Citation Impact
Citing Papers
A Network of Control Mediated by Regulator of Calcium/Calmodulin-Dependent Signaling
2004 Science
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Mechanism of Regulation of Casein Kinase I Activity by Group I Metabotropic Glutamate Receptors
2002
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
1999 Nature
Experimental Genetic Approaches to Addiction
2002
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Fitting atomic models into electron-microscopy maps
2000
An update on the mechanisms of the psychostimulant effects of caffeine
2007
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
Inhibitory Phosphorylation of Glycogen Synthase Kinase-3 (GSK-3) in Response to Lithium
2003
Apoptosis in the nervous system
2000 StandoutNature
A Study of the Involvement of Melanin-Concentrating Hormone Receptor 1 (MCHR1) in Murine Models of Depression
2006
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
GSK3 takes centre stage more than 20 years after its discovery
2001
The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
2001 Standout
Are Huntington’s and polyglutamine-based ataxias proteasome storage diseases?
2003
AKT/PKB Signaling: Navigating Downstream
2007 Standout
ΔFosB: a molecular switch for long-term adaptation in the brain
2004
Regulation of gene expression and cocaine reward by CREB and ΔFosB
2003
Engineering receptors in the secretory pathway for orthogonal signalling control
2022
Dopamine D1 receptor–mediated aggregation of N-terminal fragments of mutant huntingtin and cell death in a neuroblastoma cell line
2008
3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3)
2001
Incubation of cocaine craving after withdrawal: a review of preclinical data
2004
Identification of PSD-95 as a Regulator of Dopamine-Mediated Synaptic and Behavioral Plasticity
2004
Cyclin‐dependent kinase inhibitors for treating cancer
2001
Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest
2001
SynCAM 1 Adhesion Dynamically Regulates Synapse Number and Impacts Plasticity and Learning
2010 StandoutNobel
Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect
2004
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Repeated exposure to amphetamine disrupts dopaminergic modulation of excitatory synaptic plasticity and neurotransmission in nucleus accumbens
2003
Agonist-regulated Interaction between α2-Adrenergic Receptors and Spinophilin
2001
The Neural Basis of Addiction: A Pathology of Motivation and Choice
2005 Standout
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine
2001
Bacterial Lipopolysaccharide Binding Enhances Virion Stability and Promotes Environmental Fitness of an Enteric Virus
2014
Intracellular Targets of Paullones
2002
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Dopamine and Glutamate Induce Distinct Striatal Splice Forms of Ania-6, an RNA Polymerase II-Associated Cyclin
2001
Cdk5 deregulation in the pathogenesis of Alzheimer's disease
2004
New approaches to antidepressant drug discovery: beyond monoamines
2006
Efficacy of the MCHR1 Antagonist N-[3-(1-{[4-(3,4-Difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]-2-methylpropanamide (SNAP 94847) in Mouse Models of Anxiety and Depression following Acute and Chronic Administration Is Independent of Hippocampal Neurogenesis
2007
Addiction and the brain: The neurobiology of compulsion and its persistence
2001
Molecular mechanisms of drug addiction
2004
Cocaine Self-Administration in Mice Is Inversely Related to Phosphorylation at Thr34 (Protein Kinase A Site) and Ser130 (Kinase CK1 Site) of DARPP-32
2006
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Metabolic Delivery of Ketone Groups to Sialic Acid Residues
1998 StandoutNobel
Activator of G Protein Signaling 3
2004
Interaction of Neuronal Cdc2-like Protein Kinase with Microtubule-associated Protein Tau
2000
Neurotrophic Mechanisms in Drug Addiction
2004
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
R7BP Complexes With RGS9-2 and RGS7 in the Striatum Differentially Control Motor Learning and Locomotor Responses to Cocaine
2009
CYY-1/Cyclin Y and CDK-5 Differentially Regulate Synapse Elimination and Formation for Rewiring Neural Circuits
2011
Cannabinoid Action Depends on Phosphorylation of Dopamine- and cAMP-Regulated Phosphoprotein of 32 kDa at the Protein Kinase A Site in Striatal Projection Neurons
2005
Genetic NMDA Receptor Deficiency Disrupts Acute and Chronic Effects of Cocaine but not Amphetamine
2008
Molecular and cellular events of dopamine D1 receptor‐mediated tau phosphorylation in SK‐N‐MC cells
2010
Glycogen synthase kinase 3 (GSK‐3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
2002
The Mesolimbic Dopamine Reward Circuit in Depression
2006 Standout
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
2008
Alzheimer's Disease
2010 Standout
Decoding the Epigenetic Language of Neuronal Plasticity
2008
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Chromatin Remodeling Is a Key Mechanism Underlying Cocaine-Induced Plasticity in Striatum
2005
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Cytochrome p450 enzymes in the generation of commercial products
2002
Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice
2009
LTP Inhibits LTD in the Hippocampus via Regulation of GSK3β
2007
Dopamine Receptor Signaling
2004
The molecular and cellular biology of enhanced cognition
2009
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
2005 Nature
Synthesis and Microcontact Printing of Dual End‐Functionalized Mucin‐like Glycopolymers for Microarray Applications
2009 StandoutNobel
Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Contributes to the Development of Nigro-Striatal Damage Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
2004
A decade of CDK5
2001
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
Cdk5 Regulates the Phosphorylation of Tyrosine 1472 NR2B and the Surface Expression of NMDA Receptors
2008
Increased D1 dopamine receptor signaling in levodopa‐induced dyskinesia
2004
Structural plasticity associated with exposure to drugs of abuse
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
The Neurobiology of Dopamine Signaling
2004
The molecular neurobiology of depression
2008 StandoutNature
Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement
2003 StandoutNobel
Selective Neuronal Degeneration in Huntington's Disease
2006
An association study between PPP1R1B gene and schizophrenia in the Chinese population
2007
Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
2007
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine
2003
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions
2001 StandoutNobel
A phosphatase cascade by which rewarding stimuli control nucleosomal response
2008 Nature
Striatal Cell Type-Specific Overexpression of ΔFosB Enhances Incentive for Cocaine
2003
Psychomotor stimulant addiction: a neural systems perspective.
2002
Dopamine Enhancement of NMDA Currents in Dissociated Medium-Sized Striatal Neurons: Role of D1 Receptors and DARPP-32
2002
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
2003
Consequences of a subtle sialic acid modification on the murine polyomavirus receptor
1997
Mechanisms of transcriptional dysregulation in Huntington's disease
2003
Epigenetic regulation in psychiatric disorders
2007
Neurodegenerative Tauopathies
2001 Standout
ΔFosB: A sustained molecular switch for addiction
2001
Aloisines, a New Family of CDK/GSK-3 Inhibitors. SAR Study, Crystal Structure in Complex with CDK2, Enzyme Selectivity, and Cellular Effects
2002
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress
2006 StandoutScience
DARPP-32: An Integrator of Neurotransmission
2004
A Century of Alzheimer's Disease
2006 StandoutScience
A role for autophagy in long‐term spatial memory formation in male rodents
2017
The Neurobiology of Slow Synaptic Transmission
2001 Science
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Psychomotor Stimulant Addiction: A Neural Systems Perspective
2002
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
2004
The specificities of protein kinase inhibitors: an update
2003 Standout
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
2004 StandoutNobel
Diverse Psychotomimetics Act Through a Common Signaling Pathway
2003 Science
GSK-3: tricks of the trade for a multi-tasking kinase
2003 Standout
Molecular Neurobiology of Drug Addiction
2004
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
2004
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
2004
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
First Non-ATP Competitive Glycogen Synthase Kinase 3 β (GSK-3β) Inhibitors: Thiadiazolidinones (TDZD) as Potential Drugs for the Treatment of Alzheimer's Disease
2002
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren
1998
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
2001
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Enteric bacteria promote human and mouse norovirus infection of B cells
2014 StandoutScience
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory
2006 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of James Bibb being referenced
7 Poliovirus Receptors
1994
Impairment of hippocampal long‐term depression and defective spatial learning and memory in p35–/– mice
2005
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
2001 Nature
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5
2003
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
2001
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
2000
Alternative roles for Cdk5 in learning and synaptic plasticity
2007
Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5
2001
The Human Poliovirus Receptor
1995
Regulation of DARPP‐32 dephosphorylation at PKA‐ and Cdk5‐sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase‐2A
2002
Cognition Enhancement Strategies: Figure 1.
2010
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia
2000
The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance
2005
Role of Cdk5 in Neuronal Signaling, Plasticity, and Drug Abuse
2003
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
2002 Nature
Roscovitine: a novel regulator of P/Q‐type calcium channels and transmitter release in central neurons
2002
Control of cyclin‐dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability
2005
Interaction of Poliovirus with its Cell Surface Binding Site
1994
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
1999 Nature
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation
2007
Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance
2020
Requirement for DARPP-32 in Progesterone-Facilitated Sexual Receptivity in Female Rats and Mice
2000 Science
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine
2007
Cdk5 is essential for adult hippocampal neurogenesis
2008
Developmental Regulation of the Proteolysis of the p35 Cyclin-Dependent Kinase 5 Activator by Phosphorylation
2003
Amplification of dopaminergic signaling by a positive feedback loop
2000
Cdk5 and the mystery of synaptic vesicle endocytosis
2003
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
2000
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology
2008
Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors
2001