Citation Impact
Citing Papers
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
2018 StandoutScienceNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus
1997 Standout
Cell-penetrating peptides
2000
Protein transduction: unrestricted delivery into all cells?
2000
Manipulation of cell surface macromolecules by flaviviruses
2003
Molecular mechanisms of the biological activity of the anticancer drug elesclomol and its complexes with Cu(II), Ni(II) and Pt(II)
2013
Mapping proteinDNA interactions in vivo with formaldehyde: Evidence that histone H4 is retained on a highly transcribed gene
1988
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
2004 Standout
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Twenty years of cell‐penetrating peptides: from molecular mechanisms to therapeutics
2009
Cell-penetrating Peptides
2002
Cholera Toxin B Subunit Shows Transneuronal Tracing after Injection in an Injured Sciatic Nerve
2015
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
Antitumour actions of interferons: implications for cancer therapy
2016
Cell surface adherence and endocytosis of protein transduction domains
2003
Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
2014
Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-κB signaling
2010
Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
2007
Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
2000
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Mitochondrial metabolism promotes adaptation to proteotoxic stress
2019
Vectorial delivery of macromolecules into cells using peptide-based vehicles
2001
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
1998
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
2004
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
The cytotoxicity of the anticancer drug elesclomol is due to oxidative stress indirectly mediated through its complex with Cu(II)
2014
Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer
2013 StandoutNobel
Virus-based nanocarriers for drug delivery
2012
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Creation of a zymogen
2002
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Intercellular Trafficking and Protein Delivery by a Herpesvirus Structural Protein
1997
Role of the alpha-amino group of protein in ubiquitin-mediated protein breakdown.
1984 StandoutNobel
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
1991 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Degradation of Proteins with Acetylated Amino Termini by the Ubiquitin System
1989 StandoutScienceNobel
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Role of arginine-tRNA in protein degradation by the ubiquitin pathway
1987 StandoutNatureNobel
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
2000
Biomedical applications of copper ionophores
2020
Immunoelectron microscopic localization of ubiquitin in hepatoma cells.
1988 StandoutNobel
Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit
2019
The ubiquitin‐mediated proteolytic pathway and mechanisms of energy‐dependent intracellular protein degradation
1984 StandoutNobel
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.
1984 StandoutNobel
Prooxidant States and Tumor Promotion
1985 StandoutScience
Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus.
1989
Nucleosome disruption precedes transcription and is largely limited to the transcribed domain of globin genes in murine erythroleukemia cells
1985
Ku is associated with the telomere in mammals
1999 StandoutNobel
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes.
1987 StandoutNobel
Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome
1982
Eukaryotic RNA polymerase II binds to nucleosome cores from transcribed genes
1983 Nature
Breaching Biological Barriers: Protein Translocation Domains as Tools for Molecular Imaging and Therapy
2003
E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins.
1996 StandoutNobel
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.
1984 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85
1984 StandoutNobel
Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system.
1985 StandoutNobel
Phase II, Randomized, Controlled, Double-Blinded Trial of Weekly Elesclomol Plus Paclitaxel Versus Paclitaxel Alone for Stage IV Metastatic Melanoma
2009
Gene amplification in cultured animal cells
1984
DNA topoisomerases: why so many?
1991
ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin.
1989 StandoutNobel
Nucleosomes are phased along the mouse β-major globin gene in erythroid and nonerythroid cells
1986 StandoutNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Variegated chromatin structures of mouse ribosomal RNA genes
1983
Transfer RNA is required for conjugation of ubiquitin to selective substrates of the ubiquitin- and ATP-dependent proteolytic system.
1986 StandoutNobel
TAPping into mRNA Export
2001 StandoutScienceNobel
The RAD6 protein of Saccharomyces cerevisiae polyubiquitinates histones, and its acidic domain mediates this activity.
1988
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Oncogene Amplification in Tumor Cells
1986
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85
1984 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Breaching Biological Barriers: Protein Translocation Domains as Tools for Molecular Imaging and Therapy
2003
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Chromatin structure of the molecular ends of oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex
1984 StandoutNobel
The Ubiquitin Pathway for the Degradation of Intracellular Proteins
1986 StandoutNobel
Final Results of Phase III SYMMETRY Study: Randomized, Double-Blind Trial of Elesclomol Plus Paclitaxel Versus Paclitaxel Alone As Treatment for Chemotherapy-Naive Patients With Advanced Melanoma
2013
In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse
1999 StandoutScience
Works of James Barsoum being referenced
Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy
2011
Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non–Small Cell Lung Cancer
2012
Elesclomol induces cancer cell apoptosis through oxidative stress
2008
The oxidative stress inducer STA-4783 enhances the in vivo efficacy of multiple anti-cancer therapies in mouse tumor models
2007
Effects of the guanine-quadruplex telomerase inhibitor BRACO-19 on tumour cells: Evidence of selective action on telomere maintenance
2004
Preferential localization of variant nucleosomes near the 5'-end of the mouse dihydrofolate reductase gene.
1985
The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells
2012
Specific Inhibition of a Human Papillomavirus E2 Trans -Activator by Intracellular Delivery of Its Repressor
1994
Sequestration of Adenoviral Vector by Kupffer Cells Leads to a Nonlinear Dose Response of Transduction in Liver
2001
Baculovirus vector requires electrostatic interactions including heparan sulfate for efficient gene transfer in mammalian cells
1999
Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells
2009
Efficient Transduction of Mammalian Cells by a Recombinant Baculovirus Having the Vesicular Stomatitis Virus G Glycoprotein
1997
Increased Cellular Uptake of the Human Immunodeficiency Virus-1 Tat Protein after Modification with Biotin
1995
Stat1-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand and the cell-surface death signaling pathway by interferon beta in human cancer cells.
2003
Two-dimensional hybridization mapping of nucleosomes
1981
Cellular and SV40 Chromatin: Replication, Segregation, Ubiqiritination, Nuclease-hypersensitive Sites, HMG-containing Nueleosomes, and Heterochromatin-specific Protein
1983
New way to isolate simian virus 40 nucleoprotein complexes from infected cells: use of a thiol-specific reagent
1982
Tat-mediated delivery of heterologous proteins into cells.
1994
Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes.
1983
Abstract C11: The oxidative stress inducer elesclomol requires copper chelation for its anticancer activity
2009