Citation Impact
Citing Papers
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
1993
Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros
1999
Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
1995
Cloning and Characterization of a Novel Matrix Metalloproteinase (MMP), CMMP, from Chicken Embryo Fibroblasts
1998
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
Telomeres: No end in sight
1994 StandoutNobel
The epigenetic regulation of mammalian telomeres
2007
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T
1990
A dominant negative mutant of jun blocking 12-O-tetradecanoylphorbol-13-acetate–induced invasion in mouse keratinocytes
1997
The language of covalent histone modifications
2000 StandoutNature
Telomere states and cell fates
2000 StandoutNatureNobel
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Development and Disease in Proteinase-Deficient Mice
1998
When Checkpoints Fail
1997 StandoutNobel
Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
1995 StandoutNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Functional Characterization and Developmental Regulation of Mouse Telomerase RNA
1995 StandoutScienceNobel
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Progressive cis-inhibition of telomerase upon telomere elongation
1999
Crystal structure of the nucleosome core particle at 2.8 Å resolution
1997 StandoutNature
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
Position effect variegation at fission yeast centromeres
1994
Neurotrophin signal transduction in the nervous system
2000 Standout
The roles of telomeres and telomerase in cell life span
1996
Putting tumours in context
2001 Standout
COMMENTARY: p53 Tumor suppressor gene: from the basic research laboratory to the clinic—an abridged historical perspective
1996
Telomeres Do D-Loop–T-Loop
1999 StandoutNobel
Shp‐2 Specifically Regulates Several Tyrosine‐Phosphorylated Proteins in Brain‐Derived Neurotrophic Factor Signal
2000
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
Expression of Autoactivated Stromelysin-1 in Mammary Glands of Transgenic Mice Leads to a Reactive Stroma During Early Development
1998
Chemical remodelling of cell surfaces in living animals
2004 StandoutNatureNobel
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
Matrix metalloproteinases: effectors of development and normal physiology
2000
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
2000
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Mouse p53 inhibits SV40 origin-dependent DNA replication
1987 Nature
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor TrkA
1999
Shp‐2 positively regulates brain‐derived neurotrophic factor‐promoted survival of cultured ventral mesencephalic dopaminergic neurons through a brain immunoglobulin‐like molecule with tyrosine‐based activation motifs/Shp substrate‐1
2002
Timp-1 Is Important for Epithelial Proliferation and Branching Morphogenesis during Mouse Mammary Development
1999
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination
1998 StandoutNatureNobel
Telomerase-Independent Lengthening of Yeast Telomeres Occurs by an Abrupt Rad50p-Dependent, Rif-Inhibited Recombinational Process
2000
The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis
1999
The Hallmarks of Aging
2013 Standout
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family
1997
Two types of telomeric chromatin in Tetrahymena thermophila 1 1Edited by T. Richmond
1998
The Telobox, a Myb-Related Telomeric DNA Binding Motif Found in Proteins from Yeast, Plants and Human
1996
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
A novel mechanism for telomere size control in Saccharomyces cerevisiae.
1996
Tetrahymena proteins p80 and p95 are not core telomerase components
2001 StandoutNobel
An Essential Yeast Gene Encoding a TTAGGG Repeat-Binding Protein
1993
TLC1 : Template RNA Component of Saccharomyces cerevisiae Telomerase
1994 Science
Rap1 protein regulates telomere turnover in yeast
1998 StandoutNobel
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Simian virus 40 origin auxiliary sequences weakly facilitate T-antigen binding but strongly facilitate DNA unwinding.
1990 StandoutNobel
Telomerase activity, cell proliferation, and cancer
1998 StandoutNobel
Telomere Folding Is Required for the Stable Maintenance of Telomere Position Effects in Yeast
2000
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Hir Proteins Are Required for Position-Dependent Gene Silencing in Saccharomyces cerevisiae in the Absence of Chromatin Assembly Factor I
1998
The rate of telomere sequence loss in human leukocytes varies with age
1998 StandoutNobel
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins.
1993
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.
1997
SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.
1997
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
The Saccharomyces CDC 13 protein is a single-strand TG 1–3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
1996
Human DNA-Activated Protein Kinase Phosphorylates Serines 15 and 37 in the Amino-Terminal Transactivation Domain of Human p53
1992
Telomere fusions caused by mutating the terminal region of telomeric DNA
2000 StandoutNobel
A Protein-Counting Mechanism for Telomere Length Regulation in Yeast
1997 Science
Telomerase in Yeast
1995 StandoutScienceNobel
Telomere-associated chromosome breakage in fission yeast results in variegated expression of adjacent genes.
1994
Activation of a yeast replication origin near a double-stranded DNA break.
1994
Translating the Histone Code
2001 StandoutScience
Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage.
1993
The Yeast Telomere Length Counting Machinery Is Sensitive to Sequences at the Telomere-Nontelomere Junction
1999
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
C-Terminal Truncation of RAP1 Results in the Deregulation of Telomere Size, Stability, and Function in Saccharomyces cerevisiae
1992
An essential yeast gene encoding a TTAGGG repeat-binding protein.
1993
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1
1999
Telomeres: Beginning to Understand the End
1995 Science
Comparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domains
1997
STRUCTURE, FUNCTION, AND REPLICATION OF SACCHAROMYCES CEREVISIAE TELOMERES
1996
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
1999 StandoutNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing.
1995
Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer
2006
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
1997 StandoutNobel
Works of James H. Wright being referenced
Saccharomyces telomeres assume a non-nucleosomal chromatin structure.
1992
Properties of a simian virus 40 mutant T antigen substituted in the hydrophobic region: defective ATPase and oligomerization activities and altered phosphorylation accompany an inability to complex with cellular p53
1989
Free and viral chromosome-bound simian virus 40 T antigen: changes in reactivity of specific antigenic determinants during lytic infection
1986
Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development.
1995
A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation.
1997
Altered phosphorylation of free and bound forms of monkey p53 and simian virus 40 large T antigen during lytic infection
1992