Citation Impact
Citing Papers
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
The Internalization and Degradation of Human Copper Transporter 1 following Cisplatin Exposure
2006
Cells have distinct mechanisms to maintain protection against different reactive oxygen species: Oxidative-stress-response genes
2004
Biosynthesis of fluopsin C, a copper-containing antibiotic from Pseudomonas aeruginosa
2021 Science
Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria
2005 StandoutScience
Copper Chelation Inhibits BRAFV600E-Driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors
2017
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Transitive functional annotation by shortest-path analysis of gene expression data
2002
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
WGCNA: an R package for weighted correlation network analysis
2008 Standout
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA
2009
A novel copper‐responsive regulon in Mycobacterium tuberculosis
2010
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Abiotic Stress Signaling and Responses in Plants
2016 Standout
CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator
2006
Global analysis of protein expression in yeast
2003 StandoutNature
Antiproliferative activity and QSAR study of copper(II) mixed chelate [Cu(N–N)(acetylacetonato)]NO3 and [Cu(N–N)(glycinato)]NO3 complexes, (Casiopeínas®)
2008
Energetics of Copper Trafficking between the Atx1 Metallochaperone and the Intracellular Copper Transporter, Ccc2
2000
Radical-induced DNA damage by cytotoxic square-planar copper(II) complexes incorporating o-phthalate and 1,10-phenanthroline or 2,2′-dipyridyl
2012
Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance
2006
The role of copper transporters in the development of resistance to Pt drugs
2004
Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast
2000
Molecular Characterization of hCTR1, the Human Copper Uptake Protein
2002
The Independent cue and cusSystems Confer Copper Tolerance during Aerobic and Anaerobic Growth inEscherichia coli
2001
Metallobiology of host–pathogen interactions: an intoxicating new insight
2012
Copper Homeostasis in Salmonella Is Atypical and Copper-CueP Is a Major Periplasmic Metal Complex
2010
Genetic Defects in Copper Metabolism
2003
Modulation of the cellular pharmacology of JM118, the major metabolite of satraplatin, by copper influx and efflux transporters
2005
Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
2008 Standout
Human copper homeostasis: a network of interconnected pathways
2010
Getting in and out of the proteasome
2000
Pipes and wiring: the regulation of copper uptake and distribution in yeast
1999
Nutritional immunity: transition metals at the pathogen–host interface
2012 Standout
Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat
2005
Parallel and comparative analysis of the proteome and transcriptome of sorbic acid‐stressed Saccharomyces cerevisiae
2001
Molecular and Cellular Aspects of Copper Transport in Developing Mammals
2003
Trace elements in human physiology and pathology. Copper
2003
Coordination chemistry of copper proteins: How nature handles a toxic cargo for essential function
2011
Iron and copper metabolism
2005
Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes
2012
Copper transporters regulate the cellular pharmacology and sensitivity to Pt drugs
2004
The resurgence of platinum-based cancer chemotherapy
2007 Standout
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Intracellular Copper Transport in Mammals
2004
Copper(II) protects yeast against the toxicity of cisplatin independently of the induction of metallothionein and the inhibition of platinum uptake
2003
A PCBP1–BolA2 chaperone complex delivers iron for cytosolic [2Fe–2S] cluster assembly
2019
Copper in diseases and treatments, and copper‐based anticancer strategies
2009
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
The Enterococcus hirae paradigm of copper homeostasis: Copper chaperone turnover, interactions, and transactions
2003
Protein Oxidation in G0 Cells of Saccharomyces cerevisiae Depends on the State Rather than Rate of Respiration and Is Enhanced in pos9 but Notyap1 Mutants
2001
Stable Plasma Membrane Levels of hCTR1 Mediate Cellular Copper Uptake
2005
Copper Homeostasis in the CNS: A Novel Link Between the NMDA Receptor and Copper Homeostasis in the Hippocampus
2006
Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator
2010
Molecular mechanisms of cisplatin resistance
2011 Standout
Membrane transport of hydrogen peroxide
2006
Redox characteristics of the eukaryotic cytosol
2007
The Copper Influx Transporter Human Copper Transport Protein 1 Regulates the Uptake of Cisplatin in Human Ovarian Carcinoma Cells
2004
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The roles of copper transporters in cisplatin resistance
2007
Cellular Responses to Cisplatin‐Induced DNA Damage
2010
Cellular processing of platinum anticancer drugs
2005 Standout
Cisplatin resistance: Preclinical findings and clinical implications
2010
Charting the travels of copper in eukaryotes from yeast to mammals
2012
Brain Copper Content and Cuproenzyme Activity Do Not Vary with Prion Protein Expression Level
2000
The Copper Transporter CTR1 Regulates Cisplatin Uptake in Saccharomyces cerevisiae
2002
The Transcriptional Response of Saccharomyces cerevisiae to Osmotic Shock
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma
2020
A Molecular Mechanism for Bacterial Susceptibility to Zinc
2011
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Reserve carbohydrates metabolism in the yeastSaccharomyces cerevisiae
2001
XIAP: Cell death regulation meets copper homeostasis
2007
Cross-resistance to cisplatin in cells with acquired resistance to copper
2004
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
A Red Carpet for Iron Metabolism
2017
ThesctRofSalmonella entericaserova Typhimurium encoding a homologue of MerR protein is involved in the copper-responsive regulation ofcuiD
2002
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Mutant SOD1 causes motor neuron disease independent of copper chaperone–mediated copper loading
2002
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Copper in Microbial Pathogenesis: Meddling with the Metal
2012
Turning Tumor-Promoting Copper into an Anti-Cancer Weapon via High-Throughput Chemistry
2010
A synthetic dinuclear copper(II) hydrolase and its potential as antitumoral: Cytotoxicity, cellular uptake, and DNA cleavage
2009
Metallochaperones and Metal-Transporting ATPases: A Comparative Analysis of Sequences and Structures
2002
Cisplatin in cancer therapy: Molecular mechanisms of action
2014 Standout
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
2002 StandoutNobel
Four years of post‐genomic life with 6000 yeast genes
2000
The Hallmarks of Aging
2013 Standout
Contribution of the Major Copper Influx Transporter CTR1 to the Cellular Accumulation of Cisplatin, Carboplatin, and Oxaliplatin
2006
Anaemia in kidney disease: harnessing hypoxia responses for therapy
2015
Copper Complexes as Anticancer Agents
2009
CtpV: a putative copper exporter required for full virulence of Mycobacterium tuberculosis
2010
Role of the Copper Transporter, CTR1, in Platinum-Induced Ototoxicity
2010
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Molecular mechanisms of copper uptake and distribution
2002
Copper Transport Protein (Ctr1) Levels in Mice Are Tissue Specific and Dependent on Copper Status
2006
Human Macrophage ATP7A is Localized in the trans-Golgi Apparatus, Controls Intracellular Copper Levels, and Mediates Macrophage Responses to Dermal Wounds
2011
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
Copper: An essential metal in biology
2011
Trafficking of a Secretory Granule Membrane Protein Is Sensitive to Copper
2007
Copper Chaperones for Cytochrome c Oxidase and Human Disease
2002
Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity
2011
Copper is required for oncogenic BRAF signalling and tumorigenesis
2014 Nature
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity
2010
The N‐terminal copper‐binding domain of the amyloid precursor protein protects against Cu 2+ neurotoxicity in vivo
2004
Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosis
2001
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Copper Control as an Antiangiogenic Anticancer Therapy: Lessons from Treating Wilson's Disease
2001
Genome-Wide Transcriptional Profiling of the Escherichia coli Responses to Superoxide Stress and Sodium Salicylate
2001
Transferrin receptor 1 in cancer: a new sight for cancer therapy.
2018
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Osmotic Stress Signaling and Osmoadaptation in Yeasts
2002
CopA: An Escherichia coli Cu(I)-translocating P-type ATPase
2000
The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy
2007
Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae
2015 StandoutNobel
Tomato abiotic stress enhanced tolerance by trehalose biosynthesis
2005
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae
2007
IRON REGULATORY PROTEINS AND THE MOLECULAR CONTROL OF MAMMALIAN IRON METABOLISM
2000
Global response of Saccharomyces cerevisiae to an alkylating agent
1999
Multiple Sclerosis
2018 Standout
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Molecular Features of the Copper Binding Sites in the Octarepeat Domain of the Prion Protein
2002
Structural Biology of Copper Trafficking
2009
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy
2010
Essential role for Atox1 in the copper-mediated intracellular trafficking of the Menkes ATPase
2003
Copper-Dependent Cytotoxicity of 8-Hydroxyquinoline Derivatives Correlates with Their Hydrophobicity and Does Not Require Caspase Activation
2012
A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
2012
Mechanisms for copper acquisition, distribution and regulation
2008
Copper and Iron Disorders of the Brain
2007
Luminescent Functional Metal–Organic Frameworks
2011 Standout
Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages
2011
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
The iron chaperone and nucleic acid–binding activities of poly(rC)-binding protein 1 are separable and independently essential
2021
Broken Limits to Life Expectancy
2002 StandoutScience
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Copper resistance is essential for virulence of Mycobacterium tuberculosis
2011
Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1)
2002
Phenotypic Characterization of acopAMutant of Neisseria gonorrhoeae Identifies a Link between Copper and Nitrosative Stress
2011
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Bioavailable copper modulates oxidative phosphorylation and growth of tumors
2013
Regenerative Capacity of Macrophages for Remyelination
2016
Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper.
2002
Copper Metallochaperones
2010
Direct Cellular Responses to Platinum-Induced DNA Damage
2007
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Copper and Alzheimer's disease
2007
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Copper-related diseases: From chemistry to molecular pathology
2009
Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)
2009
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Increased Expression of the Copper Efflux Transporter ATP7A Mediates Resistance to Cisplatin, Carboplatin, and Oxaliplatin in Ovarian Cancer Cells
2004
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Copper Reduction by the Octapeptide Repeat Region of Prion Protein: pH Dependence and Implications in Cellular Copper Uptake
2005
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
PHYTOCHELATINS AND METALLOTHIONEINS : Roles in Heavy Metal Detoxification and Homeostasis
2002 Standout
Altered copper homeostasis underlies sensitivity of hepatocellular carcinoma to copper chelation
2020
Works of Jaekwon Lee being referenced
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
2002
Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α
2013
Identification of Methionine-rich Clusters That Regulate Copper-stimulated Endocytosis of the Human Ctr1 Copper Transporter
2004
Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation
2015
Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant
2000
Yap1 and Skn7 Control Two Specialized Oxidative Stress Response Regulons in Yeast
1999
Copper Transport Activity of Yeast Ctr1 Is Down-regulated via Its C Terminus in Response to Excess Copper
2008
Biochemical Characterization of the Human Copper Transporter Ctr1
2002
A Role for the ATP7A Copper-transporting ATPase in Macrophage Bactericidal Activity
2009
Characterization of Mouse Embryonic Cells Deficient in the Ctr1 High Affinity Copper Transporter
2002
Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis
2008
Distinct Mechanisms for Ctr1-mediated Copper and Cisplatin Transport
2007
Biochemical and Genetic Analyses of Yeast and Human High Affinity Copper Transporters Suggest a Conserved Mechanism for Copper Uptake
2002
Mobilization of Intracellular Copper Stores by the Ctr2 Vacuolar Copper Transporter
2004
The H2O2 Stimulon in Saccharomyces cerevisiae
1998
A New Antioxidant with Alkyl Hydroperoxide Defense Properties in Yeast
1999
Copper-stimulated Endocytosis and Degradation of the Human Copper Transporter, hCtr1
2003
Altered microglial copper homeostasis in a mouse model of Alzheimer’s disease
2010
A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution
1999
Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development
2001
Copper transport into the secretory pathway is regulated by oxygen in macrophages
2009
Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase
2014