Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension
2010
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
2010 StandoutScience
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation
2008
Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1α in Long-Lived Mclk1 +/− Mouse Mutants
2009
Mitochondrial reactive oxygen species regulate hypoxic signaling
2009
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Mitochondrial function provides instructive signals for activation-induced B-cell fates
2015
The role of nuclear lamin B1 in cell proliferation and senescence
2011
Chromosome translocations: dangerous liaisons revisited
2001
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
2009 StandoutNature
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
2008
Signaling the mitochondrial unfolded protein response
2012
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
2008 Standout
Pattern Recognition Receptors and Inflammation
2010 Standout
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio
2009
Neonatal Intermittent Hypoxia Leads to Long-Lasting Facilitation of Acute Hypoxia-Evoked Catecholamine Secretion From Rat Chromaffin Cells
2009
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Mitochondrial pharmacology
2012
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels
2011
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Taking a “good” look at free radicals in the aging process
2011
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Mitochondria-targeted Antioxidants Protect Pancreatic β-cells against Oxidative Stress and Improve Insulin Secretion in Glucotoxicity and Glucolipotoxicity
2011
T cell Activation Is Driven by an ADP-Dependent Glucokinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation
2012
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis
2015
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
Physiological Roles of Mitochondrial Reactive Oxygen Species
2012 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling
2013
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/–/ApoE–/– mice
2011
MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
2014
Mitochondria as Oxidative Signaling Organelles in T-cell Activation: Physiological Role and Pathological Implications
2013
Metabolic Regulation of Redox Status in Stem Cells
2014
Clues from cell metabolism
2010 StandoutNatureNobel
Mitochondrial redox signalling at a glance
2012
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Hypoxia-inducible Factor-1α Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion
2007
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
Mitochondria and cellular oxygen sensing in the HIF pathway
2007
The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity
2012 StandoutNobel
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
How mitochondria produce reactive oxygen species
2008 Standout
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species
2010
Signal transduction by reactive oxygen species
2011 Standout
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Uncoupling proteins and the control of mitochondrial reactive oxygen species production
2011
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
2009
Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
2013
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
2013
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Cells Lacking Rieske Iron-Sulfur Protein Have a Reactive Oxygen Species-Associated Decrease in Respiratory Complexes I and IV
2011
Hypoxia. 2. Hypoxia regulates cellular metabolism
2010
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Loss of the SdhB, but Not the SdhA, Subunit of Complex II Triggers Reactive Oxygen Species-Dependent Hypoxia-Inducible Factor Activation and Tumorigenesis
2007
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation
2011
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription
2012
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
2010
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of James Eisenbart being referenced
Mitochondrial Complex III ROS Regulate Adipocyte Differentiation
2011
Epithelial Cell Death Is an Important Contributor to Oxidant-mediated Acute Lung Injury
2010
Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1–1.5 Mb and preparation of a PAC-based physical map
1997
Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.
1996
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
2007
Mitochondrial Reactive Oxygen Species Trigger Hypoxia-Inducible Factor-Dependent Extension of the Replicative Life Span during Hypoxia
2007