Standout Papers
- Intracellular Carbon Fluxes in Riboflavin-Producing Bacillus subtilis during Growth on Two-Carbon Substrate Mixtures (2002)
- Detecting and dissecting metabolic fluxes using biosynthetic fractional 13C labeling and two-dimensional NMR spectroscopy (1996)
- Metabolic Flux Ratio Analysis of Genetic and Environmental Modulations of Escherichia coli Central Carbon Metabolism (1999)
- Metabolic fluxes in riboflavin-producing Bacillus subtilis (1997)
- Metabolic Flux Responses to Pyruvate Kinase Knockout in Escherichia coli (2002)
- Bioreaction Network Topology and Metabolic Flux Ratio Analysis by Biosynthetic Fractional 13C Labeling and Two-Dimensional NMR Spectroscopy (1999)
- 13C NMR Flux Ratio Analysis of Escherichia coli Central Carbon Metabolism in Microaerobic Bioprocesses (1999)
- Dissection of Central Carbon Metabolism of Hemoglobin-Expressing Escherichia coli by 13 C Nuclear Magnetic Resonance Flux Distribution Analysis in Microaerobic Bioprocesses (2001)
Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae
2012 StandoutScienceNobel
Directed evolution of a genetic circuit
2002 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat
2005 StandoutScienceNobel
Shewanella secretes flavins that mediate extracellular electron transfer
2008 Standout
Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference
2015
Computational studies of gene regulatory networks: in numero molecular biology
2001
Chapter 8 Use of Recombinant Adenovirus for Metabolic Engineering of Mammalian Cells
1994
Deuterium isotope effects on the central carbon metabolism of Escherichia coli cells grown on a D2O-containing minimal medium
2000 StandoutNobel
Programmable single-cell mammalian biocomputers
2012 Nature
Mutations in ARS1 increase the rate of simple loss of plasmids in Saccharomyces cerevisiae
1986
Advances in Escherichia coli production of therapeutic proteins
2001
Network biology: understanding the cell's functional organization
2004 Standout
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Getting the glycosylation right: Implications for the biotechnology industry
1996
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Synthetic metabolism: metabolic engineering meets enzyme design
2017
An alternative pathway for yeast telomere maintenance rescues est1− senescence
1993 StandoutNobel
A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation
1987
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs
2001
The roles of the eukaryotic DNA polymerases in DNA repair synthesis
1997
Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian Cells
2016
Nucleosome positioning can affect the function of a cis-acting DMA elementin vivo
1990 Nature
p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast
1995 StandoutNobel
Global organization of metabolic fluxes in the bacterium Escherichia coli
2004 Nature
Gene Ontology: tool for the unification of biology
2000 Standout
CCR4 as a novel molecular target for immunotherapy of cancer
2006
Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication
1987
Identification of two factors which bind to the upstream sequences of a number of nuclear genes coding for mitochondrial proteins and to genetic elements important for cell division in yeast
1988
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Natural Killer Cell Mediated Antibody-Dependent Cellular Cytotoxicity in Tumor Immunotherapy with Therapeutic Antibodies
2013
Cap-dependent and cap-independent translation in eukaryotic systems
2004
In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
2001
Two steps in the assembly of complexes at yeast replication origins in vivo
1994
Engineering explored
2014 StandoutNatureNobel
Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes
2012
Metabolic Fluxes during Strong Carbon Catabolite Repression by Malate in Bacillus subtilis
2009
Improving lycopene production in Escherichia coli by engineering metabolic control
2000
An engineered epigenetic transgene switch in mammalian cells
2004
Cryo-EM Visualization of a Viral Internal Ribosome Entry Site Bound to Human Ribosomes
2004 StandoutNobel
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
The fission yeast cdc18+ gene product couples S phase to START and mitosis
1993 StandoutNobel
Determination of Nucleotides and Sugar Nucleotides Involved in Protein Glycosylation by High-Performance Anion-Exchange Chromatography: Sugar Nucleotide Contents in Cultured Insect Cells and Mammalian Cells
2001
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Modeling biological systems using Dynetica—a simulator of dynamic networks
2003
The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone
1988 StandoutNobel
Optimisation of protein expression and establishment of the Wave Bioreactor for Baculovirus/insect cell culture
2002
A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
1990 StandoutNobel
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
1990 StandoutNatureNobel
DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene
1989
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Irresistible force meets immovable object: Transcription and the nucleosome
1991 StandoutNobel
Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth
2002 Nature
Computational systems biology
2002 Nature
Hypoxic Induction of the Human Erythropoietin Gene: Cooperation between the Promoter and Enhancer, Each of Which Contains Steroid Receptor Response Elements
1992
Purification and characterization of proteins that bind to yeast ARSs.
1988
Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles
2001 StandoutNobel
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Naturally Occurring Dicistronic Cricket Paralysis Virus RNA Is Regulated by Two Internal Ribosome Entry Sites
2000
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Replication and Segregation of Plasmids Containing cis-Acting Regulatory Sites of Silent Mating-Type Genes in Saccharomyces cerevisiae Are Controlled by the SIR Genes
1987
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Metabolic Engineering: Past and Future
2013
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
1997 StandoutNobel
Challenges in Engineering Microbes for Biofuels Production
2007 Science
Fine-Structure Analysis of the DNA Sequence Requirements for Autonomous Replication of Saccharomyces cerevisiae Plasmids
1986
Chemical Glycobiology
2001 StandoutScienceNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Manufacturing Molecules Through Metabolic Engineering
2010 Science
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
Impact of host cell line choice on glycan profile
2017
Transcription Interferes with Elements Important for Chromosome Maintenance in Saccharomyces cerevisiae
1988
Bent DNA at a yeast autonomously replicating sequence
1986 Nature
Amino Acid Biosynthesis in the Halophilic Archaeon Haloarcula hispanica
1999 StandoutNobel
Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids.
1986
MCM Proteins in DNA Replication
1999
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.
1988 StandoutNobel
S Phase of the Cell Cycle
1989 Science
Cellular checkpoint control using programmable sequential logic
2018 Science
A possible role for the yeast TATA-element-binding protein in DNA replication.
1993
Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae
1988 StandoutNobel
A genetic analysis of dicentric minichromosomes in saccharomyces cerevisiae
1987 StandoutNobel
Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae.
1988
The Saccharomyces cerevisiae chromosome III left telomere has a type X, but not a type Y', ARS region.
1986
A yeast ARS-binding protein activates transcription synergistically in combination with other weak activating factors.
1990 StandoutNobel
New Directions in Glycoprotein Engineering
2000 StandoutNobel
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.
1994 StandoutNobel
Analysis of optimality in natural and perturbed metabolic networks
2002
Molecular breeding: The natural approach to protein design
2001
Yeast chromosome replication and segregation
1988
Chromosome length controls mitotic chromosome segregation in yeast
1986 StandoutNobel
Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.
1988 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Enzyme Redesign
2001
A group of interacting yeast DNA replication genes.
1991
The Structure of Sister Minichromosome DNA Before Anaphase in Saccharomyces Cerevisiae
1987 StandoutScienceNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer.
1988
Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements.
1992
Programmable bacteria detect and record an environmental signal in the mammalian gut
2014
Genetic analysis of the mitotic transmission of minichromosomes
1985
Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.
1992
Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction Using a Molecular Motor
2011 StandoutScienceNobel
Structure and function of telomeres
1991 StandoutNatureNobel
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
Detection of bacterial ?-galactosidase activity in individual Saccharomyces cerevisiae cells by flow cytometry
1983
De novo design of protein logic gates
2020 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Works of James E. Bailey being referenced
Mathematical modeling of a single‐cell enzyme assay
1990
Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli
1988 Nature
Modeling the population dynamics of baculovirus‐infected insect cells: Optimizing infection strategies for enhanced recombinant protein yields
1992
Propagation of an amplifiable recombinant plasmid in Saccharomyces cerevisiae: flow cytometry studies and segregated modeling
1990
Insect Cell Hosts for Baculovirus Expression Vectors Contain Endogenous Exoglycosidase Activity
1993
Reflections on the Scope and the Future of Metabolic Engineering and Its Connections to Functional Genomics and Drug Discovery
2001
Expression of Intracellular Hemoglobin Improves Protein Synthesis in Oxygen-Limited Escherichia coli
1990
Communication to the editor. Application of the cross‐regulation system as a metabolic switch
1994
Metabolic fluxes in riboflavin-producing Bacillus subtilis
1997 StandoutNobel
Polycistronic gene expression in yeast versus cryptic promoter elements
2002
Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis
2001
Factors influencing recombinant protein yields in an insect cell–bacuiovirus expression system: Multiplicity of infection and intracellular protein degradation
1991
Synthesis of Bisected Glycoforms of Recombinant IFN‐β by Overexpression of β‐1,4‐N‐Acetylglucosaminyltransferase III in Chinese Hamster Ovary Cells
1998
Central carbon metabolism of Saccharomyces cerevisiae explored by biosynthetic fractional 13C labeling of common amino acids
2001
Tissue Plasminogen Activator Coexpressed in Chinese Hamster Ovary Cells with α(2,6)‐Sialyltransferase Contains NeuAcα(2,6)Galβ(1,4)Gl‐N‐AcR Linkages
1995
Complex biology with no parameters
2001
Macrolide-based transgene control in mammalian cells and mice
2002
Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity
1999
pTRIDENT, a novel vector family for tricistronic gene expression in mammalian cells
1998
Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes
2002
Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells
1998
Bioreaction Network Topology and Metabolic Flux Ratio Analysis by Biosynthetic Fractional 13C Labeling and Two-Dimensional NMR Spectroscopy
1999 StandoutNobel
Plasmid presence changes the relative levels of many host cell proteins and ribosome components in recombinant Escherichia coli
1991
Deletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae.
1984
Metabolic Flux Responses to Pyruvate Kinase Knockout in Escherichia coli
2002 StandoutNobel
Use of a glycerol-limited, long-term chemostat for isolation of Escherichia coli mutants with improved physiological properties
1997
Deletion Mutations Affecting Autonomously Replicating Sequence ARS1 of Saccharomyces cerevisiae
1984
Metabolic Flux Ratio Analysis of Genetic and Environmental Modulations of Escherichia coli Central Carbon Metabolism
1999 StandoutNobel
Effect of ARS1 mutations on chromosome stability in Saccharomyces cerevisiae.
1985
13C NMR Flux Ratio Analysis of Escherichia coli Central Carbon Metabolism in Microaerobic Bioprocesses
1999 StandoutNobel
Detecting and dissecting metabolic fluxes using biosynthetic fractional 13C labeling and two-dimensional NMR spectroscopy
1996 StandoutNobel
Effect of ARS1 Mutations on Chromosome Stability in Saccharomyces cerevisiae
1985
Intracellular Carbon Fluxes in Riboflavin-Producing Bacillus subtilis during Growth on Two-Carbon Substrate Mixtures
2002 StandoutNobel
Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes
1996
DNA polymerase I is required for premeiotic DNA replication and sporulation but not for X-ray repair in Saccharomyces cerevisiae.
1989
Construction and characterization of a novel cross-regulation system for regulating cloned gene expression in Escherichia coli
1993
Flow microfluorometry measurements of multicomponent cell composition during batch bacterial growth
1980
Toward a Science of Metabolic Engineering
1991 Science