Citation Impact

Citing Papers

Identity of the elusive IgM Fc receptor (FcμR) in humans
2009
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
IL-25 regulates Th17 function in autoimmune inflammation
2007
Cancer Regression in Patients After Transfer of Genetically Engineered Lymphocytes
2006 StandoutScience
Mouse IgM Fc Receptor, FCMR, Promotes B Cell Development and Modulates Antigen-Driven Immune Responses
2012
Cytokine Gene Therapy in Experimental Allergic Encephalomyelitis by Injection of Plasmid DNA-Cationic Liposome Complex into the Central Nervous System
1998
Gene Therapy of Arthritis with TCR Isolated from the Inflamed Paw
2006
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
2013
Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization
2015
Hallmarks of Cancer: The Next Generation
2011 Standout
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
The application of anti-Toso antibody enhances CD8+ T cell responses in experimental malaria vaccination and disease
2015
Type 2 cytokines: mechanisms and therapeutic strategies
2015
Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
2011
The perivascular niche regulates breast tumour dormancy
2013
Hypoxia-inducible Mammalian Gene Expression Analyzed in Vivo at a TATA-driven Promoter and at an Initiator-driven Promoter
1998
Oncogenic kinase signalling
2001 StandoutNature
Engineering and characterization of a superfolder green fluorescent protein
2005 Standout
Anaplastic lymphoma kinase proteins in growth control and cancer
2004
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
T-cell-receptor gene therapy
2002
Intracellular phospho‐protein staining techniques for flow cytometry: Monitoring single cell signaling events
2003
CD4+ T-cell subsets in autoimmunity
1997
Regulatory T Cells
2000 StandoutNobel
The Old but New IgM Fc Receptor (FcμR)
2014
Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq
2010
Systematic identification of regulatory proteins critical for T-cell activation
2003
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
The Use of Induced Pluripotent Stem Cells in Drug Development
2011 StandoutNobel
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Double-Stranded RNA Injection Produces Null Phenotypes in Zebrafish
2000
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Pax6 Is a Human Neuroectoderm Cell Fate Determinant
2010
Development of 2A peptide-based strategies in the design of multicistronic vectors
2005
The Role of IL-10 in Mouse Hepatitis Virus-Induced Demyelinating Encephalomyelitis
1998
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Authentic IgM Fc Receptor (FcμR)
2017
The design of reversible hydrogels to capture extracellular matrix dynamics
2016
Surface receptor Toso controls B cell–mediated regulation of T cell immunity
2018
Functional analysis of the N-terminal domain of the Myc oncoprotein
2003
A simple ImageJ macro tool for analyzing mitochondrial network morphology in mammalian cell culture
2017
Stem cells in tumor angiogenesis
2010
EMT: 2016
2016 Standout
The Mouse Cell Surface Protein TOSO Regulates Fas/Fas Ligand-induced Apoptosis through Its Binding to Fas-associated Death Domain
2005
Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis
2016
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Cloning of the zebrafishkrox-20gene (krx-20) and its expression during hindbrain development
1993
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
2011 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity
2015
Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
2012
The Long Elusive IgM Fc Receptor, FcμR
2014
Identification of TOSO/FAIM3 as an Fc receptor for IgM
2009
Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs
2011
The IgM receptor FcμR limits tonic BCR signaling by regulating expression of the IgM BCR
2017
Pericytes and vessel maturation during tumor angiogenesis and metastasis
2010
Functional Roles of the IgM Fc Receptor in the Immune System
2019 StandoutNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
Overexpression of TOSO in CLL is triggered by B-cell receptor signaling and associated with progressive disease
2008
Treatment of Experimental Autoimmune Encephalomyelitis with Genetically Modified Memory T Cells
1997
Dysregulation of Apoptosis in Cancer
1999
DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2
2000 Science
An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
1998
TOSO, the Fcμ Receptor, Is Highly Expressed on Chronic Lymphocytic Leukemia B Cells, Internalizes upon IgM Binding, Shuttles to the Lysosome, and Is Downregulated in Response to TLR Activation
2011
Rab3D Is Not Required for Exocrine Exocytosis but for Maintenance of Normally Sized Secretory Granules
2002 StandoutNobel
Coupling of Peripheral Tolerance to Endogenous Interleukin 10 Promotes Effective Modulation of Myelin-Activated T Cells and Ameliorates Experimental Allergic Encephalomyelitis
2000
CD4+CD25LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Sequence–Structure–Binding Relationships Reveal Adhesion Behavior of the Car9 Solid-Binding Peptide: An Integrated Experimental and Simulation Study
2020 StandoutNobel
Toso, a Functional IgM Receptor, Is Regulated by IL-2 in T and NK Cells
2012
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.
1996 StandoutNobel
Central Nervous System Expression of IL-10 Inhibits Autoimmune Encephalomyelitis
2001
Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia
2011
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Unique Ligand-Binding Property of the Human IgM Fc Receptor
2015
Integrin Signaling
1999 StandoutScience
Nomenclature of Toso, Fas Apoptosis Inhibitory Molecule 3, and IgM FcR
2015
First Axl inhibitor enters clinical trials
2013
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells
2014
Surfing the p53 network
2000 StandoutNature
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination
2011
Honokiol: A Review of Its Anticancer Potential and Mechanisms
2019
Efficient Multicistronic Expression of a Transgene in Human Embryonic Stem Cells
2007
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
IL-10 Is Critical in the Regulation of Autoimmune Encephalomyelitis as Demonstrated by Studies of IL-10- and IL-4-Deficient and Transgenic Mice
1998
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis
1999
Emerging Targets in Photopharmacology
2016 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses
2012
Nonpeptide Tachykinin Receptor Antagonists. II. Pharmacological and Pharmacokinetic Profile of SB-222200, a Central Nervous System Penetrant, Potent and Selective NK-3 Receptor Antagonist
2000
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
SAGE analysis demonstrates increased expression of TOSO contributing to Fas-mediated resistance in CLL
2008
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice
2014
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel

Works of James B. Lorens being referenced

Activation of the PKB/AKT Pathway by ICAM-2
2002
Retroviral Delivery of Peptide Modulators of Cellular Functions
2000
Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay
1999
Neurokinin-3 receptor distribution in rat and human brain: an immunohistochemical study
1999
Rapid and reliable cloning of PCR products.
1991
Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer
2010
Dominant effector genetics in mammalian cells
2001
Embryonic Expression and DNA-Binding Properties of Zebrafish Pax-6
1995
Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC
2019
Automated Quantification and Integrative Analysis of 2D and 3D Mitochondrial Shape and Network Properties
2014
High content screening: seeing is believing
2010
Mural Cell Associated VEGF Is Required for Organotypic Vessel Formation
2009
Intracellular protein scaffold-mediated display of random peptide libraries for phenotypic screens in mammalian cells
2001
The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics
2001
Stable, stoichiometric delivery of diverse protein functions
2003
Toso, a Cell Surface, Specific Regulator of Fas-Induced Apoptosis in T Cells
1998
Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome
2009
Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival
2009
Rapid Production of Retroviruses for Efficient Gene Delivery to Mammalian Cells Using 293T Cell–Based Systems
1999
Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis
1997
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