Citation Impact
Citing Papers
Transforming Growth Factor-β Signaling–Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion
2008
Ly6c+ “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis
2008
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates
2016
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
2004 StandoutNobel
Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability
2009
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
Persistent endothelial abnormalities and blood–brain barrier leak in primary and secondary progressive multiple sclerosis
2007
Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy
2004
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
2005 Standout
Targeting death-inducing receptors in cancer therapy
2007
Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
2006
Coinfection With HIV-1 and HCV—A One-Two Punch
2009
From bench to clinic with apoptosis-based therapeutic agents
2000 Nature
c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention
2004
Structure and function of the blood–brain barrier
2009 Standout
Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes
2003
Occludin is overexpressed in Alzheimer's disease and vascular dementia
2007
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
2001
Cancer Metastasis: Building a Framework
2006 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
Molecular Cross-talk between the TRAIL and Interferon Signaling Pathways
2002
INDUCTION AND INHIBITION OF CYTOCHROMES P450 BY THE ST. JOHN’S WORT CONSTITUENT HYPERFORIN IN HUMAN HEPATOCYTE CULTURES
2004
Organoid Models and Applications in Biomedical Research
2015 Standout
Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL
2001
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Survival and apoptosis: a dysregulated balance in liver cancer
2007
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
2001
Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
2007
No Association Between Hepatitis C and B–Cell Lymphoma
1999
Diabetic Retinopathy
2012 Standout
Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
2002
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Death receptors in chemotherapy and cancer
2004
The microenvironment of the tumour–host interface
2001 StandoutNature
Effects of Bergamottin on Human and Monkey Drug-Metabolizing Enzymes in Primary Cultured Hepatocytes
2002
Liver regeneration
2007
Apo2L/TRAIL and its death and decoy receptors
2003
The polycomb group protein EZH2 is involved in progression of prostate cancer
2002 StandoutNature
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
2004
Apoptosis
2002 Standout
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
Limited role of COX-2 in HIV Tat-induced alterations of tight junction protein expression and disruption of the blood–brain barrier
2007
Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier
2003
Host defense, viruses and apoptosis
2001
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
2001
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
The basics of epithelial-mesenchymal transition
2009 Standout
An Inducible Pathway for Degradation of FLIP Protein Sensitizes Tumor Cells to TRAIL-induced Apoptosis
2002
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood–brain barrier leakage and active demyelination
2003
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
BI-1 Regulates an Apoptosis Pathway Linked to Endoplasmic Reticulum Stress
2004 StandoutNobel
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
Liver Regeneration after Partial Hepatectomy
2009
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Pericytes regulate the blood–brain barrier
2010 StandoutNature
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier
2003
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release
2001
Inhibition of Hepatobiliary Transport as a Predictive Method for Clinical Hepatotoxicity of Nefazodone
2006
Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines
2001
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
2002
Artificial human Met agonists based on macrocycle scaffolds
2015
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Alternative activation of macrophages
2003 Standout
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
2011 StandoutNature
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
Review: Molecular pathogenesis of blood–brain barrier breakdown in acute brain injury
2010
Towards novel paradigms for cancer therapy
2010
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness
2002
Molecular Pathways: Sensitivity and Resistance to Anti-EGFR Antibodies
2015
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling
2001
An optimal culture condition maintains human hepatocyte phenotype after long-term culture.
2006
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Signaling Mechanisms of HIV-1 Tat-Induced Alterations of Claudin-5 Expression in Brain Endothelial Cells
2005
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
The Met pathway: master switch and drug target in cancer progression
2006
Polycyclic Polyprenylated Acylphloroglucinols
2006 Standout
CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors
2018
HIV-1 gp120 Compromises Blood–Brain Barrier Integrity and Enhance Monocyte Migration across Blood–Brain Barrier: Implication for Viral Neuropathogenesis
2006
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
TRAIL-coated leukocytes that kill cancer cells in the circulation
2014
Involvement of TRAIL and its receptors in viral hepatitis
2002
Isotype-Dependent Inhibition of Tumor Growth In Vivo by Monoclonal Antibodies to Death Receptor 4
2001
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
2005 Standout
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Accumulation of B Lymphocytes with a Naive, Resting Phenotype in a Subset of Hepatitis C Patients
2003 StandoutNobel
Inhibition of HIV-1 Infection by Small Interfering RNA-Mediated RNA Interference
2002 StandoutNobel
St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
2000
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of James E. Esplen being referenced
Troglitazone Increases Cytochrome P-450 3A Protein and Activity in Primary Cultures of Human Hepatocytes
1999
Cross-talk between Epidermal Growth Factor Receptor and c-Met Signal Pathways in Transformed Cells
2000
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
2000
Blood-Brain Barrier Tight Junction Disruption in Human Immunodeficiency Virus-1 Encephalitis
1999
The Use of Human Hepatocyte Cultures to Study the Induction of Cytochrome P-450
1999