Citation Impact
Citing Papers
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The roles of intrinsic disorder in protein interaction networks
2013
An omics perspective of protein disorder
2011
Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA)
2008
Breast cancer
2019 Standout
Patented small molecule inhibitors in the ubiquitin proteasome system
2007
Plasticity in PYD assembly revealed by cryo-EM structure of the PYD filament of AIM2
2015
Structural insight into the TFIIE–TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
2008
Head and neck squamous cell carcinoma
2020 Standout
Signaling pathways in retinoid chemoprevention and treatment of cancer
2004
The SKIV2L RNA exosome limits activation of the RIG-I-like receptors
2014
Protein Conformational Switches: From Nature to Design
2012
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Structural Disorder in Eukaryotes
2012
Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor
2012
Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation
2013
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Small-Molecule Inhibition of c-MYC:MAX Leucine Zipper Formation Is Revealed by Ion Mobility Mass Spectrometry
2012 StandoutNobel
Intrinsic disorder in scaffold proteins: Getting more from less
2008
Role of intrinsically disordered protein regions/domains in transcriptional regulation
2008
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Pfam: the protein families database
2013 Standout
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Activation and regulation of the inflammasomes
2013 Standout
The Structure of the yFACT Pob3-M Domain, Its Interaction with the DNA Replication Factor RPA, and a Potential Role in Nucleosome Deposition
2006
The Human Transcription Factors
2018 Standout
Translational genomics of nasopharyngeal cancer
2019
Unfoldomics of Human Genetic Diseases: Illustrative Examples of Ordered and Intrinsically Disordered Members of the Human Diseasome
2009
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
Structural disorder promotes assembly of protein complexes
2007
Functional classification of scaffold proteins and related molecules
2010
Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
2008
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Nucleotide Excision Repair in Human Cells
2013 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
BRCA1 and its toolbox for the maintenance of genome integrity
2009
Comparing Models of Evolution for Ordered and Disordered Proteins
2009
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
2011 StandoutNobel
Epstein-Barr virus-associated gastric adenocarcinoma
2019
Role of intrinsic disorder in transient interactions of hub proteins
2006
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Age-related macular degeneration
2018 Standout
How viruses hijack cell regulation
2010
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Intrinsic disorder in cell signaling and gene transcription
2011
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
Epstein–Barr virus: 40 years on
2004 Standout
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Targeting ubiquitin specific proteases for drug discovery
2007
DDK Phosphorylates Checkpoint Clamp Component Rad9 and Promotes Its Release from Damaged Chromatin
2010
The interplay between structure and function in intrinsically unstructured proteins
2005
Prediction of Protein Binding Regions in Disordered Proteins
2009
A dynamic model for replication protein A (RPA) function in DNA processing pathways
2006
ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome
2007 Standout
Inflammation and its role in age-related macular degeneration
2016
Progress of Structural Genomics Initiatives: An Analysis of Solved Target Structures
2005
Evaluation of disorder predictions in CASP9
2011
Flexible nets
2005
The annealing helicase HARP protects stalled replication forks
2009
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair
2009 StandoutNobel
Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair
2007
DNA Distress: Just Ring 9-1-1
2009 StandoutNobel
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
Intrinsic Disorder in Proteins Involved in the Innate Antiviral Immunity: Another Flexible Side of a Molecular Arms Race
2013
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Epstein-Barr Virus-Encoded Bcl-2 Homologue Functions as a Survival Factor in Wp-Restricted Burkitt Lymphoma Cell Line P3HR-1
2009
Growth of novel protein structural data
2007 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Tumour stem cells and drug resistance
2005 Standout
Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation
2010
An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
2012 StandoutNobel
Bovine Viral Diarrhea Virus Core Is an Intrinsically Disordered Protein That Binds RNA
2007 StandoutNobel
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2
2009
Viral Proteomics
2007
Deubiquitinating Enzymes as Novel Anticancer Targets
2007
Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins
2007
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53
2007
Structural divergence is more extensive than sequence divergence for a family of intrinsically disordered proteins
2013
Multivalent Binding of p53 to the STAGA Complex Mediates Coactivator Recruitment after UV Damage
2008
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Physical Interaction between Replication Protein A (RPA) and MRN: Involvement of RPA2 Phosphorylation and the N-Terminus of RPA1
2009
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy
2013
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
2008
Intrinsically Disordered Proteins in Human Diseases: Introducing the D2Concept
2008
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Replication protein A: directing traffic at the intersection of replication and repair
2010
Disorder Predictors Also Predict Backbone Dynamics for a Family of Disordered Proteins
2011
Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins
2007
Stem cell origin of cancer and differentiation therapy
2004
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
2016 StandoutNobel
Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms
2006
Quaternary structures of tumor suppressor p53 and a specific p53–DNA complex
2007
Works of Jack Liao being referenced
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A
2005
A novel member of the split βαβ fold: Solution structure of the hypothetical protein YML108W from Saccharomyces cerevisiae
2003
The Central Region of BRCA1 Binds Preferentially to Supercoiled DNA
2009
Structure of the p53 Binding Domain of HAUSP/USP7 Bound to Epstein-Barr Nuclear Antigen 1
2005
Preferential binding of IFI16 protein to cruciform structure and superhelical DNA
2012
Characterization of genes which exhibit reduced expression during the retinoic acid-induced differentiation of F9 teratocarcinoma cells: involvement of cyclin D3 in RA-mediated growth arrest
1998
Interferon-Inducible Protein 16: Insight into the Interaction with Tumor Suppressor p53
2011
Characterization of Segments from the Central Region of BRCA1: An Intrinsically Disordered Scaffold for Multiple Protein–Protein and Protein–DNA Interactions?
2004