Citation Impact
Citing Papers
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Multiple myeloma
2014
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Regulation of p53 stability by Mdm2
1997 StandoutNature
The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol
1996 Standout
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
A viral inhibitor of peptide transporters for antigen presentation
1995 Nature
Genomics, gene expression and DNA arrays
2000 Nature
Selectivity of MHC-encoded peptide transporters from human, mouse and rat
1994 Nature
The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70
1997 StandoutNobel
Viral Chemokine Receptors and Chemokines in Human Cytomegalovirus Trafficking and Interaction with the Immune System
2002
Signaling Pathways Leading to Transcription and Translation Cooperatively Regulate the Transient Increase in Expression of c-Fos Protein
2001 StandoutNobel
Proteasome- and p53-dependent Masking of Signal Transducer and Activator of Transcription (STAT) Factors
1997 StandoutNobel
Down-regulation of the MHC class I antigen-processing machinery after oncogenic transformation of murine fibroblasts
1998
Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules
1992 Nature
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
2006 StandoutNobel
Progranulin in the hematopoietic compartment protects mice from atherosclerosis
2018
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
Phytochromes and light signal perception by plants—an emerging synthesis
2000 StandoutNature
Constitutive and interferon-γ-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 11EMBL accession number for MECL1 cDNA: Y13640.1
1998
Identification of genes expressed in C. elegans touch receptor neurons
2002 StandoutNatureNobel
Incorporation of major histocompatibility complex – encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon‐γ
1995
Degradation of 3-Hydroxy-3-methylglutaryl-CoA Reductase in Endoplasmic Reticulum Membranes Is Accelerated as a Result of Increased Susceptibility to Proteolysis
1996 StandoutNobel
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
In Vivo Assembly of the Proteasomal Complexes, Implications for Antigen Processing
1995
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
1996 StandoutNature
Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency
2017
20 S proteasomes are assembled via distinct precursor complexes processing of LMP2 and LMP7 proproteins takes place in 13–16 S preproteasome complexes
1994
Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport
1995
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Degradation Process of Ligand-stimulated Platelet-derived Growth Factor β -Receptor Involves Ubiquitin-Proteasome Proteolytic Pathway
1995 StandoutNobel
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
1998 StandoutNature
Interferon Regulatory Factor 1 Mediates the Interferon-γ Induction of the Human Immunoproteasome Subunit Multicatalytic Endopeptidase Complex-like 1
1999
Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
1998
Structure of 20S proteasome from yeast at 2.4Å resolution
1997 StandoutNatureNobel
The Amyloid State of Proteins in Human Diseases
2012 Standout
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1994 Standout
Protein complexes in snake venom
2009
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
2000 StandoutNature
Degradation of CFTR by the ubiquitin-proteasome pathway
1995 Standout
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
2008
Retinopathy induced in mice by targeted disruption of the rhodopsin gene
1997 StandoutNobel
The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
1994 Standout
Atherosclerosis
2001 Standout
20S proteasome from LMP7 knock out mice reveals altered proteolytic activities and cleavage site preferences
1996
Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity
1996 StandoutNobel
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Frailty in elderly people
2013 Standout
Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin
1995 ScienceNobel
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Retinitis pigmentosa
1988
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
Two Families of GTPases Dominate the Complex Cellular Response to IFN-γ
1998
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.
1994
Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.
1996 Nobel
Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells
1998 StandoutScience
Potential Immunocompetence of Proteolytic Fragments Produced by Proteasomes before Evolution of the Vertebrate Immune System
1997 StandoutNobel
Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes.
1996
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.
1996 StandoutNobel
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90)
1994 Science
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays
2009
A comprehensive two-hybrid analysis to explore the yeast protein interactome
2001 Standout
Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-dependent Removal from ER Membranes
1998 StandoutNobel
Proteasomes in the archaea: from structure to function
2000
Two families of GTPases dominate the complex cellular response to IFN-gamma.
1998
Identification by Large-Scale Screening of Phytochrome-Regulated Genes in Etiolated Seedlings of Arabidopsis Using a Fluorescent Differential Display Technique
2000
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7
1994 Science
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Emerging Targets in Photopharmacology
2016 StandoutNobel
Altered peptidase and viral-specific T cell response in LMP2 mutant mice
1994 StandoutNobel
Efficient Total Synthesis of Novel Bioactive Microbial Metabolites
2008 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.
1994
Biogenesis, structure and function of the yeast 20S proteasome.
1995
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.
1994
G-protein-coupled Receptor (GPCR) Kinase Phosphorylation and β-Arrestin Recruitment Regulate the Constitutive Signaling Activity of the Human Cytomegalovirus US28 GPCR
2003 StandoutNobel
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of James Chambers being referenced
Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease
2011
Inhibition of calcium channel dihydropyridine receptor binding by purified Mojave toxin
1989
Cloning differentially expressed mRNAs
1996
Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules.
1992
Alternative exon usage and processing of the major histocompatibility complex-encoded proteasome subunits.
1992
DNA Microarrays of the Complex Human Cytomegalovirus Genome: Profiling Kinetic Class with Drug Sensitivity of Viral Gene Expression
1999
Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice
2014
Indirect Comparison of the Efficacy of Melphalan-Prednisone-Bortezomib Relative to Melphalan-Prednisone-Thalidomide and Melphalan-Prednisone for the First Line Treatment of Multiple Myeloma
2008
Absence of abnormal erythrocyte superoxide dismutase, copper, or zinc levels in patients with retinitis pigmentosa.
1982