Standout Papers

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia 2009 2026 2014 2020 1.4k
  1. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (2011)
    Johannes Zuber, Junwei Shi et al. Nature
  2. HDAC2 negatively regulates memory formation and synaptic plasticity (2009)
    Ji‐Song Guan, Stephen J. Haggarty et al. Nature
  3. Phthalimide conjugation as a strategy for in vivo target protein degradation (2015)
    Georg E. Winter, Dennis L. Buckley et al. Science
  4. Transcriptional Amplification in Tumor Cells with Elevated c-Myc (2012)
    Charles Y. Lin, Jakob Lovén et al. Cell
  5. The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins (2013)
    Gang Lu, Richard E. Middleton et al. Science
  6. Transcriptional Addiction in Cancer (2017)
    James E. Bradner, Denes Hnisz et al. Cell
  7. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies (2007)
    Jayne M. Stommel, Alec C. Kimmelman et al. Science
  8. YY1 Is a Structural Regulator of Enhancer-Promoter Loops (2017)
    Abraham S. Weintraub, Charles H. Li et al. Cell
  9. The dTAG system for immediate and target-specific protein degradation (2018)
    Behnam Nabet, Justin M. Roberts et al. Nature Chemical Biology
  10. Direct inhibition of the NOTCH transcription factor complex (2009)
    Raymond E. Moellering, Melanie Cornejo et al. Nature
  11. PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib (2007)
    Jeffrey A. Engelman, Kreshnik Zejnullahu et al. Cancer Research
  12. Chemical phylogenetics of histone deacetylases (2010)
    James E. Bradner, Nathan West et al. Nature Chemical Biology
  13. Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma (2013)
    Bjoern Chapuy, Michael R. McKeown et al. Cancer Cell
  14. Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition (2013)
    Alexandre Puissant, Stacey M. Frumm et al. Cancer Discovery
  15. Plasticity in binding confers selectivity in ligand-induced protein degradation (2018)
    Radosław P. Nowak, Stephen L. DeAngelo et al. Nature Chemical Biology
  16. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation (2017)
    Heike Brötz‐Oesterhelt, Baishan Jiang et al. Nature Chemical Biology
  17. A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader (2017)
    Hai‐Tsang Huang, Joshiawa Paulk et al. Cell chemical biology

Immediate Impact

3 by Nobel laureates 39 from Science/Nature 88 standout
Sub-graph 1 of 19

Citing Papers

SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys
2024 StandoutScience
H3K4me3 regulates RNA polymerase II promoter-proximal pause-release
2023 StandoutNature
44 intermediate papers

Works of James E. Bradner being referenced

The dTAG system for immediate and target-specific protein degradation
2018 Standout
Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions
2015
and 37 more

Author Peers

Author Last Decade Papers Cites
James E. Bradner 23568 5769 6181 217 28.2k
Andrew L. Kung 16386 4058 6498 282 23.8k
Victoria M. Richon 20102 2623 5158 122 22.7k
Craig M. Crews 26797 5448 10923 206 30.8k
Ricky W. Johnstone 18402 1960 7643 244 24.9k
Paul A. Marks 17540 2038 4521 201 22.0k
E. Premkumar Reddy 10327 1437 4752 203 17.0k
A. Ullrich 22416 1486 8998 192 32.8k
Hong Wu 16440 2612 7083 203 25.8k
Nathanael S. Gray 29806 3346 10733 471 41.2k
Kevan M. Shokat 23898 1067 6774 301 33.5k

All Works

Loading papers...

Rankless by CCL
2026