Standout Papers
- Immunosuppressive factor(s) specific for L-glutamic acid(50)-L- tyrosine(50) (GT). II. Presence of I-J determinants on the GT-suppressive factor (1977)
- Immunosuppressive Factor(s) Specific for L-Glutamic Acid50-L-Tyrosine50 (GT) (1977)
- Antigen-Specific T Cell-Mediated Suppression (1978)
- Antigen-specific T-cell-mediated suppression. I. Induction of L-glutamic acid(60)-L-alanine(30)-L-tyrosine(10) specific suppressor T cells in vitro requires both antigen-specific T-cell-suppressor factor and antigen (1978)
- Correlation between structural characteristics and immunological properties of the terpolymer L‐glutamic acid60‐L‐alanine30‐L‐tyrosine (1977)
- Immunosuppressive factor(s) specific for L‐glutamic acid50‐L‐tyrosine50 IV. In vitro activity and immunochemical properties (1977)
- Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor. (1977)
- Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). I. Production, characterization, and lack of H-2 restriction for activity in recipient strain. (1977)
- Idiotypic Analysis of Anti-GAT Antibodies (1978)
- Restriction of primary responses to the IgG class and dependency of IgM responses on secondary immunization for the copolymers of L-glutamic acid, L-tyrosine, and L-alanine. (1977)
- Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells. (1977)
- Idiotypic analysis of anti-GAT antibodies. I. Presence of common idiotypic specificities in both responder and nonresponder mice. (1978)
- Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions. (1983)
- Antigen-specific T cell-mediated suppression. II. In vitro induction by I-J-coded L-glutamic acid50-L-tyrosine50 (GT)-specific T cell suppressor factor (GT-T8F) of suppressor T cells (T82) bearing distinct I-J determinants. (1978)
Citation Impact
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Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. II. Demonstration of idiotypic determinants on suppressor T cells.
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Two distinct allotypic determinants on the antigen-specific suppressor and enhancing T cell factors that are encoded by genes linked to the immunoglobulin heavy chain locus.
1982
The human T-cell receptor α-chain gene maps to chromosome 14
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Mechanisms of regulation of cell-mediated immunity. II. Induction and suppression of delayed-type hypersensitivity to azobenzenearsonate-coupled syngeneic cells.
1978 StandoutNobel
Identification of antigen receptor-associated structures on murine T cells
1985 StandoutNatureNobel
In vivo effects of anti-Ia alloantisera. I. Elimination of specific suppression by in vivo administration of antisera specific for I-J controlled determinants.
1978 StandoutNobel
Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.
1983
The involvement of suppressor T cells in Ir gene regulation of secondary antibody responses of primed (responder X nonresponder)F1 mice to macrophage-bound L-glutamic acid60-L-alanine30-L-tyrosine.
1978 StandoutNobel
Suppressor-cell induction in vitro. IV. Target of antigen-specific suppressor factor and its genetic relationships.
1978
Idiotypic analysis of monoclonal antibodies to poly(Glu60Ala30Tyr10).
1979 StandoutNobel
Limited diversity of the rearranged T-cell γ gene
1985 StandoutNatureNobel
The I-J subregion codes for determinants on suppressor factor(s) which limit the contact sensitivity response to picryl chloride
1977 StandoutNobel
Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors.
1980 StandoutNobel
Developmental regulation of T-cell receptor gene expression
1985 StandoutNatureNobel
Helper and suppressor T cell factors
1980 StandoutNobel
Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents.
1994 StandoutNobel
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification
1983 StandoutNatureNobel
The Immune Response Genes of the Major Histocompatibility Complex
1978 StandoutNobel
Reconstitution of antigen-specific suppressor activity with translation products of mRNA
1982 StandoutNatureNobel
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. III. Interaction of effector suppressor T cells is restricted by H-2 and Igh-V genes.
1980 StandoutNobel
Functional and molecular organisation of an antigen-specific suppressor factor from a T-cell hybridoma
1980 Nature
IL-7 Induces Immunological Improvement in SIV-Infected Rhesus Macaques under Antiviral Therapy
2006 StandoutNobel
Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) II. Cellular source and effect on responder and nonresponder mice.
1977 StandoutNobel
Soluble factors in tolerance and contact sensitivity to 2,4-dinitrofluorobenzene in mice. III. Histocompatibility antigens associated with the hapten dinitrophenol serve as target molecules on 2,4-dinitrofluorobenzene-immune T cells for soluble suppressor factor.
1979
Fine specificity of antibodies to poly(Glu60Ala30Tyr10) produced by hybrid cell lines.
1979 StandoutNobel
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences
1984 StandoutNatureNobel
Reduction of syngeneic tumor growth by an anti-I-J-alloantiserum.
1977 StandoutNobel
Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.
1977 StandoutNobel
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes
1984 StandoutNatureNobel
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.
1995
Feedback suppression of the immune response in vitro. I. Activity of antigen-stimulated B cells.
1980 StandoutNobel
Unusual organization and diversity of T-cell receptor a-chain genes
1985 StandoutNatureNobel
Recurrent idiotopes and internal images.
1982 StandoutNobel
Selective suppression of the major idiotypic component of an antihapten response by soluble T cell-derived factors with idiotypic or anti-idiotypic receptors.
1980
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
1986 StandoutNatureNobel
Interleukin 2 Signaling Is Required for CD4+ Regulatory T Cell Function
2002
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+T cells
2001
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone
1984 StandoutNatureNobel
Constant region determinants on the antigen-binding chain of the suppressor T-cell factor
1982 Nature
Presence of interchain disulfide bonds between two gene products that compose the secreted form of an antigen-specific suppressor factor.
1981
Antigen-specific t lymphocyte clones. II. Purifcation and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells
1981
The Role of Antigen-Specific T Cell Factors in the Immune Response
1980
Monoclonal antibodies that recognize the product controlled by a gene in the I-J subregion of the mouse H-2 complex.
1981
Suppression of antibody and T cell proliferative responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor.
1980
Idiotypic analysis of antibodies to poly(Glu60Ala30Tyr10): interstrain and interspecies idiotypic crossreactions.
1978 StandoutNobel
Genetic control of a shared idiotype among antibodies directed to distinct specificities.
1980 StandoutNobel
Epitope-specific and idiotype-specific cellular interactions in a model protein antigen system
1980
Recalibrated linkage map of Escherichia coli K-12
1976
Mechanisms of regulation of cell-mediated immunity. III. The characterization of azobenzenearsonate-specific suppressor T-cell-derived-suppressor factors.
1979 StandoutNobel
Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes
1981 StandoutNatureNobel
The scanning model for translation: an update.
1989 Standout
Apoptosis in AIDS
1993 StandoutScienceNobel
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Shared idiotypic determinants on antibodies and T-cell-derived suppressor factor specific for the random terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10.
1979 StandoutNobel
Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. V. Role of idiotypes in the suppressor pathway.
1980 StandoutNobel
Antigen-specific suppressive factor produced by a transplantable I-J bearing T-cell hybridoma
1979 Nature
Glucocorticoid-Induced TNF Receptor Family Related Gene Activation Overcomes Tolerance/Ignorance to Melanoma Differentiation Antigens and Enhances Antitumor Immunity
2006 StandoutNobel
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
1990
Mechanisms of regulation of cell-mediated immunity. IV. Azobenzenearsonate-specific suppressor factor(s) bear cross-reactive idiotypic determinants the expression of which is linked to the heavy-chain allotype linkage group of genes.
1979 StandoutNobel
Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes.
1987 StandoutNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Antigen-specific T cell-mediated suppression. V. H-2-linked genetic control of distinct antigen-specific defects in the production and activity of L-glutamic acid50-L-tyrosine50 suppressor factor.
1980 StandoutNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Partial biochemical characterization of IgG1‐inducing factor
1985
Works of Jacques Thèze being referenced
Idiotypic analysis of anti-GAT antibodies. I. Presence of common idiotypic specificities in both responder and nonresponder mice.
1978 StandoutNobel
Human severe combined immunodeficiency disease: phenotypic and functional characteristics of peripheral B lymphocytes.
1990
Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor β chain (IL-2Rβ)
1995
Lack of intermediate‐affinity interleukin‐2 receptor in mice leads to dependence on interleukin‐2 receptor α, β and γ chain expression for T cell growth
1996
Hyper-IgM immunodeficiency syndrome: Influence of lymphokines onin vitro maturation of peripheral B cells
1992
HIV infection
2004
Interleukin 2 and its receptors: recent advances and new immunological functions
1996
Structure-function study of the p55 subunit of murine IL-2 receptor by epitope mapping
1991
Antigen-Specific T Cell-Mediated Suppression
1978 StandoutNobel
A polyclonal assay for T helper function involving T-B cell contact mediated by L3T4 molecules.
1986
The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.
1985
Differential effects of monoclonal antibodies anti-L3T4 and anti-LFA1 on the antigen-induced proliferation of T-helper-cell clones: Correlation between their susceptibility to inhibition and their affinity for antigen
1985
p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei.
1988
Isotype regulation of antibody production: T-cell hybrids can be selectively induced to produce IgG1 and IgG2 subclass-specific suppressive immunoglobulin-binding factors.
1983
The limited diversity of the mouse gamma-chains anti-GAT repertoire does not seem to be noticeably amplified upon class switch.
1982
Antigen-specific T-cell-mediated suppression. I. Induction of L-glutamic acid(60)-L-alanine(30)-L-tyrosine(10) specific suppressor T cells in vitro requires both antigen-specific T-cell-suppressor factor and antigen
1978 StandoutNobel
Immunosuppressive Factor(s) Specific for L-Glutamic Acid50-L-Tyrosine50 (GT)
1977 StandoutNobel
Analysis of antibody diversity: V-D-J mRNA nucleotide sequence of four anti-GAT monoclonal antibodies. A paucigene system using alternate D-J recombinations to generate functionally similar hypervariable regions.
1983 StandoutNobel
Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) III. Immunochemical properties of the GAT-specific suppressive factor.
1977 StandoutNobel
Regulation of interleukin 2 (IL2) receptor expression: IL 2 as an inducing signal for the expression of its own receptor on a murine T helper cell line
1985
Restriction of primary responses to the IgG class and dependency of IgM responses on secondary immunization for the copolymers of L-glutamic acid, L-tyrosine, and L-alanine.
1977 StandoutNobel
Immunosuppressive factor(s) specific for L‐glutamic acid50‐L‐tyrosine50 IV. In vitro activity and immunochemical properties
1977 StandoutNobel
Evidence for negative regulation of T cell growth by low affinity interleukin 2 receptors.
1987
IL-4 plays a dominant role in the differential development of Tho into Th1 and Th2 cells
1992
Functional analysis of GAT-specific T cell clones: H-2-restricted monoclonal T helper cells do not regulate expression of antibody isotypes.
1982
Idiotypic Analysis of Anti-GAT Antibodies
1978 StandoutNobel
Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). III. Generation of suppressor T cells by a suppressive extract derived from GT-primed lymphoid cells.
1977 StandoutNobel
Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2‐binding site
1987
Immunosuppressive factor(s) specific for L-glutamic acid(50)-L- tyrosine(50) (GT). II. Presence of I-J determinants on the GT-suppressive factor
1977 StandoutNobel
Further Analysis of Interleukin-2 Receptor Subunit Expression on the Different Human Peripheral Blood Mononuclear Cell Subsets
1998
Mapping of the Structural Genes of the Three Aspartokinases and of the Two Homoserine Dehydrogenases of Escherichia coli K-12
1974
Induction by i-j-coded l-glutamic acid50-l-tyrosine50 (gt)- -specific t cell suppressor factor (gt-tsf) of suppressor t cells (ts2) bearing distinct i-j determinants.
1978
Genetic control of the immune response to the terpolymer L‐glutamic acid60‐L‐aIanine30‐L‐tyrosme10 (GAT): II. Characterization of a cross‐reactive idiotype associated with anti‐GAT antibodies from responder and nonresponder mice
1979
Antigen-specific T cell-mediated suppression. II. In vitro induction by I-J-coded L-glutamic acid50-L-tyrosine50 (GT)-specific T cell suppressor factor (GT-T8F) of suppressor T cells (T82) bearing distinct I-J determinants.
1978 StandoutNobel
Threonine Locus of Escherichia coli K-12: Genetic Structure and Evidence for an Operon
1974
Genetic control of the immune response to the GAT terpolymer. I. Interstrain and interspecies cross-reactive idiotype.
1979
Immunosuppressive factor(s) specific for L-glutamic acid50-L-tyrosine50 (GT). I. Production, characterization, and lack of H-2 restriction for activity in recipient strain.
1977 StandoutNobel
Correlation between structural characteristics and immunological properties of the terpolymer L‐glutamic acid60‐L‐alanine30‐L‐tyrosine
1977 StandoutNobel
Probing VH gene-family utilization in human peripheral B cells by in situ hybridization
1991