph 1 of 12

Citing Papers

CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
35 intermediate papers

Works of James J. Collins being referenced

Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
2018 Standout
Synthetic biology devices for in vitro and in vivo diagnostics
2015
and 20 more

Author Peers

Author Last Decade Papers Cites
James J. Collins 44644 10046 5360 11942 327 71.9k
Yoav Benjamini 29933 12221 264 1923 139 97.8k
Yosef Hochberg 26016 10702 226 1709 64 86.6k
Ronald W. Davis 55358 13127 66 10075 539 82.7k
M Snyder 57345 10746 130 3891 884 79.8k
Klaus Schulten 62362 4263 1866 14646 510 115.8k
Charles R. Cantor 22831 5489 480 2519 330 32.5k
Uri Alon 21388 5991 3328 1405 217 31.1k
Rakesh K. Jain 56025 3584 117 36683 849 131.8k
Joseph Wang 24316 449 537 54654 1.1k 104.5k
Peer Bork 93864 14899 417 2769 510 140.1k

All Works

Loading papers...

Rankless by CCL
2026