Citation Impact
Citing Papers
Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
2009 StandoutScienceNobel
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
Cycling vrille Expression Is Required for a Functional Drosophila Clock
1999 StandoutNobel
The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
2011
Plug-and-Play Genetic Access to Drosophila Cell Types using Exchangeable Exon Cassettes
2015
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Transcriptional repression of eukaryotic promoters
1989
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos
1989
The Drosophila fushi tarazu polypeptide is a DNA-binding transcriptional activator in yeast cells
1989 Nature
The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
1990
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein
1994 StandoutNatureNobel
The Eph family in retinal axon guidance
1997
Direct homeodomain–DNA interaction in the autoregulation of the fushi tarazu gene
1992 Nature
A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers
2010
Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells
1989
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
1998 StandoutNobel
Methylation of Lysine 4 on Histone H3: Intricacy of Writing and Reading a Single Epigenetic Mark
2007
Nitric Oxide as a Switching Mechanism between Axon Degeneration and Regrowth during Developmental Remodeling
2016
The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
1990 Standout
Skeletal muscles of mice deficient in muscle creatine kinase lack burst activity
1993
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Genome Regulation by Polycomb and Trithorax Proteins
2007
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
1989
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Coordinated expression of ncRNAs and HOX mRNAs in the human HOXA locus
2007
Transcription regulation and animal diversity
2003 Nature
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Caenorhabditis elegans has scores of homoeobox-containing genes
1989 StandoutNatureNobel
Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells
1989
Membrane Fusion
2003 StandoutNobel
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
1989 StandoutNobel
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
2011 StandoutNature
The gradient morphogen bicoid is a concentration-dependent transcriptional activator
1989
C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
1992 StandoutNatureNobel
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
The lncRNA Malat1 Is Dispensable for Mouse Development but Its Transcription Plays a cis-Regulatory Role in the Adult
2012
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
Homeodomain-DNA recognition
1994 StandoutNobel
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
2007 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Functional dissection of ultrabithorax proteins in D. melanogaster
1990
The specificities of sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain
1990
Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen
1989 StandoutNatureNobel
Expression of a large family of POU-domain regulatory genes in mammalian brain development
1989 Nature
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9
1989
What determines the specificity of action of Drosophila homeodomain proteins?
1990
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
A universal target sequence is bound in vitro by diverse homeodomains
1993
Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy
2017
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
In vivo analysis of the helix-turn-helix motif of the fushi tarazu homeo domain of Drosophila melanogaster.
1992
Analysis of a fushi tarazu autoregulatory element: multiple sequence elements contribute to enhancer activity.
1993
Transcriptional repression by a novel member of the bZIP family of transcription factors.
1992
Directing Cell Division During Development
1989 Science
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification
2004
Extensive Nuclear DNA Sequence Diversity Among Chimpanzees
1999 StandoutScienceNobel
Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos
1990
A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.
1989
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Skeletal muscle phenotypes initiated by ectopic MyoD in transgenic mouse heart
1992
Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis.
1997
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.
1989
Homeotic gene expression in the visceral mesoderm of Drosophila embryos.
1989
Expression and embryonic function of empty spiracles: a Drosophila homeo box gene with two patterning functions on the anterior-posterior axis of the embryo.
1989
Analysis of the ftz upstream element: germ layer-specific enhancers are independently autoregulated.
1990
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury
2010
In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR
1989 Science
Body-Wall Muscle Formation in Caenorhabditis elegans Embryos that Lack the MyoD Homolog hlh-1
1992 StandoutScienceNobel
Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity.
1990 StandoutNobel
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene.
1991
Evidence for Developmentally Programmed Transdifferentiation in Mouse Esophageal Muscle
1995 StandoutScienceNobel
DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila
2012
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy
2017
Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.
1996
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Swift Is a Novel BRCT Domain Coactivator of Smad2 in Transforming Growth Factor β Signaling
2001 StandoutNobel
The molecular clock runs more slowly in man than in apes and monkeys
1987 Nature
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.
1991
Works of James B. Jaynes being referenced
Ecdysone- and NO-Mediated Gene Regulation by Competing EcR/Usp and E75A Nuclear Receptors during Drosophila Development
2011
Expression of a transfected mouse muscle-creatine kinase gene is induced upon growth factor deprivation of myogenic but not of nonmyogenic cells
1989
Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric oxide synthase and Fd59a/Fox-D
2014
Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference
2006
Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila
1999
Activation and repression of transcription by homoeodomain-containing proteins that bind a common site
1988 Nature
The Muscle Creatine Kinase Gene Is Regulated by Multiple Upstream Elements, Including a Muscle-Specific Enhancer
1988
Transcriptional Regulation of the Muscle Creatine Kinase Gene and Regulated Expression in Transfected Mouse Myoblasts
1986
Regulation of creatine kinase induction in differentiating mouse myoblasts.
1985
Regulation of Creatine Kinase Induction in Differentiating Mouse Myoblasts
1985
A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo
1996
Even-skipped, acting as a repressor, regulates axonal projections inDrosophila
2003
Active repression of transcription by the engrailed homeodomain protein.
1991
Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.
1986
Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients*
1999
The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.
1988
The mouse muscle creatine kinase cDNA and deduced amino acid sequences: Comparison to evolutionarily related enzymes
1985